Top 20 Movie Co-Stars Who Are Best Friends in Real Life

If you bought their chemistry, that's probably because these movie co-stars are best friends in real life. Our countdown includes "Pitch Perfect," Marvel Cinematic Universe, "The Great Gatsby," and more! Who are YOUR favorite real life on-screen best friends? Let us know in the comments!
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MsMojo is a leading producer of reference online video content of Top 10 Lists, Origins, Biographies, Commentary and more on Pop Culture, Celebrity, Movies, Music, TV, Film, Video Games, Politics, News, Comics, Superheroes. Your trusted authority on ranking Pop Culture.

[@jenxevernano]

What about Kate Winslet and Leonardo DiCarpio? They have been friends since Titanic, he has been present at her weddings and she has said that her kids consider him an uncle!!

[@omarrudbergzzz]

Omg yes

[@FantasticBeasts2024]

Plus at each other’s award shows

[@Aster_Risk]

That's really cute.

[@raindropsonroses3919]

He’s also the godfather to one of her kids

[@beccaiskenough17]

Hopefully he doesn’t date her daughter 😭

[@DandyyPlays]

Sisterhood of the traveling pants was one of my favorite coming of age movies growing up and America Ferrera was so important to me seeing a Latina and having her as representation.

[@susiesmith2425]

Alexis bidel is also a Latina

[@DandyyPlays]

@@susiesmith2425 I had to google her bc I forgot who Alexis was (ms Rory herself) and that’s pretty cool!

[@nathalief.1350]

And she is Honduran what makes it better bc we, Hondurans, have very little representation🤧💖

[@isabellamoretti8980]

Love both America and Alexis, but neither are latina. They're americans of latino descent.

[@susanminer2088]

@@susiesmith2425 don’t think so

[@rubygracemoseley8144]

I love that Vanessa and Ashley are friends. Even though they’re kinda rivals in HSM

[@ryanappleton3653]

Vanessa was one of Ashley's bridesmaids.

[@rubygracemoseley8144]

@Ryan Appleton I know! That’s so cute to me!!

[@rubygracemoseley8144]

Wow! I did not expect to get so many likes on this! Cool!

[@kazandeffect2205]

The fact that Adam Sandler and Rob Schneider weren't mentioned is concerning...😒

[@showtimesportsmedia6906]

I mean Adam has so many friends in the business it’s Kind of hard to name just one.

[@kazandeffect2205]

@@showtimesportsmedia6906 True however they've been in 18 movies, been acting together since the 80's/SNL and there was a clause in Rob contract that Adam would make a appearance in his movies. So it's safe to say that Rob is the closest out of all his friends in the industry.

[@dr.kristinedukeawc6799]

Thinking the same thing.

[@sullenboi784]

Sarah michelle gellar and selma blair. They met and co-starred in Cruel Intentions

[@claudialeal9487]

Shannon Doherty too

[@ladyearin]

Let me say. Ian McKellen and Patrick Stewart are the most adorabile duo ever.🥰

[@tvcritics6526]

If Ben Affleck and Matt Damon don't represent bromance, I don't know what does(and also Tobey and Leo)

[@Naruto0s44]

Hell yeah ben wrote damon's movie good will hunting lol

[@Xxmilkshake202xX]

@@Naruto0s44 they wrote it together.

[@ajbrown6687]

A bromance role model is Darren criss and grant gustin

[@tvcritics6526]

@@ajbrown6687 Trueee they are also a pretty good pair

[@bandgeekpoet]

Can't believe Hugh Jackman and Ryan Reynolds aren't on this list!

[@samiicat4073]

Yes, they really should be 😸

[@NixBurkett1984]

and Paul rudd

[@aaccrr78]

Courtney Cox, Jennifer Anniston, and Lisa Kudrow!! Love them.

[@Lovinstories]

Yes, but they are in tv and here it's about movies

[@SushiGurl2002]

Good one, especially only Jen and Courteney, but this is about movies. Guys what about Jen and Adam Sandler?

