Using 3D in vitro tumoroids for personalized medicine

Presented By: Marilena Loizidou
Speaker Biography: Marilena Loizidou is Deputy Director of the Division of Surgery and Interventional Science, Head of Department of Surgical Biotechnology and a Professor of Cancer Nanotechnology at University College London (UCL).
Webinar: Using 3D in vitro tumoroids for personalized medicine
Webinar Abstract: Tissue samples can vary in extracellular matrix (ECM) composition, cell heterogeneity, and rigidity. Consequently, dissociation approaches require extensive optimization and care, as improperly disaggregated samples can reduce cell viability, decrease the efficiency of cell compartmentalization and block downstream instrumentation. The isolation process involves tissue dissection, mechanical dissociation, and enzymatic breakdown of the ECM. There is a clear need for tissue dissociation systems for researchers to standardize the digestion and disaggregation of solid tissues samples to consistently obtain high quality, viable cells.