USMLE® Step 1 High Yield: Nephrology: Renal Tubular Acidosis

[@ilovebeinagirl]

5:55 Type 1 RTA 8:03: Type 2 RTA 7:23: Type 4 RTA

[@Toxicperson700]

Thank you so much

[@ammadbinilyas6309]

best single video to understand whole kidney electrolyte hemostasis function

[@Doinmabestt]

i never imagined I'd love RTA thank you, 9 years and still best explanation

[@fatimahtahir4727]

Best video so far

[@kaplanmedical]

Glad this video was helpful! Send us a DM on Facebook, Twitter, or Instagram if you have any questions or need help with your USMLE prep. We've got your back! -Kendra

[@bharathiraja3233]

awesome man... i got so much confused with this section... after visualizing i can see clearly... thak u so much for this.... please do more videos like this...

[@mohamadelzaim6218]

Best explanation I have come across.

[@daniloboskovic8083]

for nephron function too :) only thing missing is substrate/Na symproters at luminal side of the membrane (increase concentration of Na in the cell and enable better function of Na/K atp-ase, which is also required for the symporter to work) and substrate uniporters at basolateral side of the membrane.

[@gavaskarsachin7532]

great animation and explanation... thank u guys....

[@RidleyE]

Other than that 1 error with sodium, one of the best videos out there on the subject. Thank you.

[@umerkhan7545]

RidleyE what mistake

[@umerkhan7545]

RidleyE where is the error with sodium

[@spirulinachlorella1629]

best explanation of the whole fckin internet! you are great, guys! is there homepage or something, where is more stuff like this to find???

[@lam7624]

Thank you so much you just make it more clear

[@aprikosrussin]

Hi, nice video :) But why is sodium charged (+2)?

[@eyal9654]

My guess is that he probably took his calcium atom template and just switched C with N (to save the time of having to make another molecule with whatever program he's using to animate) and forgot to change the charge

[@فجرالشام-ق7ك]

What is the treatment for potassium leakage from the kidneys and calcium drop?

[@khaireeystastybites2636]

I want to like this video a million time

[@tanvirrahman869]

Extraordinary! thank you very much.

[@atharvavankhande8906]

In collecting duct, permeability to H+ is low. Therefore, tubular fluid in this part of tubule is more acidic, having PH 4.5...please explain me this sentence

[@romeolhk1008]

God bless you!

[@dikshitkapil4686]

Amazing video but I have a question 1) if in RTA 4 the kidney is unable to excrete H+ then shouldn’t the Ph be towards the alkaline side but the FA states that ph

[@bitterguard5233]

In any acidotic state the appropriate response of kidneys is to excrete H+ which is intact in type 4 rta. In type 1 rta the urine pH is inappropriately >5.5 due to synthesis of NH4+ and PO4 2- as stated in this video. In type 2 rta urine although bicarbonate is excreted but over time it gets depleted so urine pH is < 5.5 and if alkaline therapy is given , Urine pH again becomes >5.5. Hope that's okay.

[@morciego]

This illustration is really good for visual learners, but one thing I still have trouble with is how a normal anion gap is still maintained with the RTAs? All of them seem to be able to affect either the absorption of bicarb or the absorption of Na, which should alter the anion gap when one of them goes wack. If any one can explain it in detail I would greatly appreciate it.

[@olavjonas]

It´s Chloride. Consider chloride and bicarbonate buddies in the anion gap-equation. When bicarbonate gets low, chloride increases, and balances the equation out. In other forms of acidosis, suchs as with lactic acid acidosis, the anion gap is fuckd up because the organic acids which are now in surplus don´t count in on the anion gap-equation (you know, like chloride, bicarbonate, potassium and sodium do)

[@olupotmax9700]

Fantastic, pliz do tutorials for all conditions

[@fereshtahkhoshbakht1999]

Great video 👌

[@sagvankareemtaha1347]

Very understandable explanation

[@عزالدينالشيخسليمان]

Great

[@tacticaltoaster974]

the way he says water

[@arabstaff1]

Cool

[@spirulinachlorella1629]

but why is it called sodium. elemental signs are NA. we say Natrium in germany.

[@tacticaltoaster974]

because french and english chemists preferred to name the element based on where they were found, so Na is in soda and K is in potash

[@issacgeorgy8289]

So you call soda lime as Noda lime 😂

[@ReadySetBret]

Na(2+)?? who allowed this to be published?

[@rainyfairy2200]

Its a simple mistake. What the video has to teach is more than a small mistake. Dont be rude like that

[@Trafie307]

😂

[@MASTERGEEK420]

so in theory you can actually make pee

[@JA3dwards]

God damn the term 'high yield' annoys me so much

[@kimberlibowen3667]

why?

[@user-fq5vb6gj1n]

Gotta be the most dry explanation lol