Warfarin | Mechanism of Action, Indications, Adverse Reactions, Contraindications

[@brianwilkerson2513]

I’m working on my FNP and these videos are invaluable. You’re a great teacher and your style really helps the info stick. I would REALLY appreciate more Pharm videos like this.

[@hughsandys]

Dude, thank you so much. I am taking pharmacology online and there are literally no lectures to explain anything. These videos are priceless. For sure donating.

[@muskandeshwal9299]

The most underrated channel

[@eimaanish]

He saved my thesis presentation

[@benjaminanokye3070]

Serious💥💥💥💥💯💯. The best

[@alisufyan4774]

20:05 Excellent video I was specifically looking for memorizing warfarin interactions

[@daviddivineful]

I work on a cardiovascular IMU. We use heparin for the inpatient. Xarelto or Eliquis are prescribed for the patient being discharged. Also, the inpatient is started on Xarelto or Eliquis before being discharged. Basically, the patient is being "bridged" before he/she leaves. Warfarin is less commonly prescribed. Regardless, this video is awesome and very helpful. I have already watched the "Heparin" video. Another awesome video from the plethora of videos by Ninja Nerd.

[@shivubains115]

This is the one of the best lecture I have ever attended doing a great work sir 😊

[@annaflores4322]

As a last semester medical student, you lectures have been saving my pharmacology as I struggle to understand! Thank you so much for these. I will continue to promote your work to everyone. Appreciate you and the time it takes! Please continue to build up the medications videos! Love from Puerto Rico.

[@AhmadKhebbaiz]

please do a video about the acid-base balance!!!!! please :) YOURE THE BEST

[@yarashhab]

i agreeeee

[@drconkle1]

Yeeeesssssss please!!!!!

[@ahmadsadain203]

Agreee

[@HandleHandle233]

👏👏👏👏

[@sunnyglo9135]

yess

[@Hadeel_Alhamad]

I wish this video was available one and half year back it would have saved me from alot of confusion, i am not complaining now, still feel so grateful of having it 💝🌹

[@jessica3609]

Favorite KZbin channel forever

[@UlyashaStudy]

Your channel is the best,thanks

[@anaclairebanlasan2514]

Wow! New vids for 2020! Thrilled to have you back! 🙏❤🧐

[@t1g3r2009]

As a Medical Laboratory Science Professional that runs this PT INR test: INR is calculated by taking the patient's PT/average normal PT, raising it to the power of the ISI = (Patient PT/Avg PT)^ISI. PT does not equal INR. Normal PT is typically around 12seconds. Just a small correction that wanted you to be aware. Great videos though. I teach Hematology Labs for a Medical Lab Science program and your videos are super helpful!

[@gazzarose6296]

Fantastic teaching

[@JunctionFeatherWorks]

Thank you!! This made everything crystal clear!! More bloopers please….I laughed SO HARD at the end 😂

[@vishalmotwani7664]

God blessed me the day I found your channel💎

[@vanw1504]

This was the best Wafarin video I’ve seen! Thank you!

[@rozi7695]

It’s my last year at high school and I’m about to start on my last project which I have decided to write about Warfarin And you literally covered every thing I had to know for a big part of my project. Your way of teaching is so greattt😍❤️ I’ve though a little suggestion. You can maybe upload the links you mention that we can go back to if we get confused about some concept you are using. Thank you so much😍

[@athinaios-1959]

So, if Thrombin is active and helps creating fibrin only when factor Xa is present, how is it that Thrombin is bound to thrombomodulin, helping to keep the blood normally thin? You are great , thank you for your work!

[@atpunkn9788]

Good question

[@aathifa20]

I AM SO GLAD! TWO VIDEOS IN A DAY ❤️

[@ayamej1093]

Love u guys, God bless you all ❤️

[@ssssal413]

Amazing honestly

[@keerthana8677]

This is the best lecture I've ever had,🥰🥰🥰

[@mohadisaathar5368]

Many many many thanks buddy! All videos are amazing and useful.. You are the only one❤ God bless you and hope to have success and happiness in your life!

[@anonym-gz6ro]

YOU ARE A LIFE SAVER!!!!!! thanks to you im still in med school ahah. Keep going!

[@mohammedbarakati2486]

My favourite tutor 🌹thanks Zach

[@ashifkhan4694]

Plzz Make a video on "Wound Healing"

[@nilster09]

wow i wish i would have known about this video before my exam! this is by far more easy to understand than the high yield med review videos! i love how you explain everything and your little images you draw that make it more fun to watch :)

[@nasirteha377]

wow!! please do a video on full physical examination with it's related findings. we want that

[@shahiramohammadi7284]

Great teacher ever

[@3APNHA]

MEDICATIONS FROM NINJA NERDDDDDD!!!!! YESSSSS IM SO EXCITED

[@muhammadsardar37333]

Thank youu very much ♥️i hope you make a video about fibrinolytic drug also👍🏻

[@Medico.studi12]

You made every day one video plz sir in pharmacology

[@ElFuckingBlackKing]

You're the best! Keep up the real work.

[@architasaha8917]

Super super . Your concept is really great. Impressive job.

[@abdelhafiz236]

Liking the video before watching it 💯 thank you

[@ryanweber2378]

I am not an engineer, but I love these videos. I have learned much. I am a Type 1 diabetic. It has killed my kidneys. I know you covered much on the glucose side of things. But I was wanting to know if you could make videos in the future on the extreme damage Diabetes can do on the human body and the organs. Thanks!!!

