The heart makers

[@Mikej1592]

it's research like this that makes me sleep better at night as I get older

[@jeremiahfisher6994]

I know right

[@Tony_Re-imagined]

how does this make you sleep better...

[@Mikej1592]

@@FruitBanana420 creating hearts when I have a family history of males dieing from massive heart attacks so yeah, this helps me sleep better at night knowing there are people out there doing a science

[@kalyanimanickavasakam3883]

@@Mikej1592 Still alive after 7 years lol

[@2.siskyz491]

Like u dont got to worry no more..u can get a made heart if something happens

[@piper3981]

I would just like to thank you for making this video. I am currently having to do a biology report on the research question "will the decellularization of human heart tissue exempt the need for human heart transplants in 50 years?" and this video got me out of a lot of strife. Thank you from the bottom of my heart (pun intended).

[@GeeKayKayGee]

This, this is the type of show, information, video, material that should be shown on channels such 'History' and 'Discovery' and 'The Learning Channel' . Thank you thank you thank you. It's educational, it's entertaining, it's enlightening and there wasn't one single toddler in a tiara to be seen. Thank you thank you thank you.

[@shawnmatthews5118]

I had become utterly depressed about recovering from my heart failure and I know time is running out for me. I pray they will get this ready for human trials before it’s too late for me.

[@brutallyhonestguy5985]

If I'm not being rude , how old are you

[@shawnmatthews5118]

54

[@Apricotut]

Hey are you doing well?

[@shawnmatthews5118]

@@Apricotut no.

[@Apricotut]

@@shawnmatthews5118 I’m sorry

[@min-gv6zb]

How did I go from looking at kazoo videos to this.

[@young_kikuijn1997]

Lmaooo don't worry man. I came from how to take care of turtles to this 😂😂

[@dabunnyrabbit2620]

😂😂😂

[@justkev1044]

Everything is Lego now

[@cristi37]

I came from cannibalism to this video

[@paullol7852]

i watched minecraft vids to this

[@shamdande9094]

We salute the heart makers &wish every success in making wish to create new milestone

[@Mistfall254]

This breakthrough will easily the issue of organ transplant patients that need a heart!

[@crippled.6749]

But it'll probably be very expensive

[@Mistfall254]

+Victor Flores Yes, but the benefits out way the risks

[@andrewke694]

Anyone else enjoys learning but still feel squwimish? I've been trying to fight this feeling for years because I love hearing about amazing researches like these videos c:

[@Liberty309]

7 years later and not a word !

[@moonbugz]

We learned about this in My honors Biology class! The fact that they’re able to do this using the extra cellular matrix and stem cells (and the fact that each individual cell knows what to do, even when not connected with the brain through neurons) is really cool! It’s really awesome to think about weird, fascinating things like this

[@wardahshoaib6270]

will this heart survive for a long time because its tissues musy be already weak

[@fightfannerd2078]

it should

[@AbdulQadeer-kf3vo]

Government should invest in this instead of military...

[@mrgameandsnacks1379]

I agree, unfortunately until war and the threat of war over the military is necessary

[@michaeljordan9952]

Abdul Qadeer really

[@fangadorawolfen6164]

We spend because most of our allies spend so little.

[@Max7770_0]

Ask to your country first.

[@c.jishnu378]

They sure have a big heart!

[@pjdelekto78]

Wow I do actually want to know how they did this even when they took the cells out its actually pretty interesting.

[@Lordy-Lord]

Science

[@RukudzoKadiramwando]

😂​@@Lordy-Lord

[@calliope4293]

The creation of lab-grown hearts and the search for a cancer cure both involve advanced research but differ in complexity and goals. Both require cutting-edge technology and face challenges in replicating complex biological systems. Lab-grown hearts focus on engineering fully functional organs for transplants, which is a clear, structured goal. In contrast, cancer research must tackle a wide range of diseases, each with unique genetic mutations and behaviors, making a universal cure difficult. While progress has been made in both areas, lab-grown organs are not yet ready for widespread use, and cancer treatments, though more effective in some cases, still lack a one-size-fits-all cure.

[@chokeonthis2932]

So they didnt make a new heart, they re-equipped an old one with cells, is what im getting from it. definitely still amazing, I was hoping it was grown from scratch though, for research reasons, never mind i shall still use it.

[@fireteamomega2343]

That would be cool if they combined imaging tech and created a 3d protein printer to create the scaffolding.

[@jokerbookshop]

Great extra cellular matrix work.

[@Gvtteddybear]

Does the decellularization process destroy brain cells and their synapses?

[@israelcenteno4820]

Best suited for restructuring damaged heart caused by heart attack.

