Free-water clearance #viveksirsphysiology #vsp

Free-water clearance is the measure of kidney's ability to form concentrated or dilute urine. Kidney separates solutes and water, and then the 'solute-free' water is either conserved into the body or is excreted into urine, depending on the body's need.
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[@VivekSirsPhysiology]

Follow us on social media : Instagram link : instagram.com/vivek.sirs.physiology Facebook link : facebook.com/VivekSirsPhysiology Telegram link : t.me/VivekSirPhysiology Quora link : viveksirsphysiology.quora.com/?invite_code=78ZBTkPc8RBuWmhwtqD7 Website : physiologyguru.com

[@MusicLyrics-gf8oy]

You're the best, no one else made me understand this including my professor....with love from Zambia 💪💪💪

[@106bagishrabha6]

This channels deserves more subscribers

[@VivekSirsPhysiology]

Thanks for the good wishes and faith….! Regards,

[@parameswarpanda3793]

Amazing explaination sir. Everthing is crytal clear🙏🏻🙏🏻

[@VivekSirsPhysiology]

Thanks for the comment…!

[@gregattac5458]

Your work is much appreciated, i don't think there is a physiology learning resource on youtube, which is explaining concepts more clearly and accurately.

[@VivekSirsPhysiology]

Thanks...! Such reviews and comments motivate me to continue the work with passion.

[@106bagishrabha6]

Thank you sir

[@mohitsharmma113]

Thankyou sir , beautifully explained

[@narasimha7870]

The best explanation of free water clearance sir .....U r great

[@VivekSirsPhysiology]

Thanks! I feel humbled when i get such great reviews.

[@devangeesoni4753]

Very good presentation. Sir where can I find the next videos of yours related to clearance

[@VivekSirsPhysiology]

Thanks. Prepladder videos have the discussion on clearance, including the concept of clearance, inulin & PAH clearance, and other aspects.

[@devangeesoni4753]

Sir where can I find discussion related to clearance

[@faisalramzandar624]

Respected Sir . I'm Your Big fan sir but I have a doubt . I got no response from prepladder . Sir What's The Difference between gfr and clearance . I'm getting everytime confused in it . We use the same formula to calculate both .

[@VivekSirsPhysiology]

Clearance = (U x V)/P. The numerator is (U x V). It is the total excretion rate of a substance, into urine, per unit time. A substance is excreted into the urine by TWO processes ~ (1) glomerular filtration [So GFR included] , and (2) tubular secretion. That’s one difference between clearance and GFR. Clearance will include both processes - GFR and tubular secretion. Another point:- GFR tells us about the filtration rate of a substance per unit time. Clearance is the RATIO (Ux V) /P. Clearance tells us, how much was the concentration of that substance in the plasma (that is, denominator P), and from that, how much is being excreted into the urine per unit time (that is numerator U x V).

[@faisalramzandar624]

@@VivekSirsPhysiology Sir it means That we measure gfr via Clearance Only for those substances whose clearance and Gfr are almost same . OTHERWISE these are two different terms .

[@VivekSirsPhysiology]

We don't measure GFR from clearance. GFR has another formula (net filtration pressure X capillary filtration coefficient) which i have described in videos (prepladder). And, clearance is equal to GFR for some substances like inulin. But still, GFR is the absolute filtration rate of a substance, whereas clearance is the RATIO (means, in clearance, we also consider its plasma concentration, which we don't take in GFR).

[@faisalramzandar624]

@@VivekSirsPhysiology Thank You very much Sir . Got It sir.. nobody explained it to me like you sir . God bless You.

[@hiteshvishwakarma6449]

Thank u sir