Trisomy | Down's vs Edward's vs Patau's Syndrome

A trisomy is a type of polysomy in which there are three instances of a particular chromosome, instead of the normal two.[1] A trisomy is a type of aneuploidy (an abnormal number of chromosomes).
The most common types of autosomal trisomy that survive to birth in humans are:
Trisomy 21 (Down syndrome)
Trisomy 18 (Edwards syndrome)
Trisomy 13 (Patau syndrome)
Trisomy 9
Trisomy 8 (Warkany syndrome 2)
Of these, Trisomy 21 and Trisomy 18 are the most common. In rare cases, a fetus with Trisomy 13 can survive, giving rise to Patau syndrome. Autosomal trisomy can be associated with birth defects, intellectual disability and shortened life expectancy.
Here we will also see what are the differences between Down's Syndrome , Edward's Syndrome and Patau's Syndrome.
Why Down's Syndrome is more frequent and why Patau's Syndrome is very rare ?
Find out in this video.

[@gracechi4469]

Put Three Trisomy together in one lecture, no other better way to make the clear and easy understanding of the characters.

[@hussainbiology]

Thanks Grace for appreciation....Glad to know that it helps

[@rajoasis6476]

@@hussainbiology à

[@kaurchadha]

very concise and to the point. Great job on putting a perfect picture of three polysomy.

[@ChiTownsFinest1225]

Awesome video. Thank you for explaining it so clearly. I learned a lot just now. Keep up the great work! I'm so happy I found your channel!

[@hussainbiology]

Thanks Nicole for appreciation.. Really Glad to know that it helps....😊😊

[@syphoresdrow5077]

man this is incredible , thanks a lot and keep doing more

[@hussainbiology]

Thanks for appreciation.....Glad to know that it helps

[@sherronbrown4482]

EXCELLENT explanation! This was really helpful. My professor is so impressed with me! Thanks to YOU!

[@hussainbiology]

Thanks for appreciation..Glad to know that it helps ✌️

[@fernemcallister6774]

Best and clearest explanation. Thank you.

[@hussainbiology]

thanks for appreciation

[@Aa-ji2yf]

Very good explanation. Thank you.

[@Ajaykumar-iv4sc]

Thanks for more clearity

[@trishayamada807]

I didn’t know I needed to know this, but I found it fascinating. Thank you for the easy to understand explanations.

[@hussainbiology]

thanks Trisha for appreciation

[@trishayamada807]

@@hussainbiology my daughter was born with a fused skull suture. I gave the medical scientists permission to use her DNA. They don’t get many people to donate but I did because I hope what they can learn from her DNA can help other people.

[@hussainbiology]

@@trishayamada807 Oh Great... It is very rare now a days to contribute for a Medical cause that too when u had to out forward your daughter.... Commendable..♥️

[@trishayamada807]

@@hussainbiology I sincerely want to help and to give back to society. If people had not donated blood and plasma my baby would have died. They are my heroes and I will never know their names.

[@hussainbiology]

@@trishayamada807The Almighty has bestowed u with lot of strength ....❤️❤️

[@lhingpichongchongloi8941]

It really helps me,its clear and easy to understand.Thanks so much👍👍👍

[@hussainbiology]

thanks for appreciation

[@shahabuddin6149]

Great work sir,thanks alote

[@rukhsaryusuf4432]

this video is wow. i mean we always went with theory but not with the comparison in this case .thank you

[@hussainbiology]

Thanks Rukhsar for appreciation...Glad to know that it helps

[@poornimakamble9565]

Thank you sir this was so simple explanation.. which I got and easy to understand.. thank you

[@aynalsaba7982]

well done Shabir👍

[@hussainbiology]

Thanks Saba for appreciation...

[@anishpalx-a-0273]

Please make a video on Turner and klinefelter syndrome

[@alyafei1997]

Thank you so much!

[@hussainbiology]

thanks Aliya for appreciation✌️✌️

[@rahulredgram]

Very nice learned very new facts

[@gracechi4469]

Thank you so much.

[@hussainbiology]

Thanks Grace for appreciation.....

[@kathleentempelaar3017]

Thank you very helpful

[@hussainbiology]

thanks for appreciation

[@shameenak.m6929]

superb need more videos like this

[@hussainbiology]

InshaAllah

[@jennifersaar1611]

Great lecture - very clear and concise. The mechanics of trisomy are fascinating, but the results are tragic.

[@hussainbiology]

thanks for appreciation...

[@najmasayeed3687]

@@hussainbiology w wzz , ,, ,

[@hussainbiology]

@@najmasayeed3687 wwzz ???

[@SteveNinetyski]

Thank you. My partner and I had a miscarriage at 14 weeks with Patau syndrome:(

[@allamalik4209]

Thank u really helpfull

[@hussainbiology]

thanks for appreciation..Glad to know that it helps

[@ranipa3576]

Thank you 🤗🤗

[@hussainbiology]

You are welcome

[@sandrasilver4554]

Some are born teachers.You are one of those.I am a doctor and 64,struggled to understand this.simply explained.When we order NIP test should the parents get pre genetic test counselling.