[@aaccrr78]

@@Lovinstories oh my bad! Totally missed that thanks! Haha

[@michelebrooks3092]

@@SushiGurl2002 id say Drew and Adam instead lol

[@courtneymitchell8439]

That is a TELEVISION friendship. This video was about MOVIE friendships.

[@Aster_Risk]

It makes me so happy to know The Sisterhood of the Traveling Pants actually created a real group of best friends. Their chemistry was fantastic, and it makes the movies more special for me. I was 13 when I read the first book, 14 when I saw the film in theaters and I'm 30 now. I know a book came out a decade ago where the girls were turning 30, so it'd be great to see that kind of reboot.

[@NazriB]

Lies again? Premier League Hugs Kisses

[@hayleydouglas]

You could have Benedict Cumberbatch and Tom Hiddleston from both War Horse and the Marvel Cinematic Universe, they have been friends for 11 years now, and they're both also friends with Eddie Redmayne

[@messsaltos5495]

they were roommates too

[@casckettfriki]

In Pitch Perfect not just the boys became best friends, also the entire Bellas group. They post a lot of pictures on social media together. Just amazing😍

[@JuliaPereira692]

I love Amy Poehler & Tina Fey friendship !!!

[@kscott6378]

I am surprised you guys did not put Justin Timberlake and Jimmy Fallon on the list or Kristen Bell and Mila Kunis.

[@rubygracemoseley8144]

I love The Sisterhood of Traveling Pants and I love that those actors are best friends in real life! I mean it makes sense. They all had such realistic great chemistry in the movies

[@pedropelaez]

Not sure about the janes Franco and Seth Rogen being friends anymore after rogen says he won’t work with Franco again because of sexual assault allegations. .🤷‍♂️🤷‍♂️

[@shannoncopeland4506]

That's what I was thinking. I thought for sure there would be lots of comments about that, but yours is the first I've found.

[@FantasticBeasts2024]

Where is: Kate & Leo?! Emma Watson & Tom Felton?! Helena Bonham Carter & Johnny Depp?! Glee cast Harry Potter cast Love: Cameron Diaz & Drew Barrymore 💓 Sisterhood of the Travelling Pants girls❣️ Seth & James - comedic duo 💜 Tina & Amy - comedic duo ♥️ Simon Pegg & Nick Frost - comedic duo ❤️ Matt Damon & Ben Affleck 💖

[@iamgroot2810]

Anthony Mackie and Sebastian Stan's friendship makes me so happy.

[@MomLifewithKristen]

Aw you missed Adam Sandler, Kevin James, Rob Snider, & David Spade! I feel like they always doing movies together because of their friendships!

[@nighttripper18]

And Chris Rock :)

[@kiaraeijo]

It’s true though

[@catrina718]

Really, no Eddie Murphy and Arsenio Hall? They should be on your mind again given that Coming 2 America was just the #1 movie in America.

[@christ512]

wait so you're telling me both the old and new Xavier and Magneto are BFFs?

[@sophiaackley3535]

Don't you just LOVE that? ♡♡♡

[@jessesanchez9187]

Kate Denning and Natalie Portman. Kate reported that they have been friends for years. She was reading for a part on Thor. Natalie came in, and sat on her lap. The producers saw so much chemistry between the two that they expanded Dennings role.

[@lucifermorningstarwishesyo2607]

Kat Dennings*

[@bronnieo4880]

Kat Denning also knits with Rhonda Rousey have been friends for years

[@rhondawomble9036]

Octavia Spencer and Melissa McCarthy, they have been the best of friends, long before either one was famous. Gwyneth Paltro and Maya Rudolph have also been best friends since they were seven years old.

[@sridipa]

How about Chris Evans and Scarlet Johansson??!!

[@gabrielleferraro6275]

Your forgot: Oscar Isaac and Pedro Pascal Hugh Jackman and Ryan Reynolds

[@Xxmilkshake202xX]

They missed a lot. Leo and Kate Adam Sandler, Rob Schneider, Chris Rock Johnny Deep and Winona Ryder

[@Mos41f]

Bryan Cranston & Aaron Paul, Leonardo DiCaprio & Kate Winslet.