[@dotdotdot1113]

how about all the nerves that need to connect to the ventricular muscles? The heart needs to contract twice to achieve double circulation and relay neurones need to be attached to the heart in order to achieve unconscious muscle contraction

[@scrapwoodloft8123]

ummm how do they do make the heart beat regular after current heart transplants... pacemaker!

[@blueprime6429]

Is it just me or did my heart beat in rythm to the beginning

[@fantamize]

Incredible! Woo, how technology and ideas have come.

[@JohnSnow-gd9dj]

any update? 10 years later

[@mustachesally4134]

I'm sure the rich and corporations can't wait to get their hands on these when it becomes available. It will take several hundreds of years to develop these out of a lab on a mass scale because while they can make these hearts, scientist have not entirely figured out how the human heart cardiac cells work and why they are the way they are made. They have not uncovered the full design of the heart.

[@1nvd]

@labobo there's still plenty of research and trial and error for them to fully grow human hearts from scratch. Same thing applies to 3D printing organic parts

[@MrAzam1991]

this is quite impressive and motivative video.

[@r.a.8861]

in the next 10-20 yrs this will all be outdated. This will get much faster and more exploited

[@osborl12]

I wonder how they keep the protein frame from rotting.

[@gabey.5216]

Man I wonder what kind of jobs these people have. Very interesting.

[@thecauldron2212]

Same, love to have one of those.

[@witch3lle759]

Biomedic engineer

[@CHB94]

I miss a flap in my heart, and people often ask me how i feel is it's hard and then i need to tell them that it's not bad, that i feel great. but when i told my gym teacher this SHE started to panic and saying "Did i push you to hard? Are you ok" so after the class i had to speak with her. My classmates knew this and some stayed with me to see if the teacher did not feel like shit. the heart is one amazing organ.

[@GeeKayKayGee]

I sympathize with your sentiment but as television, for many, is their prime source of information and entertainment. As such I think it is very important to press for the lowest signal to noise ratio possible. Less dreck and more substance is surely a desirable thing.

[@takoda598]

Do they make a new heart from scratch or reused a cadaveric heart to work again?.

[@melindachambers5397]

my daughter was born with hypo plastic left heart if this is possible this can save many many babies born with heart defects!! its amazing!!! my daughter has health issues now. but maybe this could prevent ongoing health issues!!

[@AngrySinn]

All this is incredibly fascinating to me and I need more... I still can't decide on whether I should study to become a marine biologist or study in the biomedical field 🤔

[@danijel124]

AngryFish 5 biomedical definetly :)

[@filipe_paixao]

@A dumb Idiot well... in the past I thought about that to, but for research you need money or people to invest in you. So I let go of that and chose software and hardware engineering. I was thinking on combining the 2 by using bio-ships, amd seeing this kind of research developed brings me joys since I have more possibilities to work on

[@dmeditz8100]

Marine science have sexy life good excercise fresh air meeting attractive ladies in cool every new type of bikinis and most important beauty of Ocean and corals.

[@FlamerzZz]

Anyone spotted the WD40 ? lol

[@762459]

+FlamerzZz you're gonna' need some lube at some point

[@doggonemess1]

+FlamerzZz WD-40 keeps thing moving, duck tape keeps things stuck. You don't need anything else! Ironically, they were both invented to keep water off of things. I never thought of that correlation before.

[@hobnobs6445]

+doggonemess WD in WD40 is Water Displacement

[@dormantrabbits]

That shit will fix anything!

[@urbanwarchief]

Science is important but we must never forget to question it constantly

[@manojprajapati1761]

It's 2021, I wonder how much they have progressed

[@osaka69420]

Yeah.

[@mikeavery4098]

Can't you just scan a heart and replicate the scaffolding with a 3D printer using biodegradable material that degrades after 5 or 6 weeks and use stem cells along with heart cells to grow a heart in the biodegradable scaffolding it seems like you guys are doing it the hard way when all you need is a little bit of crisper and a little bit of stem cells from a placenta.

[@lordmcswain1436]

Could they have a scaffold made of flexible cellulose?

[@anti-matter5874]

My issue with with it is that after this is successful will we be able to copy fresh hearts on demand?

[@2Moonn]

Anti- Matter 10/10 grammar

[@rishivathul4677]

what if the replacement part is rejected and it causes heat failure

[@Wriggs74]

R.I.P to the human who has donated their heart, so that millions or billions may now survive.

[@nightrous3026]

how do they make the hearts nervous system though?

[@theblackfox6536]

This could help a lot of people, including me with my bad heart.

[@istvanszekely4842]

And What happen if they use the right or the left lung like a blood pump. After some artifical modification it can transport blood instead of the heart, without external powersourch.

[@riazalean7158]

They decellurized it to make the heart to accept the donar parts to the recipient but the fact is how recipient heart is going to function when it accept it

[@kietpham8785]

what's the chemicals they use to wash out all the blood cells ?

