The importance of TP53 in CLL

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VJHemOnc – Video Journal of Hematology & HemOnc

VJHemOnc – Video Journal of Hematology & HemOnc

2 жыл бұрын

In this video, Richard Rosenquist, MD, PhD, Karolinska Institute, Stockholm, Sweden, comments on the important role of TP53 in chronic lymphocytic leukemia (CLL), emphasizing its function as a tumor suppressor gene. Dr Rosenquist also explains how TP53 aberrations play a role in patient response to therapy and the growing importance of BTK inhibitors and BCL2 inhibitors as a treatment option for these patients. This interview took place at the 2022 European Research Initiative on CLL (ERIC) Meeting.
Explore our dedicated feature on genomic testing in CLL here: bit.ly/403y417
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