The Thyroid Gland and the Thyroid Hormone (T3 & T4)

The Thyroid Gland and the Thyroid Hormone (T3 & T4)…Thyroxine…Triiodothyronine, Tetraiodothyronine, Thyroglobulin. Thyroid stimulating hormone, iodide, iodine. Biology lectures for NEET, NEETPG, MCAT, DAT, PLAB, USMLE, NCLEX, COMLEX.
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[@lalunaasmr3508]

This has been the BEST video explaining the thyroid. I was diagnosed woth hypothyroidism in January and not even my doctor has made this whole process make sense to me! The humor also helps from making this boring and makes it so things stick to my brain. Youre awesome! SUBSCRIBED!

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Amazing vid as always. To the viewers: Don't forget to look into Hashimoto, it's a common quiz question opposed to Graves disease. ( I know it's in the vid but wanted to point it out) Thanks medicosis

[@MedicosisPerfectionalis]

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[@MedicosisPerfectionalis]

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Best video on the thyroid process!

[@MedicosisPerfectionalis]

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[@abdullahmohsin9028]

Great video as always. Just wanted to point out that at 12:43 & 13:07 you associated Goiter with Hyperthyroidism only. However, it is also a presentation in Hypothyroidism (Hashimoto's Thyroiditis, Lithium intake, Iodine deficiency etc.)

[@MedicosisPerfectionalis]

You’re correct! Goiter doesn’t have to be hyperthyroidism.

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[@MedicosisPerfectionalis]

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[@MedicosisPerfectionalis]

Thank you so much!

[@noor_8673]

Isnt thyroid hormone protein anabolic?? I am confused my book says it increases protein synthesis?

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[@hiteshbhati1242]

Hey Medicosis why there is diarrhoea in hyperthyroidism because if it stimulates sympathetic then sphincter tone would be very high so it should induce constipation rather than diarrhoea?? @medicosisPerfectionalis

[@MedicosisPerfectionalis]

It’s because hyperthyroidism stimulates gastrointestinal motility.

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can u please post video about hypo and hyper throidism in detail

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Always the best

[@MedicosisPerfectionalis]

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So am from just watching another video on Thyroid hormones nd i was soo not getting it Till I saw this Thank you mahnn You soo funny nd relatable 😅 God bless you

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God bless you too! Would you please help me by sharing?

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[@MedicosisPerfectionalis]

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[@mariapazsarmiento3826]

Hi @Medicosis Perfectionalis, I don't understand why when there's TBG deficiency it presents with low total T4, normal free T4 and normal TSH. Can you explain me please

[@MedicosisPerfectionalis]

Total T4 includes the free T4 (floating in the plasma) and bound T4 (bound to the taxi 🚕, known as TBG). If the number of Taxis (TBG) decrease, the number of taxi passengers (bound T4) will decrease, and therefore the total T4 is reduced. However, a reduction in the number of taxis will have no effect on the persons that walk to their work (free T4), and since the feedback loop (TSH) is based on the response to free T4 (which is normal), the TSH will be normal, because the free T4 is normal! Hope this helps!

[@mariapazsarmiento3826]

@@MedicosisPerfectionalis thank you so much 🤗🤗🤗🤗🤗 you are the best

[@sabnamjahan9341]

My T4 is 12.4 And TSH is 3.5 Is it normal?

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Magnifique ✨

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thanku

[@user-wy7gc7we7p]

Thank you so much you're really amazing but I still didn't understand what's the relationship between thyroid stimulating hormone and hypothyroidism and hyperthyroidism Why thyroid stimulating hormone increases in hypothyroidism and why thyroid stimulating hormones decreases in hyperthyroidism shouldn't it be the opposite?

[@user-wy7gc7we7p]

I think it has something to do with a negative feedback right? anyone can confirm that?

[@2ueuphoria]

usually for hyperthyroidism, you have a lot of t3 and t4 bc you have this anti-body acting like TSH like in graves disease, if it acts like TSH, it means it will give you a lot of t3 and y4 which causes negative feedback on pituitary so low you'll have low TSH in reality. hypothyroidism can be caused iodine deficiency so you can't form t3 and t4 so your body keeps releasing TSH hence you have low t3 and t4 but high TSH in hypothyroidism or it can be caused by some antibody now destroying your thyroid gland so not enough t3 and t4 so again high amount of TSH

[@user-pz3gl4rx6s]

Always good

[@MedicosisPerfectionalis]

Thank you 🙏

[@shehreeze1022]

So I’m a little confused, my Kaplan MCAT text book agrees that T3 and T4 are tyrosine with 3 and 4 iodines attached, BUT they disagree that they are lipid soluble. In fact, the book says that they are water soluble. Who do I listen to?!?

[@shehreeze1022]

So upon further research it seems that T3 and T4 are both classified as peptide hormones but they behave like steroid hormones because they are lipophilic, so they actually do cross the lipid bilayer of cells and bind to an intracellular receptor.