[@angelinamonderin4392]

Thank you for explaination.. my result test is 1:477 is it okay or not?

[@doctorofmedicine1113]

i have no words for this lecture... Roz hs tayaar ....paga Jinduu match....

[@nelafer.s3368]

My age is 20..I'm 5 months pregnant for me risk of t21 is 1:300 is it normal?

[@rammurtiswami5167]

Hi enaku trisomy18 test in normal low risk baby ku any problems pls reply sir

[@monjushreeadhikari624]

Sir,,my age is 36 and my trisomy 21 result is 1:113. Is it risky?? And what to do

[@carlazpm]

My baby had trisomy 7, can this happen again in my future pregnancies, i had 3 previous healthy pregnancies but by my ex. It mentioned also something about a twin could not be ruled out

[@hussainbiology]

Recurrence is pretty rare less than one percent.

[@monalishaparida5650]

Hello Sir.. My age is 30..I am 5th month pregenet..My T21 in tripple marker test is 1:715..is it normal.. My doctor said that it is intermediate risk..Now I'm in very much tension..plz advice me what should I do now??

[@tapatighosal6381]

Ma'am aap aur baby thik ho?

[@sujatharajukethavath4562]

Sir we got in double marker test in that we got the down syndrome value is 1:850 Papp-a 0.40 mom Regerding to this values any problems please give me your suggestions sir

[@shilpareddy90]

Can you please tell me is everything alright?

[@due0yu_GGucci]

Do you have any video on Cri du chat (cat cry) syndrome?

[@hussainbiology]

No dear , it is yet to be made.

[@emmamaystirton2789]

I had a daughter maci who had Edward's, I wishing had Know what I know now,as at 8 days old her life support was switched off n if I'd known what I know now I wouldn't have done that,I never got told anything I'm so mad

[@hussainbiology]

God Bless u and give u strength at times...

[@asmitahirapara5505]

In my report there is a high risk of trisomy 21, it is big problem gor my baby??

[@shilpareddy90]

Hello... same has happened with me... can you please update about your baby?

[@mkeditsversion7402]

Hi, Trisomy 21 st chromosomes By age risk 1:1278 Final tr2 1:95 NT scan and 19th week anomaly scan all normal.. Is it normal or risk

[@boomabooms437]

Hlo sis what happened now?

[@rafaqatrehman3883]

Best lecturer __Maastrr boii pnun

[@hussainbiology]

Shukriya boi,,,,,,,

[@twinsvvstar2615]

Please describe in hindi

[@biology_mcqs3037]

Oh I'm late 🏃💨

[@abhaykadam1200]

My baby was detected by trisomy 18. Now baby is no more. What precautions should be taken for pregnancy? Please guide me.

[@hussainbiology]

Nothing.....This is random

[@jmk1962]

It's not always random. I lost 4 babies. Two miscarriages at 8 and 12 weeks. Then lost a fullterm baby, 3 days past her due date. She weighed just under 8lbs (3.6kgs) and the post mortem could not find anything wrong with her so they put her death down to cot death, but in the womb. Then a year later I had a son, born by elective caesarean section at 37 weeks because he was breech and they didn't want me to go fullterm because of what happened to his sister. I knew from birth that he wasn't right but no one would listen to me. Six different doctors checked him out before leaving hospital and none of them spotted anything wrong with him. My health visitor dismissed my concerns when I raised that he wasn't meeting his milestones like smiling at 6 weeks. She said he was early, he'll be a bit behind, stop worrying, and eventually I had to keep my concerns to myself because I was afraid they would think I had post natal depression. Then one day when he was 5.5 months old and had a cold I noticed his breathing looked quite laboured and my motherly instincts once again made me concerned that he wasn't looking right so I decided to take him to the baby clinic for a check up. We left home and when I glanced down at him in his car seat and he had turned purple. Long story short, he was rushed to our local hospital where they worked on him for 5 hours before transferring him to St. Thomas's Hospital in London where they worked on him for a further 5 hours before coming to us to tell us there was no more they could do. They said they would phone GOSH, Great Ormond Street Hospital, to see if they has a bed and fortunately they did. Within 45 minutes GoSH had him intubated and they put him into a medical coma for 10 days to let his body recover. Then he was transferred to a respiratory ward where the genetics team came to look at him and they took some bloods. A week later we were called into a meeting where they told us our son had a rare form of Edwards Syndrome/Trisomy 18. They told us they only knew of 6 other babies in the world who had this particular form of Trisomy 18. Of the 6, 5 died between 6-8 months and only one lived until 13 months. They told us he would never walk or talk and that he would have no quality of life and to take him home and expect him to die at any time. They were that blunt. Our son lived quite happily for another 10 months. He was never in any pain, was not on any medication apart from a food supplement. He hated his NG feeding tube and pulled it out so many times they left it out as he was doing so well with his Haberman bottle. He loved his music classes and was at his happiest when he was at special needs swimming submerged in the warm water where he was so relaxed he used to sing to himself. He was a complete joy to be around and was surrounded by love as everyone who ever met him adored him. Sadly the doctors were right and after he had an epiletic type seizure one night, his heart stopped 3 weeks later and he passed away. Our little soldier was off to join the angels to be with his siblings. We had spent 10 years trying to have and losing babies and no doctor had ever suggested genetic testing for us during this time just telling us we were unlucky. Our sons geneticist asked us after our son was diagnosed, if we would like to be tested and we said yes as we were looking for answers and we found out that my husband was a carrier of this condition although he was not affected by it. So a simple blood test could have saved us from 10 years of heartache. Having said this, I do not regret a single day of the time we got to spend with our gorgeous son, but I now say to any couple who are having repeated miscarriages or stillbirths to ask for genetic testing because healthy babies do not just simply die. I believe a lot of cot deaths are down to undiagnosed genetic conditions. I just wish doctors were more understanding and more forthcoming and that they would listen to mothers concerns and take them more seriously as no one knows their child better than the woman who has grown them inside her for 9 months. Never ignore a mothers instincts when she says her child is not right. Hope this helps others to push for genetic testing