[@isseismail4706]

Why is it yellow

Bravo!!! Well done! Perfect.....

[@saqib..]

This was 7 years ago, Imagine the progress they've made till now.

[@MSG689]

True

[@animeworlds.g4035]

why is it yellow

[@pelicanman96]

fat is yellow. there's a lot of fat around the heart

[@vinifryderyk4306]

Yellow = 0% blood 100% fat and arm

[@mrbomplastik]

It's usually red because of muscle cells that contain myoglobine (That's essentially what steals the oxygen from the haemoglobine) which is red (just like the hb). Now with the Muscle cells gone there's no more myoglobine and therefor no more color. What's left is the white extracellular matrix like collagene (tendons are also made from collagene)

[@pratyush287]

bcoz it has been stored in formalin so that tissue remain intact

[@SuperSimplekitchen]

Interesting...eventually the breakthroughs will come...

[@Loksfox]

No, are you assuming we only die from heart conditions?

[@thekeeeonproject]

If they do this with pig hearts then we have so many hearts to use, plz like my comment so more people can se

[@puroboludeo1]

So... it's a heart, or parts of it, made out of non-cellular tissue...?

[@shahanaalangadan7044]

A whole laboratory to make heart . And we were created in our mama's tummy. Btw that beats 5:32 is really cool❤️

[@kentlawton6446]

They should have tried for the Rh negative heart

[@alfredgonzalez6068]

can you used a bioprinter

[@programagor]

Why don't they 3D-print the structure from cartilage cells or something like that?

[@taxivulpesia]

chondrocytes are much more costly, though they are involved with the extracellular matrices. that is a fairly good question, and there is cartilage surrounding and supporting some interior regions of the heart. related to this, however, is a condition known as aortic acidogenic chondroma (AAC), which is caused by a variety of reasons, though the definitive starting point for these growths is (more often than not) the conus arteriosus and/or the valva. this chondroma may be the result of deformations during the 'rebuilding' of the chondric tissues/membranes, and these deformations have roots in environmental hazards, such as a heavy imbalance of acidophilic bodies escaping from the anterior pituitary gland (APG) and entering the bloodstream. for more information on the structures, without mention of the diseases that they may suffer from; \ vesalius.northwestern.edu/sections/FA.1.20.03.html

[@WHALEx3]

Why don’t they just print their own matrix?

[@Lastindependentthinker]

I have heard that you can use a substance from the confection industry to make the scaffold. Glucose I think?? apparently it dissolves after a while..

[@gotem6891]

the scaffold is primarily protein i think, glucose is a sugar

[@yeshuaaprylleboholst8975]

hey ummm why is the heart yellow anyway?

[@user-vj4wx3qp5b]

Why not every other organ as well. . .

[@jhutchyboy1]

Wait, so if they have made a heart, people could just keep getting these hearts and live forever?

[@potatoman1434]

That’s not how it works dude

[@jhutchyboy1]

@@potatoman1434 Bro I was like 13, I don't even remember watching this video, how tf did you find this comment

[@potatoman1434]

jhutchyboy ronni dude

[@kwasiwilliams5014]

So the question is how fast can this be done? Can they do this to an old mans heart while he is still living and put it back it cleaned and refurbished?

[@chibiprussia5574]

Kwasi Williams It's quicker than waiting. And, you have to take medications so that your body won't reject your new heart. This takes weeks, you being on the waiting list can take years.

[@MrSaint3]

Chibi Prussia the body will not reflect its own heart. The heart structure will be seeded with stem cells from the host body. The cells will be heat muscle cells and the like, amassing into tissue and them the entire unified organ. It will be all exactly the human host's cells so the body will not have an immune response. Well, that's only as much as I know.

[@chibiprussia5574]

Morning Saint I may have forgotten to say this, but getting a heart from someone else, will cause your body to reject it. Medication can solve this, but it's super expensive.

[@christopherholmes3510]

Question... what took so long to start on this?

[@slowjampopi3782]

Money

[@slowjampopi3782]

Don't click that link 👆

[@MrCanchay]

why? :)

[@Brett-kg7je]

+Dj Rockney Why? Please. My curiosity is killing me.

[@MrCanchay]

the guy has nothing else to do, simple as that. But don't click it anymore, its obsolete now.

[@RodrigoTeixeirasCosmos]

self repair

[@masaabsalh3114]

The future of transplantation recognizes the body for an organ so that it is not oxidized

[@omagawd6762]

At first i tought it was an albino heart

[@dabunnyrabbit2620]

face........ palm........

[@francissantiago3492]

I want to see scientists will make living human clone ^^

[@chandansharma3462]

Concious can't be created anywhere in the world.