[@egeugur8107]

ryan weber he says "ninja nerds" not "engineers" 😄

[@bhargavpatel4262]

Hi!! Sir, can you please possibly make video on digoxin? Great videos!! Ninja nerds forever ✌

[@stefanazdravkovic2914]

I love u, u save my life with your lessons and i love medicine bcs of u! (sorry for my bad english grammar) 😅

[@hesikaprabashwara9421]

That would be great if you can explain of streptokinase🥺

[@juliarampelsberger7889]

You are the best!

[@MrBababuwi]

Amiodarone could also affect Warfarin metablisim and increase INR. You should mention that on your video as it is commonly used drug for AFib although it is only in in-patient setting.

[@daviddivineful]

Great observation. Thanks for mentioning that.

[@ethancowart6765]

Damn crazy detail I don’t know how you can know all this stuff lol kinda crazy man

[@Be1smaht]

You make me want to learn about this stuff..

[@sapnakarunathilaka6447]

Thank you very much sir ♥️🙏

[@samyhaddadou161]

I have never enjoyed a youtube video so much.

[@medicoanu7210]

Thankyou so much Sir

[@tydyislover]

Thank you so muchhhh 🙏🏻🙏🏻 from Thailand

[@ooasessinoo]

muy bueno muchas gracias por el video.

[@Dr.Nadiyah.AbdUlhamed]

amazing ❤❤❤

[@muffinshw2984]

What a concept ! Thank you

[@landisjohnson627]

Thanks for making these videos.

[@AM-wg1yk]

thanks

[@maryamsafarian5677]

Thank you 😊

[@sivajinidarmendra2250]

Thanks Bro

[@phongdao3831]

thank you very much ,

[@kirilova98]

Thank you so much

[@supazta2]

replayed bloopers x5 haha, nice way to end the lecture

[@markarca6360]

What do anticoagulants and rat poison have in common? Coumarins. And an O.D. of coumadin and poisoning involving coumatetralyl compounds has 1 antidote: phytomenadione (Vit. K)

[@thephoenix85]

Awesome Zack thnks bro

[@ayajamal5639]

You are amazing thank you 👏🏻

[@Borlingr]

love your videos man!

[@burhanuddinmohammadi8566]

The last part has been so funny🤣😂

[@danielborok5611]

Hi Zach! In your opinion, how risky are Intra Muscular injections during warfarin treatment with an INR of 2.4? How likely am I to develop a haematoma? I have pernicious anemia, which is treated with a monthly dose of 1000ug cobalamid (vitamin B12), intra muscular. Thanks, Bro!

[@PepsiT98]

you fascinate me!!

[@lillianotuokwu5800]

great❤

[@bilqishkaridza7413]

Thank youuuu you help us alot💕💕💕💕

[@halaalabboud480]

ninja nerd rocks as usual ^~^

[@Jackiesguineapigs]

any info on Sinthrome or Acumarol anticoagulants

[@dr.k3598]

Why we are giving vitamin k for increase INR , how its gonna work , you previously said it increases bleeding

[@Liliana_Lili_]

Can you do a video on volatile anaesthetic agents and anaesthetic gases ?

[@haneen8083]

Thank you 💜💜

[@mohammedsublaban8518]

How long after quitting warfarin I can check the protein C

[@muskandeshwal9299]

That blooper at the end though 😂😂😂😂

[@sabik-6808]

Sir plz upload a lecture about opoid pharmacology plz..

[@asmaalhussami9024]

thank u so much

[@choozomano977]

Thanks a lot ❤

[@medicallifewithjohn]

awesome

[@abdisamadahmedyasinshcali8927]

Legend Zach murrphy

[@ed9519]

so is what u said on this vid true for other AVK such as acenocoumarol ? or is it just warfarin

[@deepakbihani3344]

u r great sir

[@PS-sf8tw]

Vv good zach

[@Zetsuke4]

YES

[@rubyjeanvirlymadani8375]

Hi , may you help us to create an explanation video about chest tube please ?The concept and the management of it ..thank you

[@hugo3conde]

For someone who is about to start taking warfarin - this is invaluable information. For someone who is super anxious - this is wayyyyy too much information :(

[@BG-ez6bz]

Am second to like 😝😂 thank you very much guys for helping us. 🤝🤝🤝🤝

[@3APNHA]

I HAVENET EVEN WATCHED THE VIDEO YET - JUST WAITING FOR THE SHEN YUN BALLET AD TO FINISH

[@lakshman-sridhar9165]

Oh man... U r now motivator

[@raulcapelo]

melhor professorrrrr

[@Di_Moriarti]

a stylish cap!

[@shahiramohammadi7284]

👏🏻👏🏻

[@rachelkhoury6943]

More pharmacology videos

[@reemeldib5377]

Best

[@Demothones]

I just noticed that you have ETOH on both sides of the CYP450. Great video, though.

[@likesomethingsomething8927]

and both are correct: a) if you drink a lot one day - EtOH molecules compete with other molecules for spot in available cytochromes. warfarin can't be metabolised enough, so there is more warfarin in blood. b) if you drink for a long time - your organism feels that he need more cytochromes, because you give him substrates like every day. so in response - you have more cytochromes to metabolise molecules like warfarin, what leads to reduced concentration of warfarin in blood.

[@zheersarhad248]

👍👍

[@salmanarcia8922]

👏🏽👏🏽👏🏽👏🏽

[@Goodbadie]

احبك

[@pervinkrimova7062]

👍

[@h4zeemm728]

I am in love

[@manchesteryoutube2108]

Ive stopped taking my warfarin. I don't want to get better