[@cottxncaxdy345]

@@jmk1962 Thanks for sharing your story. I am so sorry. I really feel you cause i went through what you have been through. I have lost total of 4 babies. Two miscarriages and two was born a live. One was two days old with Trisomy 18 and the other one was two months old with Trisomy 13. It was the most darkest days in my life when I lost my babies to these horrible diseases. I have been pushed off by the doctors when I ask them, if this can be genetic issues. Their answers, “ No. It’s just a random thing”. It was 2019 when I lost my last baby. I still suffer to the point that I am scare to get pregnant. Please let me know which test should I ask them to do. Again I am so sorry about your babies. God bless you!

[@jmk1962]

@@cottxncaxdy345 - Hi, so sorry for the loss of your babies. Hugs to you it is a horrible time and not knowing why is the worst thing. Your story is so similar to mine, but what shocks me is that this is still happening in 2019 as I lost my two last babies in 1998 and 1999 so I am shocked to hear that doctors are still not doing genetic testing 22 years on. You should insist on speaking to a geneticist. With your history of losing 4 babies, one to Edwards and one to Patau's I would say that is a definate cause to do genetic testing on both yourself and your partner, as the chances are one of you is a carrier like my husband was. It is just a simple blood test where they look for markers and when they know what they are looking for it makes it even easier for them to do it to rule it in or out. Saying it is just a 'random' thing and that you've just been unlucky is not acceptable as you have lost 4 babies already, two with recognised genetic conditions, that's not random under any circumstances and you need to know to prevent further heartache. A good geneticist should support you with this. I don't know where you're based, but have you heard of the charity S.O.F.T? It's a charity that supports families of babies who have Trisomy 18 & 13. They have geneticists who work with them who are most helpful and they have loads of information on their website, although the stories of the babies can be heartbreaking, especially as your losses were so recent. www.sort.org.uk Do ask to speak to your local geneticist and insist on yourself and your partner being tested because if you don't you will never know and I do understand your fear of becoming pregnant again in case the same happens. A blood test could confirm if one of you is a carrier. If it is your partner, then you could consider other options like donor sperm, or if it is you than maybe you could look at adoption. There are always other options, but if you are not tested you will never know for sure and that is worse than knowing IMO. We did go on to adopt two daughters 2 years after our son died as we were both 40 and really wanted to be parents. It's not an easy process but is so worth it. Wishing you all the luck in the world from someone who had been where you are. xx

[@Sadaf239]

👍👍👍

[@aiyannaespinoza5448]

What about trisomy 9 explain that.

[@hussainbiology]

Hi..That trisomy is very rare that is why i haven't discussed it here...

[@tumharahelper7938]

Kashur 👍

[@hussainbiology]

bilkul

[@tumharahelper7938]

@@hussainbiology mainay pronunciation se hi pehchan liya , me too "kashur" ❤️ from reasi.

[@ansarneesha2033]

My age is 33. I am 4 month pregnant. For me risk of T 21 is 1:987 is it normal?

[@hussainbiology]

it is absolutely normal... Sorry for being late

[@ansarneesha2033]

Thank you sir. Really normal. But my doctor suggested NIPT test. I am so scared sir.

[@hussainbiology]

@@ansarneesha2033 If doctors have advised then u should go for it... It is simple test and risk free...... ( But why doctors have advised ??) do u have any genetic history of chromosomal abnormalities??

[@ansarneesha2033]

Ok sir. Thank you

[@hussainbiology]

@@ansarneesha2033 most welcome......Allah bless u

[@wendywardashley]

Would be nice if you spelt LETHAL correctly.

[@vinayprakash9647]

Osssmmm sir love from India🇮🇳🇮🇳🇮🇳

[@hussainbiology]

👍✌️✌️

[@Linasrecovery]

This random guy is better at teaching than My professor

[@hussainbiology]

thanks buddy for appreciation..Glad to know that it helps

[@hmmm7586]

leethal💀