The Deep Chemistry of Life and Death | Nick Lane | Talks at Google

[@kepa9787]

Wonderful speaker and so articulate to explain complex science

[@robbie_]

Very interesting guy. Just bought his new book on Audible. Look forward to listening to it.

[@issyjas3309]

Brilliant guest and interviewer, thoroughly recommend nicks other books as well

[@josephtaylor6285]

Currently reading Nick’ s book Power,sex and suicide, Mitochondria and the meaning of life. Well written and a great review as I go on to Bio 2 next semester 😅

[@ifeelikedyeing]

Nick Lane is a GOAT ✨️🔥🙏💯

[@zebulon5768]

I was looking for so much from this talk. Got very little about the scope of the new book and salient highlights. 😢

[@josephtaylor6285]

Interviewer isn’t quite up to the task. Nick graciously saves him.

[@YashoShasho]

Fascinating! ❤

[@snekhai]

Fascinating how a boring piece of undergraduate biochemistry can be an exciting topic to duscuss.

[@medeabeglarishvili6527]

Not related to this video, asking Google. Have you removed re:work English version of site or why I only see the Japanesse version? Please, answer 🙏 thanks!

[@glenliesegang233]

Information+highly complex information-specified constructed matter ( the Word and the Flesh) is at the center of life.

[@rossfriedman6570]

Could we make atp batteries?

[@uruksumer4101]

nice

[@icls9129]

Ugh, I didn't find the discussion interesting. Nick's books are much better, and just listening to him alone is much better. Let him organize the talk himself, rather than this interview style.

[@bobkoure]

Agreed. It would have been nice if the interviewer had more of a background in biochemestry or at least biology. Nick can do an amazing job if you just give him the floor, let him do his thing. That said, I come out of high tech - companies there tend to do talks internally with 'interesting' visitors for the benefit of their employees. As a side not that might have been the genesis of TED talks. At least this one made its way to YT.

[@lesliecunliffe4450]

"Deep chemistry"? Is that a case of being in it up to your neck? How does 'deep chemistry match up with science as limited by causal explanation?

[@Applepie409]

The biochemistry of bacteria is totally different to our cells. The bonds in carbon builds chains which is quite unique. Is silicon used in computing? Is xenon used in making computer chips? Respiration involves hydrogen and electrons but forget the details.

[@Applepie409]

Anaethetics and pain killers interesting topic.

[@bobkoure]

Nick's 'Transformer' does a decent job of showing that the boichemestry of bacteria and 'our cells' (eucaryotes) are very similar. Both depend on proticity to drive reactions. The major difference is that bacteria use their membranes to carry that charge difference so they're limited by the connection between volume and surface area - and eucaryotes have their charge difference on the membranes inside mitochondria (the 'christae') that unlinks that connection - and is probably what made multicellular life possible. Maybe read the book?

[@patrickperesuodei832]

Arguably even more important are the practical connotations for metabolism and our own health today. Is the Krebs cycle at the heart of metabolism because life was forced into existence that way, by thermodynamics - fate! - or was this chemistry invented later by genes, just a trivial outcome of information systems that could be rewired, if we are smart enough? Is the difference between ageing and disease an tractable outcome of metabolism, written into cells from the very origin of lite, or a question for gene editing and synthetic biology to come? That in turn boils down to genes first or metabolism first? The thrust of this book is that energy is primal - energy flow shapes genetic information. I will argue that the structure of metabolism was set in stone (perhaps literally in deep-sea rocky vents) from the beginning. Among the other things I learned from this book are the importance of Otto Warburg, why men get mitochondrial diseases more than women do (there is some speculative component here), why respiration is suppressed with age, why the brain prefers to burn glucose, what it might mean to think of cancer as "growth-based" rather than genes-based, and most of all the importance of the Krebs cycle and reverse Krebs cycle for a broader array of biological questions. The final section considers why chloroform seems to rob fruit flies of their "consciousness." I can't pretend to evaluate the more controversial claims of the author, but at the very least I learned a great deal reading this book and it has stimulated my interest in the topic areas more generally.

[@patricklall4433]

Poorly moderated. People who work at Google have no business engaging in public discussion (especially when they haven't a clue about the subject matter). They should stick to what they're good at - making money and a brand of themselves.

[@MaryJones-d7e]

Davis Gary Clark Barbara Moore Gary

[@SpenderDebby-x6n]

Harris Eric Hernandez Dorothy Davis Jennifer

[@glenliesegang233]

Life is the information driven transformation of energetic molecules (or atoms as in proton gradient driven hydrothermal vents or direct energy absorption by chlorophyll,) to simpler ones and the use of thst energy to take simpler molecules into highly highly specific new utterly complex systems of molecules which direct the transformation of other molecules. Where does highly complex digital base 4 unidirectionally read, uni-stranded information come from? Only a Superintelligence is capable of imagining and building the first 2 genomes, and, simultaneously, all the necessary machinery, all in a lipid bilayer.

[@remusracingro3884]

First

[@peters972]

It would be ironic and likely that the secret of life’s emergence is hidden in the most boring biology lesson, instead of the excitement of praise and worship of God. However, I did not find the Krebs cycle that boring, it was the classification stuff I found intolerable. And, we can thank the Lord for the Krebs cycle. The Lord is in the details, not the bloody devil.

[@عليالعراقي-ع2ت3ي]

علي موحان🎑💛🎑💛👏💛👏💛🎑💛💛🎑💗🎑💛🎑💛🎑💗💗🎑💛🎑💗🎑💗🎑💛🎑💛🎑💓💓🎑👍🎑👍🎑💗🎑💗🎑💛💛🎑💛🎑💛🎑🎁🎑🎁🎁🎑🎁🎑🎁🎑🎁🎑🎑🎑

[@Applepie409]

Difficult to keep comments respectful with this post

[@Applepie409]

Meant for user not the video. The video is core. In seeking the truth we can end down a rabbit hole. Many a professional spends his or her life specializing in a field which is a blind alley. The hydrogen pump, ATP. Must read about the Cambrian explosion.

[@Applepie409]

The beginning of life fascinating. This is what gets people hooked along with the noble peace prize in biochemistry and molecular biology.

[@Applepie409]

Rewiring of metabolism, why do we have exons? So many questions….. Don’t we have switches in the cell growth cycle and this is different in cancer.

[@Applepie409]

Why does arthritis feel more pronounced in cold weather? Why is pain relieved by a hot compress? I love the humble comment that he hates preaching to people.

[@designstudio8013]

There is a force called the rolling force that powers everything and keeps everything in motion. This force eventually breaks thru your luminous body causing physical death. You then transfer into another frequency.

[@genesmith3582]

no

[@ianj5989]

Nonsense

[@peterb2272]

😂

[@0tt0z]

😅😅😅😅

[@peterb2272]

Can you show me the experimental data proving this please.