Thrombocytopaenia (low platelets) Overview - platelet physiology, classification, pathophysiology

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"Thrombocytopenia which means low platelets is associated with a variety of
conditions. Thrombocytopenia is defined as a platelet count below the lower limit of
normal (less than 150,000/microL). Platelets are produced in the bone marrow from
megakaryocytes. Each megakoryocyte produces 1000-5000 platelets.
Platelets play a key role in hemostasis forming a temporary plug. Therefore if you
have low platelets you are unable to for a temporary plug and tend to bleed more
easily. In order to understand platelet function, we need to revise hemostasis.
Hemostasis involves three main phases vasoconstriction, platelets plug formation
and coagulation"
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[@georgeelgin3903]

This is great background for the systematic biology of cytology !! One can't get the Why before one understands the How

[@JonDoesFlow]

I have just been diagnosed with ITP and this has helped me understand. You’re illustrations are excellent. Thank you.

[@tatiannabroadhurst2538]

what is it? I think my dad has it

[@user-xf9fr5wr7u]

Meet smart Lee she will help you recover ITP losses

[@user-xf9fr5wr7u]

She's on telegrams

[@user-xf9fr5wr7u]

smartlee111 The username

[@karolaynearaujo9955]

Thanks!!! You are helping a student from Brazil :)

[@ambreenghani6780]

Sir please also make a video on ITP vs TTP vs DIC vs HUS.. Show their characteristics and difference between them... And also Diagnostic tests performed for each of them

[@chemthroughbio]

You are so talanted! Your explanations are real useful!

[@Kristin2885]

@@adelinenmemo It's common to have this happen because rescue treatments like IVIG and platelet transfusions only work temporarily to get the platelet count out of the danger zone. Also the steroids they usually give you at the hospital initially are quickly tapered after you go home. Most of the time the platelets will start to crash back down again within a week or two. This then requires longer term treatment with steroids and slow taper (if you're responsive to them) and/or adding other treatments like Rituxan or Promacta (if you have great insurance). Hope you're recovered or stable by now. I am an ITP patient as well (twice had platelets less than 3 over 15 yrs, but perfect remission in between with platelets over 300, and back in remission now - achieved with 3-4 months of prednisone with slow taper after hospital rescue treatments both times). Good luck!

[@dammionpeaks2209]

Beautiful illustrations. Thanks

[@souvikkar4175]

SIR I HAVE NOTHING BUT RESPECT FOR U FOR ALL THE HARD WORK U DO JUST TO MAKE US BACKBENCHERS UNDERSTAND TRICKY TOPICS LIKE THIS BUT I WANTED TO THANK YOU FOR ANOTHER REASON CUS I CAME FIRST IN MY MED SCHOOL WITH FULL SCHOLARSHIP U MADE A FUCKING IDIOT A GENIUS THKU AND MAY GOD BLESS U WITH ALL THE SUCCESS U GET

[@kyeong-raekim6485]

Very nice video it helped me a lot to understand thrombocytopenic purpura and moreover the base of thrombotic disease!!!

[@DrAdnan]

More hematology please, I’m going through the sketchy vids rn so it complements it well 👏

[@User-to7nb]

I see you in every video

[@fatimaalarabi5581]

You're a lifesaver Armando Thank you so much 💗💗💗

[@PeydaPete]

Thank you, my man! Great explanation with great visuals! I have chronic ITP with about 10,000/mm³ (and weirdly no symptoms). This video helped me a lot to understand what's going on in my body :)

[@yollyobsequio8379]

Hi how are you now? I think i have this

[@PeydaPete]

@@yollyobsequio8379 Overall, I am fine. Though it's a bit complicated in my case. My numbers are really low but I have no symptoms at all. I'm fine in my everyday life, however in some cases (e.g. surgery) I need to get an infusion beforehand and I might need to take some drugs in case of an accident or something. It's more of an annoyance than anything, but then again it depends on what you do for a living or your hobbies. If you think, you have ITP yourself, you should definitely talk to a doctor about it. Depending on your actual values, treatment can vary a lot and it might also only be acute and not chronic.

