Immunology Lecture 11 Part 3 Immunologlobulins - structure and synthesis (genetics)

[@ikaties1]

I absolutely love your analogies. I have sat through 6 weeks of lectures in class, with each one, I felt like I was losing brain cells. Yet... I watched your video series over the course of a week, and I can now tell the story behind all the characters, predict their behavior, and actually answer sample test questions correctly. THANK YOU for the videos!

[@mziwonkexola3707]

Simply the best...

[@yeshpatel650]

Let me telling you professor you did a great job! I really appreciate your work, and I will definitely tell my friends to check out your videos. Thank you!

[@DrBeenMedicalLectures]

Thank you for your appreciation. Study well and be a great doctor. Have you checked drbeen.com for more lectures?

[@yeshpatel650]

I just did and I love the way you organized it.

[@DrBeenMedicalLectures]

Excellent. Thank you. Enjoy the study material.

[@anjinaik9371]

U r lecture is amazing I never watch the matured lecture its so good

[@darrylrichmond971]

at 11:54 I believe he meant Hydrophobic (doesn't like to got out in water) Hydrophobic is water hating.

[@alial-dujaili8633]

Extremely helpful, thank you.

[@DrBeenMedicalLectures]

ali al-dujaili you are welcome. Study well!

[@johana9537]

Great video! Beautifully explained, thank you!

[@DrBeenMedicalLectures]

+Johana Moreno you are welcome!

[@surbhisharmasharma5568]

Really it is very useful for understanding the concept

[@saraklobucar]

This was so helpful, thank you! I especially love the candy analogy... that will certainly stick in my brain forever!

[@DrBeenMedicalLectures]

***** you are welcome. Study well - be the best doctor!

[@saraklobucar]

Mobeen Syed Thank you Dr. Mobeen, I'm a meteorologist and not planning to change careers at this point, especially not to a doctor! I am learning about the human immune system for some additional education so thank you for making it so easy.

[@DrBeenMedicalLectures]

***** nice to hear. Reach out to me at [e-mail] if you have specific questions that I can help with.

[@saraklobucar]

Thank you, I just might do that. Now I'm just attempting to grasp immunoglobulin isotypes and their roles, your lectures are certainly helping!

[@zilanayhan7864]

I cannot forget the candy oligosaccharides 😊 Thank you sir, I enjoy the topic thanks to you.

[@leoniesulkie]

This video s really helpful. It makes me understand more about immunology. and because of this such of very interesting and simple lecture style, I'm starting to love Immunology which before this, it was my most unfavourite subject. Now, I'm starting to love it! Thank you very much for this videos.

[@DrBeenMedicalLectures]

+leon mikael good to know. This is the mission. Make medical concepts easy to understand and help students like the subject instead of dreading it.

[@PristineKr]

your an awesome teacher.....thank u sir fr uploading n making immunologlobulins easier fr me easier to understand wish i cud had u has ma teacher....:)

[@alphonseahortensis683]

In ganong from v to hind regions all parts are considered to be fab. Btw suprb lecture sir.u saved me

[@rankawatsourbh8926]

U thought me how to learn things sir thank u your teaching is amazing👌👌

[@ashlyen1]

FC never meant fragment constant ;it is known as fragment crystallizable and name crystallizable is given due to the expermental results produce after reacting with papsin and papain enzymes.

[@DrBeenMedicalLectures]

Cool. Thank you.

[@rankawatsourbh8926]

Fc receptor complement binding site

[@EFTcoach111]

Sir u r very awesome, u made immunology so easy

[@jaydasadia76]

best lecture ever....

[@izzyizzington6321]

thank you so much! such a great explanation!!

[@DrBeenMedicalLectures]

My pleasure.

[@DrBeenMedicalLectures]

Will do. Tomorrow I am recording Immunoglobulin type and functions. Stay tuned!

[@EEinstein100]

Great lecture. Thanks a bunch for its upload. I am a bit confused between 12:00 to 12:30 when you explained about hydrophobic and hydophilic tail and the fact that in one condition the immunoglobulin leaves the cell and in another it get stucked. Can you please paraphrase it for my level of understanding. Thanks in advance for all your help with this

[@Abdifatah-d7y]

thank you alot teacher

[@DrBeenMedicalLectures]

Balvir Singh immunoglobulin types and functions are next lectures. Stay tuned.

[@FiskpisksniskliskNps]

very helpfull ! and I wonder whats going on to his right, he keeps looking there EVERYTIME he turns back from the WB.

[@thribhal]

Hello sir! Kudos to your video! Very well explained. I have just one question. I'm not sure if pepsin is the one that cleave the disulfide bonds between the 2 heavy chains and not papain? Can you correct me regarding this matter sir? Thank you so much in advance. 😊

[@renadmufleh3278]

You helped a lot. Thank you

[@sararefaey2358]

شكرا جزيلاthank you

[@mikey2994]

great video! :) one question though, if papain breaks the hinge region, won't part of the constant region be broken off with the variable region?

[@JuicyCharon]

11:50 Is it Hydrophillic tail or hydrophobic tail? If it's IgM or IgD then they want to stay on the B-cell so it would be hydrophobic tail? Please help me with this.

[@zainabbaqer4713]

please what does it mean "Within the variable region three hypervariable regions determine antigen specificity"? thank you very much for your great lecture.

[@zainabbaqer4713]

yes. thank you very much Sebastiaan Bol

[@BalvirSingh-qn5sz]

Sir please talk about immunoglobulins in more details, anyways its amazing lecture.thankx :)

[@maigomaa1513]

u ’re excellnt

[@supernomiable]

i have question! i am actually confused between hydrophilic and hydrophobic! you mentioned earlier in the lectures that hydrophilic molecules tend to "love water" but here you mentioned hydrophilic hates water so they tend to stay here on the surface cells at constant region via poly A tail! Can you correct me on that? so is the poly A tail hydrophilic or hydrophobic? thank you

[@DrBeenMedicalLectures]

+supernomiable hydrophilic love water. I hope I did not misspeak. Hydrophobic hate water (phobia means fear).

[@manliovalenza7955]

Yes, he wrote hydrophilic on the Poly A tail, but he actually meant hydrophobic.

[@sachinbhokre9102]

Thanks sir.

[@masihmasihmasih]

Hello Doctor. at 4:53 you draw 2x disulfide bonds? is it not only a single one? According to my books there is only one disulfide bridge?

[@DrBeenMedicalLectures]

+Messi Madridista I drew less. Again it is an abstraction :-) Check this link to see that the bonds can be even more than 2: www.ncbi.nlm.nih.gov/pmc/articles/PMC3338938/figure/F2/

[@madamnoor6917]

hy sir ... I wn to knw tht wht includes in bcell activation

[@mehnazali4636]

Heavy chains and light chains are connected by disulphide bond.. Isnt it.?!

[@REBECCANG]

Does anyone knows the difference between B cell receptors and antibody?? It looks the same! So confusing

[@varishakhan3014]

B cell receptors are membrane bound Ig while antibodies are soluble Ig

[@itzamarechevarria8529]

thanks !!!!!!!

[@madamnoor6917]

wht topics it covrs actually....??

[@hasnaasalama5535]

thank U sir U R great ^_____^

[@jagdeepboyat2125]

immunology ke video hindi me bhe banaya kero sir g

[@DrBeenMedicalLectures]

+jagdeep kumar acha ji!

[@PristineKr]

your an awesome teacher.....thank u sir fr uploading n making immunologlobulins easier fr me easier to understand wish i cud had u has ma teacher....:)