[@GentlemanGaGa29]

Cranston and Paul were never in a movie together, are you even sure they're best friends?

[@Liv-hx9xx]

No Chris evans and Scarlett johansson???

[@slime_sznnn1913]

Right

[@faboul467]

Ironic how rivals in movies are best friends in real life whereas best friends and or lovers in movies are rivals in real life.

[@kiaraeijo]

There are many other bffs that they forgot about: Carol Burnett and Julie Andrews, Kate Winslet and Leonardo DiCaprio, Robin Williams and Billy Crystal, Adam Sandler and Rob Schneider and Jane Fonda, Dolly Parton and Lily Tomlin.

[@Aster_Risk]

Whoopi Goldberg is actually the third part of the Robin Williams and Billy Crystal friendship triangle.

[@MadisonC]

Ahhhhh Chris Hemsworth’s and Tom Hiddleston’s friendship is too cute my hearttt

[@arianna4513]

i love how Vanessa and Ashley are still best friends to this day, its so adorable

[@passiveagressive4983]

What about Busy Phillips and Michelle Williams

[@michelleflood7225]

What about jake Gyllenhaal and Heath ledger for heavens sake jake is godfather to heaths daughter Matilda !

[@froppygurl07]

What about Ben Stiller and Chris Rock? They were friends in and off screen for Madagascar and it's great :D

[@Adri.annaa98]

Mila Kunis & Kristen Bell are best friends as well as their husbands 🥺✨

[@SallySkellington84]

You totally forgot kate winslet and leo! I want to be friends with Woody and Matthew! I can see the fun that could be had!!

[@dafilmqueen556]

Michael Fassbender isn't the only costar James McAvoy is friends with in real life. You have Jessica Chastain as well,and he also got enough chemistry to work well with other costars like Bill Hader and the rest of the IT cast(the teen and adult casts alike are also buddies in real life). But if they are all friends in real life,then Michael is James' bestest friend ever.👍

[@LvBMusik]

What about Jennifer Aniston, Courteney Cox, and Lisa Kudrow??

[@jeremyking9986]

Movies

[@LvBMusik]

@@jeremyking9986 🤦‍♀️ You’re right. That’s embarrassing.

[@asbaran]

So...we're just gonna ignore that X-Men: First Class was mentioned as X-Men: Beginnings in this video?

[@emilyruballos919]

You missed Tom Holland, Zendaya, and Jacob Batalon they’re besties

[@jassyjones]

Corbin bleu and Monique Coleman are also friends in real life they even went on double date together and Jennifer Lawrence, Josh hutcherson with Liam Hemsworth

[@chefshen1631]

I think we need a reunion of the sisterhood of the traveling pants

[@dawnjensen6560]

As a Jersey girl I am pissed to not see Kevin Smith and Jason Mews on this list.

[@basubenburns]

How did you miss Sarah Michelle Gellar and Selma Blair?🤔

[@Sofia-qn6fs]

Leonard and Tobey my all time favourite ❤️

[@trinaq]

Mine too, I love how close they are off camera! 💕

[@biseyoum2571]

What about Adam Sandler and Kevin James? 🤔

[@sacredjules]

HOW CAN YOU SKIP HUGH JACKMAN AND RYAN REYNOLDS?!

[@aaronwolk998]

Dave Franco and Seth Rogan didn't hold up as well as they predicted I guess.

[@angelas8644]

Jennifer Lawrence and Josh Hutcherson! I can’t believe these two were left out.

[@petraoconnor5085]

What about josh hutcherson and Jennifer Lawrence?

[@michelebrooks3092]

That James Franco one didn't age well did it 😂

[@courtneymitchell8439]

Although half of each duo has passed away you forgot Paul Walker and Vin Diesel and Heath Ledger and Jake Gyllenhaal.

