Webinar: Resolving flexibility and heterogeneity with 3D Variability Analysis

  Рет қаралды 7,504

Structura Biotechnology Inc.

Structura Biotechnology Inc.

Күн бұрын

Learn how the new 3D Variability Analysis (3DVA) algorithm in cryoSPARC can reveal new functional and biological insight into the conformational and flexible motion dynamics of a protein molecule from single particle cryo-EM data.
We will cover the new concepts introduced by the algorithm, interpretation of results, several case studies and examples, practical considerations to keep in mind when working on your own data, and live audience Q&A. 3DVA has already been used in many notable structural studies to shed light on protein dynamics, including GPCR structures and the SARS-CoV-2 spike protein. To read ahead, see the 3DVA preprint at www.biorxiv.or...
To learn more about cryoSPARC, please visit: cryosparc.com/
00:00 Introduction
57:44 Q&A

Пікірлер
CryoSPARC 3D Flexible Refinement Tutorial
1:22:11
Structura Biotechnology Inc.
Рет қаралды 12 М.
Troubleshooting in cryo-EM Sample Preparation
31:31
Center for Electron Microscopy and Analysis
Рет қаралды 5 М.
Brawl Stars Edit😈📕
00:15
Kan Andrey
Рет қаралды 26 МЛН
Fake watermelon by Secret Vlog
00:16
Secret Vlog
Рет қаралды 15 МЛН
Basics of single-particle cryo-EM image processing
1:00:03
Pavel Afanasyev
Рет қаралды 8 М.
Cryo-EM17 lecture 06: Image refinement in 2D and 3D - Sjors Scheres
53:46
MRC Laboratory of Molecular Biology
Рет қаралды 10 М.
Optimising sample preparation for CryoEM
55:30
Instruct-ERIC
Рет қаралды 4 М.
Why Democracy Is Mathematically Impossible
23:34
Veritasium
Рет қаралды 3,9 МЛН
Introduction to Single Particle Data Analysis Using cryoSPARC
1:01:12
Center for Electron Microscopy and Analysis
Рет қаралды 10 М.
Processing difficult datasets in cryo-EM - Kelly Nguyen
44:43
MRC Laboratory of Molecular Biology
Рет қаралды 2,8 М.
CryoSPARC 3D Flexible Refinement Mesh Preparation Tutorial
28:08
Structura Biotechnology Inc.
Рет қаралды 3,7 М.
Ellen Zhoung - Machine learning for determining protein structure and dynamics from cryo-EM images
48:30
Institute for Pure & Applied Mathematics (IPAM)
Рет қаралды 2,4 М.
Localized Refinement in cryoSPARC (NSP15 Case Study)
9:28
Cryo EM Tutorials
Рет қаралды 7 М.
RELION
51:48
SBGrid Consortium
Рет қаралды 10 М.