[@gotem6891]

@@chandansharma3462 i mean you could try with artificial intelligence?

[@murnimira3480]

@@gotem6891 u could make intelligence but not feelings that start the conciousness

[@gotem6891]

@@murnimira3480 true true

[@legend2533]

I'm dancing with the beat

[@jacksoncooper3200]

Actually a good idea and could work

[@LordZygon]

Now we just need 3D printers capable of printing the proteins necessary for this and accurate enough to print them and we would no longer have to use transplants.

[@GodsCommunity]

Peaceful blessings. 💭

[@DirtyLifeLove]

Thought they made that heart. After 7 years and no donor less heart transplants. Yet, huge progress in AI, and Google storage schemes

[@erikdagdagan8314]

who are heve because they have health anxiety or hyphochondriacsis??

[@zee30000]

Looks like thinks are getting better but its not fast enough. It sucks I wish we had technology from the movies. self-replicating Nanobots that builds buildings, and other stuff in hoverboards an anti gravity chambers and huge Interstellar ships.

[@DelectableDays]

I'm willing to give them 30-40 years to create totally artificial organs and cure cancer/Alzheimer's. Make it snappy!

[@geraldoderibeirao2347]

zee30000 um... do you have any basic notion of physics? anti gravity skateboards whithout giagantic and super noisy fans are impossible

[@zee30000]

Lemon Ice Cream I wasn't really serious. it is the internet.

[@Lyle-xc9pg]

Then go out and do something. Whiny twat

[@dfghj241]

im doing biological sciences at university right now and im afraid that i'll never get to work in places like this because im not doing medicine... fuck medicine...

[@MrCanchay]

Paulo H Hey! I'm pursuing the challenge to grow human hearts in the most affordable way! I encourage you to visit this website www.beoteam.com/

[@dfghj241]

wow, thanks for sharing!

[@MrCanchay]

I encourage you to join ! :)

[@dfghj241]

A) i don't care for medicine B) if i did care i would need to pass through an exam in my country that i have absolutely no chance in a million years of passing, and so do not the other millions of people that do the test(competition is brutal).

[@juhapark7238]

this is so amazing!

[@vilmakatherinbecerralagos4084]

Amo la ciencia medica gracjas a ella se ha descubierto imortantes avances en detectar y curar enfermedades.

[@anyaforger2021]

Yo the title should be how to make a human heart from scratch 😂

[@rocksofoffence.righteousam2422]

They don't have that kind of Tech., yet.

[@justinejames5444]

Lol recommend 7 years post

[@lordice5]

I don't know how stupid this question is, but wouldn't a spinach heart rot?

[@ronemiralles9539]

no one youtube in 4050: How to make "heart" Diy

[@namnam7234]

why is the heart yellow?

[@exetramqqgameandmore9786]

menami lagran beacuse blood will make Red.

[@k.ganesanganesan6825]

Tireless work. You are nearing success. Ask people to maintain heart and lungs.

[@epiclife777]

This only last for hours after transplanting in animals. Maybe artificial heart can be better

[@RS_Redbaron]

This is all?

[@harvey4455]

It's bad when an informative video like this calls a heart an organ mate it's a muscle

[@chokeonthis2932]

Apparently its a muscular organ because it has its own function, google it. Whereas certain aspects of us are one or the other, such as skin (organ), bicep (muscle)

[@harvey4455]

@@chokeonthis2932 thank you for the tip pal

[@godsarmy111]

Can I be your first patient Robert in Az im in the hospital for my ❤️

[@JukaDominator]

Screw Tv, let all the garbage be concentrated there while we enjoy the GOOD things on the internet. At some point everyone will be able to have access to it so in time the masses can use it to its fullest potential and create better generations for all.

[@PierreRipplinger]

Only if they do the same with every other body parts, mostly brain tissues.

[@Yzkl_Lenhart]

frankenstein coming soon

[@BeanOnTheFlipside]

The brain is here

[@resthav0894]

*Who got this Reccomended after 7 Years*

[@l2dskins181]

Me lol...

[@suhassreehari876]

Me

[@hohoangel11]

What thayt yellow thing

[@ForboutinGames]

imagina fazer todos órgãos, um corpo inteiro, juntando os braços e pernas mecânicos, liga-lo ao cerebro. Pronto, chegamos a imortalidade! :3 imagine doing all organs, a full-length , joining the mechanical arms and legs , connect it to the brain . Ready, we come to immortality ! :3

[@jeremyviromek]

please hurry

[@francissantiago3492]

Do you have, problem on your heart ??????

[@Shindo13371]

Even if every part of the body could be grown and reintroduced/replaced as needed, there's still no understood way to clone or emulate the brain so that would be the inevitable point of failure.

[@esphy7515]

Why am I here?