Triple-Negative Breast Cancer: Everything You Need to Know

What is triple-negative breast cancer and what are the treatment options? In this video, Dr. Jennifer Griggs provides a comprehensive guide and explains everything you need to know about triple-negative breast cancer.
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[@user-rk4ks7ok3m]

Thank you so, so very much for that information. I am a black woman and I go my first diagnosis of triple negative breast cancer at age 36. I have a family history of ovarian, prostate and breast cancers. I live in Barbados. So this helps me to understand this much better. I've had 2 recurrences since first being diagnosed in 2019.

[@juaquiene7726]

Dear User from Barbados' I used to get bent. That you'd be urged to reveal your race. While filling out medical forms. I wondered why was that information so important? I angrily thought, are they being nosey, perhaps even racist? I'd even refuse to fill in that question. For that reason. As we move along, through this ( cough-cough) Journey of breast cancer. You become aware just how important the role of our genetics plays. Not just by our family. But our race as well. The big question is why is triple negative. Seen more often amongst black ladies? It becomes obvious there be a specific genetic marker. Certain kinds of cancers tend to develop with. This information. May end up playing a role in treatments. & we can pray eventually a cure. For this aggressive type 😢of cancer. Barbado's lady your story cut right to the point. For now you of course can warn the women in your family. But to all young black women. To routinely examine ones breasts. Get those yearly mammogram's done. You'll be in my thoughts and prayers I sure hope they can stop your cancer spread.

[@yerbba]

We're really glad the information was helpful to you. Facing triple-negative breast cancer, especially with recurrences, is incredibly challenging. Black women are at higher risk of triple-negative breast cancer, which is unfair on so many levels. Thank you for watching.

[@naththomas9946]

Thank you, Dr. Griggs, for your continuous support of breast cancer (health) and awareness.

[@yerbba]

Thank you for supporting our channel!

[@ritaeckert4766]

I was successfully treated for TNBC in 2023. I had a lumpectomy that successfully removed the remaining tumor. However the side effects of the treatment has been horrendous! Keytruda caused immune responses that affected my urinary system that took months to figure out was the cause of cystitis, incontinence, blocked ureter, and lots of pain. The only treatment has been steroids but the symptoms all come back once I’ve tapered down. Additionally, the capecitabine caused hand-foot syndrome that I am still struggling with. While I did not notice any CIPN at the beginning of chemo, it certainly set in once I was just taking the 2 meds mentioned. I finally refused to take anymore of either med last December. A 2nd opinion from another oncology group agreed that I should not take either drug any longer since my side effects were so bad, my tumor try shrunk so small & they know they got it all. My lymph nodes were also clear. While I’m feeling so blessed to be ‘cancer free’ dealing with these other issues are a struggle and it’s been very depressing. I’ve been told both reactions are rare & wonder if anyone else is experiencing them? It’s been ongoing…..

[@yerbba]

Thank you for sharing your story with the Yerbba community. You have had a really rough time for sure. The hope is that you'll recover from all these side effects. Some people have a stronger reaction to anti-cancer drugs. These are not the same people who are sensitive to antibiotics or other commonly-used drugs, so it's hard to know if someone will have a reaction or reactions such as you have. Many people think that immunotherapy is less toxic than "traditional" chemotherapy, but when side effects happen, they can be really hard to deal with. Wishing you the best as your healing continues.

[@mariascarpato2400]

Thank you Doctor! 💕

[@yerbba]

Thank you for being part of the Yerbba community!

[@kellileung6741]

Thank you

[@yerbba]

Thank you for watching!

[@cynthiayee5116]

Greetings Doctor ,.Please make a video on Tripple positive Breast cancer .

[@yerbba]

Thanks for writing. We have a video on triple-positive breast cancer here: kzbin.info/www/bejne/ZnOmmJSIoJl0ftk

[@raju-nd9bd]

Hi Doctor , this is very helpful video especially the point you made that TNBC will not be gone completely with Chemo therapy which is big awareness for us . Can you please some put lights on latest advancement/research happening for TNBC for stage 4 disease or recurrence of disease ?

[@yerbba]

Thanks for writing. There are a lot of newer treatments for Stage IV (4) triple-negative breast cancer. The options for treatment depend on several different factors, including whether the patient has a BRCA mutation, whether the tumor has a PDL-1 protein expression, and the previous treatments that were received.

[@paigemckelvey8781]

This explanation for TNBC points out what it is and what it is not . Is there any further classification when pathological findings are done when the tumour is removed and closley examined? I had TNBC with two different rounds of (2 drugs each) Keytruda, surgery and radiation. There was no evidence that chemo stopped the growth of the tumour. Spindle cell was determined to be present in the biopsy. As always, your videos are presented so well. Thank you for all your time and efforts

[@yerbba]

The most common test performed in people with TNBC is PD-L1. In people with advanced disease, immunotherapy like pembrolizumab (brand name: Keytruda) can be given to people whose tumor has PD-L1. The other test that is done, usually with a patient blood test, is BRCA1/2.

[@rodelengicaro6999]

I was diagnosed trippple breast CA last june of 2023 done 8 sessions of chemotherapy February 2024 had my surgery mastectomy unilateral with sentinal march 27 2024 then lympnodes dissection .level 1 and 2 .just last mAy 1 this year. i will have my follow up on 16th of May for the pathology report from my lympnodes and then they will decide what the next treatment i will undergo. I just want to say your channel adds more information about my case . With more prayers 🙌 healing is our hearts desire. As a breast cancer warrior.

[@shubhammali2281]

My sister has been suffering from triple-negative breast cancer for two years. After this period of treatment, I have learned that there is only a 10% chance of survival for people with this condition.

[@yerbba]

Thank you for sharing your journey with us. It sounds like you’ve been through a lot, and we admire your strength and determination. We're glad to hear that our channel has provided you with additional information and support. Continued prayers for your healing and positive results from your upcoming pathology report.