TOPAZ-1: 3-year survival, eLTS & safety of durvalumab and chemotherapy in BTC

Do-Youn Oh, MD, PhD, Seoul National University College of Medicine, Seoul, South Korea, discusses the updated 3-year survival, extended long-term survival (eLTS), and safety results from the Phase III TOPAZ-1 study (NCT03875235) in advanced biliary tract cancer (BTC). The study compared durvalumab with gemcitabine and cisplatin against placebo with gemcitabine and cisplatin . After a median follow-up of 41.3 months significant long-term survival benefits with manageable safety were observed in patients receiving durvalumab. This interview took place at 2024 European Society for Medical Oncology (ESMO) Gastrointestinal Cancers Annual Congress in Munich, Germany.
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