[@ashelvherukayi]

You're indeed a life saver,

[@__anderson__7408]

So gonna be important for my Internal Medicine .Thanks

[@varshini_hegde]

Very helpful... Ty so much.. Your video has helped me a lot in my presentation

[@sanisch3223]

Thank you so much!!

[@Jaspreet-um1iv]

GANDHAK RASAYAN It helps to maintain the skin and blood vascular system healthy.thank you planet ayuveda

[@billzeitzmann1585]

Very clear and the Decisive video thank you very much

[@milicanedeljkovic7148]

This channel is amazing, keep up the good work❤

[@doc003]

EXCELLENT - lots of valuable information

[@nagatsatti8426]

Excellent and very nice thank you so much doctor

[@kcpoodlesofpa]

I appreciate your mentioning that ITP is not just platelet destruction but also reduced production. I think the theory is that the megakaryocytes are destroyed before they can even become platelets. I’m also told its now known as Immune TP not idiopathic.

[@nagulandevendran9728]

Thank you so much sir you are awesome, we able to understand clearly and easily 💙💙💙🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻thanks a lot

[@_chillPixel_]

Beautiful explanation.thankyou👏🏻👌🏼

[@ndhart3213]

ANONE ANONE! Am I the only person that commented about cells at work. WE NEED MORE PLATELET LOLIS!

[@shiikae7787]

George Piggy Platelet ftw

[@iMRREdy]

Excellent. Thank you

[@muzvarishonga]

Thank you so very much for making this topic clear and easy to understand... Is there a way to access your diagrams and notes? Thanks again.

[@shaheensharif3917]

Hi, I was thinking if you could mention in a bit detail about an important reason causing low platelets which is dengue fever, and related infections. Thanks

[@jithinmohan6336]

stunning diagrammatic representation ✨⭐.use more colours & make it more attractive 🎨. Nice Videos 😊

[@zishanrahman7208]

Great video! Thanks!

[@srirambhardwaj2343]

Very.very.thanks.forthis.lecture.

[@ahsanshah5339]

Very good

[@jadesmallman554]

Hey, love the videos. Would you be able to do some videos focussing on inotropes and vasopressers?

[@Systemrat2008]

Great video but it seems to fail to mention elevated platelet counts can result from rare MPN's such as polycythaemia vera or essential thrombocythemia and early stage myelofibrosis. High platelets can also be a result of an auto immune disorder. Anyway thanks for your video it was very informative. Just found one of your other video "Haematopoesis and Myeloproliferative Disorder - Overview" great work.

[@ambreenghani6780]

You are great Sir

[@user-uk6yw5bb2r]

u r my hero

[@unknownperson-pt7bf]

more thanks to you

[@sciencedelight]

Very interesting thankx

[@MadMed12]

best as usual

[@ProTroll69]

Anyone know WHY the antibodies might be destroying platelets? I have ITP and my bone marrow came back normal… My guess at this point is that the antibodies are running wild and need to be re-directed somehow.

[@NatA-ht3ug]

Thank you.

[@muamnfattah6353]

Thank you

[@Chopsyochops]

Thank you for this. Do you know if there is slink between iron Aneamia and low platelets? I have both.

[@drealove9351]

Hi Christina did u get red spots on skin I been suffering from this I got my iron up but I had work done on my mouth I think why my platelets is low did it increase

[@Chopsyochops]

@@drealove9351 my platelets are still low. Nothing changed. My iron drops every month so I’m unable to get iron levels high enough to see if it’s low iron that’s the cause.

[@drealove9351]

@@Chopsyochops I pray you get better with that god bless you

[@lesleyshipley8032]

@@drealove9351 hello.. I hope you don’t mind me asking, have you had those red spots since being young? I have - and now I’m wondering about some of my own blood platelets.

