Williamson Ether Synthesis

[@ProfessorDaveExplains]

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An update in case you still read comments on your old videos. I just graduated with my Chem B.S in December, and have an amazing industry job now. Thanks for the help, Dave.

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What job is that? And how’d you find it?

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@@NewWesternFront Really flexible CRO where I was able to learn a lot about the theory and instrumentation of LC-MS. Since moved on to big pharma. I just applied directly through their website, job boards are great tho.

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Please do more Organic Chem 2 reactions. Your videos are so much more clear than our lectures. Seems like you're speaking English, and my professor is speaking Chinese.

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that moment when youre from germany but use english tutorials out of pure desperation

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You made me understand this and I never thought I'd understand Organic Chemistry!!! TYSM

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Perfect explanation, as usual. I'm watching all your orgo 1 videos before my final. Thank you♥️

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[@NewWesternFront]

P Dave has high expectations of us. I love it

[@merveyldrm6923]

Oh best explanation in youtube, you made my day. The way that you explain, you are giving background information on why the reaction occurred like that, it makes clear everything! Thank you very much!

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Been watching Professor Dave since Honors chemistry my sophomore year of high school, all the way through AP chem, AP bio, Chem I and II in college, and now in Organic Chem I. Hands down the best chemistry channel! I want to teach high school chem and bio after I graduate and I'll definitely be recommending these to my students!

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Why did you take chem I in college if you took AP Chem

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Dave...every time we learn a new reaction I swear you make a video about it the next day! Do you have my course schedule??

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I've been lurking in the back of the room!

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Very useful for students throughout the globe. For me it’s the conceptual clarity within 10 mins. Appreciation! 🙏🏻

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I was searching for this for long, This Helped, Thankyou so much!!

[@kellyfrances9435]

No way. It can't be this simple :O I thought this synthesis was very hard to understand until I watched your video.

[@revisionarcformyalevels]

Hello sir, amazing video! Please could you explain why in the third question you wouldn't get hydrolysis on the chloride?

[@shivanshumaurya_]

I think if there's intermolecular shifting possible there's no need of hydrolysis. Moreover it can increase the chances of elimination

[@ronakjain1872]

one important thing that R-X must be 1 degree or elimination competes over substituion and alkene are formed

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Dude you are awesome. This helped me understand so much better, thank you prof. Dave!!

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i love your intro, makes me happy.

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Hey man, thank you a lot! You made me understand this - although you speak English - an my professor teaches in German. Now it seems so obvious.

[@MuhyiHaruna]

Thank you so much sir, but do you mean that if the reagent is not an alkyl the product is going to be cyclic compound?

[@thechannelofeandmx4784]

You uploaded just in time 😆We just started studying about ethers so this will help a lot!

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You explain well on all video's am a big fan 😎

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i love your channel

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Love your videos, thanks!

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Thank you professor Dave

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Thank you for the video! Really helpful!

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I am a simple student who cheated his way out of grade 11 and grade 12. You're helping me in my university exams now lol

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Love from India sir😊

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Thank you Jesus!! for helping me pass my Chemistry test 😭😭

[@ibrhmmcht3907]

is it possible that ,in the example 3, being a huge cyclic whit one more alcocide?

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So helpful! Thank you!

[@malamri424]

is it 1 pot or should you first do the alkoxi?

[@paulgrainger9771]

Thanks Dave

[@leylaz.6205]

Thank you for you video! I have a question on the 3. Example. I paused the video to solve it by myself. And i wanted to ask you, if it is possible to get an NaCl as a sideproduct instead of Cl- just leaving?

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Thanks sir.... From Kerala.india

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Ur the best dave

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Thanks a lot sir... That helped me a lot..

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Do you give any courses or only youtube?

[@ihorfesina1622]

Do we have here E2 side reaction?

[@kathrindn2195]

What exactly is the role of the water in the third example reaction? It's not really participating in the reaction, is it? So wouldn't the same reaction also take place in a non-aqueous system?

[@NewWesternFront]

This is a great question that I think Leah4Sci helped to answer for me. I think the idea is that if your solvent is the conjugate acid of the Nphile/Base, then it doesn’t solvate said molecule too much. But it can still stabilize carbocations and whatnot. Weigh in Davedawg?

[@leylaz.6205]

h2o is the product of OH- attacking the alkoholic group.

[@kelseybrennan3127]

thank you

[@joeferdin9871]

In the 3rd problem,will the -OH displace-Cl by sn2 since it's a strong base and primary alkyl halide?

[@ProfessorDaveExplains]

Very strong base, will do acid-base reaction much faster than coordinating.

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Thank you so much sir

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Thanks dave

[@fanimeproductionst.v.3735]

Why doesn't the Na+ ion react to the O- part of the hydrocarbon in the beginning???

[@ProfessorDaveExplains]

It'll hang out by the oxyanion until it reacts.

[@ngozinwachukwu158]

fantastic

[@nabilaa9749]

Is possible to make ether from alkyl halide?

[@ProfessorDaveExplains]

that's what would be explained in this video you're commenting on.

[@godhelpme8977]

Sn2 mechanism

[@michellegutierrez2119]

Ether =💨 + β ond = more tangible compounds .

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cheers

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Hi

[@thelukesternater]

So if I drink it I’ll smell like it? So just huff you say?

[@thelukesternater]

Wrong ether? Dam I’m over here trying to meme and I’m learning like a nerd

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check out "ask professor dave #3", i talk all about it!

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Ehre Bro

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Good morning form Queensland Australia 30AUG2018

[@IsaacTreadway]

You ether get it or you don't I guess.

[@Husain_bohra]

I think it's not hard to not able to guess it By - Williamson

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thanks my boy