[@genius179]

You guys should’ve included in Girls Trip, there’s a line where someone says “Let’s set it Off” and Jada and Queen Latifah look at each other

[@Naruto0s44]

Lmao that was great

[@khaniyah1494]

Exactly. Was thinking the same thing

[@genius179]

@@khaniyah1494 my dad pointed it out to me like the 2nd time we watched it because I didn't pick it up

[@khaniyah1494]

@@genius179 I was only hoping they would reference set it off. Movie is such a classic

[@genius179]

@@khaniyah1494 You are so right, great ensemble cast, and I say this in the most respectful way because it meant she was doing a great job, Queen Latifah as Cleo was absolutely terrifying. Like the other ladies, it felt like society had them with the backs against the wall to rob, Cleo would want to rob or commit crimes even if she was a millionaire ten times over. The mannerisms she had, body language, scowling. Queen was excellent in that movie and she's more of an actress for dramas rather than comedy but Hollywood you know how they are. . .

[@spikeluv84]

You left out the best recent discovery about Matt and Ben! They're actually distant cousins!

[@mariabalcan5260]

Emma Stone and Jennifer Lawrence hahahah ❤❤❤

[@jeaustinnunez3839]

Top 10 Worst Total Drama Rivalries (#1 Gwen and Heather, of course)

[@shannonschmitt7443]

I really wish they would have included the LOTR cast, especially the actors who played the 4 hobbits! They are all still super close to this day and are always meeting up and posting pics together. They’re freaking adorable lol

[@trinitygirl3716]

Diego Luna & Gael García Bernal

[@julierigal595]

Chris Evans & ScarJo / RDJ

[@agent_w.]

wholesome friendships

[@trinaq]

I agree, I love how pure all of these friendships are! 💜

[@aesquivel287]

Where’s Leo and Kate ?

[@queenredfromthequeencity]

I don't think you know what best friends mean, as suppose to just being friends.

[@Disney65Fan]

Jojo,Emma Roberts and Sara Paxton Aquamarine Kevin Hart and Dwanye Johnson- Central Intelligence Ben Stiller and Owen Wilson- Meet The Parents Drew Barrymore and Adam Sandler- 50 First Dates. Others Tobey Maguire and Leonardo DiCaprio Leonardo DiCaprio and Kate Winslet

[@larisalynnortiz8979]

Wow, Ben Stiller and Owen Wilson!

[@analuciagarciaulloa5161]

Where's Hugh Jackman and Ryan Reynolds?!!!!

[@kaittieblanco7907]

Seth just dumped James so kinda weird to see them on this list.

[@AlexandelHowl]

Sarah Michelle Gellar and Selma Blair.

[@alanahaye5637]

I haven't watched it yet but please tell me the Friends cast are somewhere in here They've been friends since like forever

[@ashleyhannigan505]

This is just movies, no TV shows.

[@kharma7755]

Lisa Kudrow and Mira Sorvino are still besties after working together on Romy & Michelle's High School Reunion

[@anonymouse755]

This video should have included a clip of Ben Affleck sneaking Matt Damon onto the jimmy Kimmel show... that was hilarious

[@ashleydowney1222]

Vanessa Hudgens has never been married.

[@vornicuandrei5764]

Ryan Reynolds & Hugh Jackman ??? The coolest guys in the Universe. I was expecting them to be no.1

[@laurenmariehutton]

Where's Adam Sandler And Rob Schneider? Leonardo DiCaprio And Kate Winslet? Tom Felton And Daniel Radcliffe? Daniel Radcliffe And Emma Watson? Dakota Fanning And Kristen Stewart?

[@riderj123]

Do Top 10 or 20 TV co stars who are best friends in real life, please? Sophie Turner and Maisie Williams should be on the list

[@noemisternenkind]

And Ian Somerhalder and Paul Wesley!

[@Arryxavenues]

They left tv stars out

[@veemonfan8102]

17:04 Wait, Leonardo Di Capprio could've been the ORIGINAL SPIDER-MAN?!🤯

[@NixBurkett1984]

I'd have put Jonah Hill and Jay Baruchel in with Seth and James. the Pitch Perfect Bella's Robert Downey Jnr and Johnny Depp Vin Diesel and Paul Walker Hugh Jackman, Ryan Reynolds and Paul Rudd Chris Evans and Scarlet Johansson Robert Downey Jnr and Gwyneth Paltrow Sandra Bullock and Melissa McCarthy Adam Devine and Rebel Wilson Zac Efron and Zendaya Zac Efron and Dave Franco Adam Devine and Zac Efron Eddie Redmayne, Andrew Garfield, Robert Pattinson and Jamie Dornan

[@patrickkelliher9962]

Nicole Kidman and Naomi Watts.