[@User-to7nb]

Thank you sir Very cool

[@phanghuilihuili7160]

Can upload a video regarding blast cells?

[@arunmehta8234]

In case of HIT , use of Heparin can cause more damage to patient. Am I right?

[@elviracristobal2806]

I'm a person with ITP diagnosed since I was 3. 😔

[@Zai_Sha123]

Sir I want your help in solving few haenat questions

[@fluffyflo2602]

Mines are at 152 the range is 186 to 353 should i be concerned?

[@lelliateodotova5483]

but how to find out the reason? what tests to make?

[@logaaravindh5863]

Bro discuss about pathology behind hernia

[@jaseemk95]

My platelets count= 15000-20000 Disease :- Thrombocytopenia - 6 I want to know about my disease, Can you make a vedio? Please

[@mabondavis4838]

hello, this is a very informative video.my boss was also suffering from this condition. he visited many hospitals but no one cure this disease. everyone says that this is an incurable disease. but one day he came to know about Planet Ayurveda. he visited there and they gave him an ITP care pack. now my boss is fit and fine.

[@foxfur8327]

Excellent video, thanks, but what kind of specialists should patients be seeing if both red and white platelets are falling very low? Blood specialists?

[@yxi6546]

Hemato-oncologist is the specialist you're looking for

[@theforgottentales3043]

My uncle also suffered from similar problem of low platelets dur to itp. He went from doctor to doctor but of no use until he heard about this Itp care pack from Planet Ayurveda. He used this pack for around two months and results were really good his count went higher than ever since when he suffered from this disease. Then contacted in their clinic and took proper treatment and now he is doing really good

[@pratyushavanya]

Did it really work? Coz I've diagnosed 5yrs ago. My count is below 30k but still I don't have any symptoms

[@marielrodriguez285]

I have this condition and yet we don’t know why!...

[@papawiskas]

I was just diagnosed as well. We have no clue why.

[@debra7449]

If you ever had a vaccine, that is the cause. But they will never say that’s what it’s from. Almost all conditions are caused by vaccines, but they won’t teach you that in medical school. Most doctors don’t know this because they weren’t taught this. But this is why.

[@vickysingha2021]

⚡🌠My platelate not increase from last 1 year due to dangue... ... Total platelate count also less than 1 lakh..... What is the reason sir how I increase ❓

[@sketchie472]

sir mera platelets 190 cout hai sahi hai kia???

[@cristobalanton4122]

i would like to traduce this video into spanish

[@kajal-jz6br]

Plato Plan Capsules by Planet Ayurveda are helpful in elevating Platelet count and improving the shelf life period of Platelets.

[@Jessmetics]

I have ipt. My platelet count at the moment is 70

[@stevenm22]

I am a 31 year old male platelet count has been 80-95, MCV has remained high, and WB is just under normal range for 2 years now just had spleen/liver Ultrasound done normal size. I am being referred to the hematologist (just waiting on them to call to set it all up) whats going on with me?

[@expertisehub987]

ITP

[@travfrmdc]

I’m 14 with low platlets

[@ehex3]

Do you smoke? Do you drink?

[@gregschroer2314]

Sounds like a lymphoma to me

[@quickbiology5159]

It's very fast

[@tgifford4]

Test

[@shivanichhabra1166]

My neighbor's uncle was suffering from ITP from last 4 years, they got very much tired and at last, they came to know about planet Ayurveda, took treatment for 6 months, Now he is perfectly fine

[@shiikae7787]

ANONE ANONE

[@lesjones471]

Why O Why do these people create stupid names like "lThrombocytopaenia" etc yet we have the same item called " platelets "?

[@nikosniko7092]

It comes from Greek words that when is it broken down it describes that issue at hand. Cheers

[@lesjones471]

@@nikosniko7092 Thanks for the reply & demo video.