[@noemiarmas5773]

America Ferrera And Blake Lively Stanuida In Love Edit Black Mamba AESPA Sebastian Stan And Claudia Kim

[@kate1812]

Kate Winslet and Leonardo Dicaprio

[@thinadlamini4671]

You forgot to add Nicole Kidman Naomi Watts they became friends in 1991... oh and Keira Knightley and Natalie Portman.

[@neilburns8869]

Damon is also very good friends with both Clooney and Pitt, and I guess you could probably throw both Affleck brothers in there as well.

[@TheSmpsnsG85]

Chris Farley and David Spade!

[@anujasodagar]

Sooo the Xmen franchise churned out two sets of bffs, both sets playing the younger & older version of Prof X & Magnito?! 🤯🤯

[@TheFireBurningWithin]

disappointed to you didn't include any of the big friendships of different genders eg, kate Winslet and Leonardo DiCaprio as well as Jeremy Renner and Scarlet Johannson.

[@angelasettles4201]

Brie Larson and Samuel L Jackson

[@NickCC23]

Gina Gershon and Jennifer Tilly met making Bound. Nearly a quarter century on they are still good friends. Also Jack Lemmon and Walter Matthau were as strong as any mentioned.

[@mi3ki]

also kirsten wiig and maya rudolph

[@candyb2205]

I would've swapped number 2 and number 3. Sir Ian and Sir Patrick are super cute and only Matt and Ben are more iconic ❤️

[@londiwehlongwe8842]

Sir Ian and Sir Patrick are actually engaged

[@danillewilliams4816]

....u left out ben stiller and Owen wilson....

[@trinielenam0314]

i was really just waiting for leo and tobey ♥️

[@rsairar]

What about Ben Stiller and Owen Wilson?! They deserve an honorable mention at least.

[@GreenKnight1982]

I am not at all surprised about Sir Ian McKellen and Sir Patrick Stewart being friends! Considering how high of a caliber of actors they are they seem like they would be good friends. And the last one is a no sh moment

[@nikwalters1029]

Ummm Robin Williams and Billy Crystal? Kevin Smith and Jason Mewes? A rare siting of male/female friendship in Leo and Kate?

[@via1968]

Ian McKellen and Patrick Stewart, Michael Fassbender and James McAvoy. who ever will be the next Xavier and Magneto I hope they become BFF too!

[@amandaredd3057]

I've been with my best friend for 35 years and I can definitely agree that you develop that type of report and connection. You get to where you already know what the other thinks and don't always have to voice your feelings. It's wonderful and I know I cherish my friendship.

[@judithblanken9705]

Supernatural Jensen Ackles & Jared Padalecki for me.

[@taylorwatts9391]

I tell you movie costars who are bffs in real life that did not make the list: Kaitlyn Dever & Beanie Feldstein from Booksmart. I know they support each other with the things they star in like movies and tv shows, go live on insta & share memories of their movie.

[@cassiebella314]

What about Dominic Monaghan and Billy Boyd? They created a podcast together literally called The Friendship Onion...if that's not BFF status I don't know what is lol

[@badboy-kr6dq]

I read recently that rogen is distancing himself from franco over some things said and done by franco.

[@masonplacher7096]

Request: top 10 titles that should stream on Disney plus (King of the hill, Bear in the big blue house, and Deadpool [I know Deadpool is for mature audiences and doesn’t exactly suit Disney’s family oriented reputation, but a Marvel movie is a Marvel movie]) plus a few honorable mentions.

[@AKASH1167]

OMG....MSMOJO......THIS IS WHY I LOVE U SOOOOOOO MUCH...... THANKS A LOT.....THIS VIDEO ALONE JUST MADE MY DAY........ ❤️❤️❤️❤️❤️😘😘😘😘😘