Will I Survive Breast Cancer? Effects of Stage and Biology on Prognosis

[@cheriea1670]

Excellent explanations, thank you so much. Stage 3 IDC here, undergoing treatments. May GOD bless and keep all of us as we trust Him and strive to lead a longer life ❤ Love all your videos, best channel on KZbin!

[@yerbba]

Thank you for your kind words and blessings. We’re glad to hear that you find our explanations helpful. Wishing you all the best with your treatments and our Yerbba community is here to support you!

[@lucianac4388]

Good luck for everybody with breast cancer watching this excelente vídeo ❤

[@AuGAlaN]

Commenting because you are amazing! I'm so glad I found this channel, thank you Dr Yerbba

[@yerbba]

Thank you for the positive feedback! We're glad you found Yerbba too!

[@lanacampbell-moore6686]

I was diagnosed in May & start chemo on Monday & Thank you 🤍

[@yerbba]

Thank you for watching and we wish you the best

[@iamwinningrightnow]

You got this!

[@mammabear2183]

This was extremely helpful, but what about HER2 ?? And what about inflammatory? Can you please do another video like this for those 2?

[@yerbba]

Stay tuned for our upcoming video about survival statistics. With HER2-directed therapy, the prognosis with HER2-positive breast cancer is similar to HER2-negative breast cancer.

[@elsyromero5580]

Is this already available? ​@@yerbba

[@naththomas9946]

Thank you for your helpful and educational advice.

[@yerbba]

You're welcome, thank you for watching.

[@christinevaseer9122]

Is grade of cancer not relevant in this discussion? Wouldn’t the expected survival rate vary with this too?

[@yerbba]

Yes, grade is important and is one of the characteristics people look at when talking about the tumor's "personality" along with estrogen and progesterone receptors and HER2 status. You may want to check out our video on tumor grade here: kzbin.info/www/bejne/oYbSeJ-QprCKatE.

[@nonyabiness4023]

Thank you for explaining this. I have triple negative breast cancer. I just had a bilateral mastectomy 2 weeks ago. Lymph nodes were all negative for malignancy. Breast tissue was negative for malignancy. The tumor was only 7x4mm in size. It was found during annual mammogram because I had a different type of carcinoma 12 years ago. I have children to live for. With triple negative that small, after bilateral mastectomy and my oncologist still said chemo starts soon, what is your opinion? He seems to think I have a good prognosis. But triple negative is scary.

[@yerbba]

It sounds like it's clearer to you that your prognosis is good. Chemotherapy can make it even better. I know it's a lot to go through, and you have to make sure that you're comfortable with the decision. The size cut off we use is 6 mm, so you're just over that. All the best.

[@nonyabiness4023]

@@yerbba Thank you. You confirmed what my oncologist said. Peace of mind! Take care! 💞🌸

[@webster60cl42]

My daughter has stage 4 larger tumor and 1 lymph node( surrounding lymph nodes were negative. Dbl mastectomy. What is the chart for her survival rate.

[@yerbba]

The prognosis and life expectancy in people with Stage IV (4) breast cancer depends on how much overall cancer there is throughout the body (in the liver, lung, bones), whether or not the tumor has the estrogen and/or progesterone receptors, and how able the person is to care for themselves. It's not clear from your question that your daughter has cancer in other parts of the body. If not, it is likely that she does not have Stage IV disease. This may be something to clarify with her medical team. Please write back if you have other comments, and thank you for sharing your daughter's experience.

[@prashantkale3061]

Locally advanced breast cancer..Tumor size 5 cm axilla 3 nodes possivite..first treat neoadjuant chemo..then MRM done..and currently adjuvent chemo ( cytax ..paclitaxel) 2 cycle done totally 4 cycle prescribed...mam treatment ate right way...PR Er possitive her2 negative ( biopsy report)

[@yerbba]

It sounds like you’re going through an intense and well-structured treatment plan for your locally advanced breast cancer. Starting with neoadjuvant chemo, then surgery, and now adjuvant chemo is a strong approach. Keep pushing through those chemo cycles-you’re doing great.

[@prashantkale3061]

​@@yerbbaThank you...

[@Noor_r]

Hi my mother was diagnosed with stage 2 grade 3 invasive ductal carcinoma (tumor-4.5 cm) with ER PR negative and HER2 positive and has undergone a single mastectomy with all lymph nodes(17 of them) negative. As of now she is going undergoing treatment where she’s done with her 6 chemo sessions and taking her targeted therapy. I wanted to check your opinion on the prognosis for this situation.

[@yerbba]

Thanks for watching and your question. It sounds as if your mother has received the right treatment. In general, people whose tumors are HER2-positive will complete a full year of trastuzumab unless there are heart problems. With the negative lymph nodes and the treatment you describe, the chances are better than not that the disease will not recur. Remember that we can provide only statistics. That is, the data about survival are for groups of people rather than for an individual. It is so hard to live with that uncertainty. Wishing you and your mother the best.

[@Noor_r]

@@yerbba thankyou so much

[@aspirant7395]

Ma’am my mother age 56 has been diagnosed with IDC T3N2M0 her2+ Er-,Pr-, ki67- 30% . she has completed 8cycles of chemotherapy (4(ADR+cyclo) + 4(pacli + trastuzumab) ) Followed by MRM and is currently undergoing RT of 15 fractions. What is the prognosis and also i want to know about the reoccurance in future. Eagarly waiting for your reply . Thnk you

[@yerbba]

Your mother is fortunate to have you. In people who receive chemotherapy before surgery, it's helpful to see how well the chemotherapy worked. You can ask her medical team (oncologists are the best at answering this question) how much cell death was seen in the surgical specimen. If there was a lot of cell death, her prognosis is better than if there was minimal response to treatment. We wish we could give more specific information about prognosis, but without seeing the surgical specimen and having all the information, it is hard for us to do that.

[@christinevaseer9122]

This was helpful, but depressing. Could put someone in quite a state of despair

[@yerbba]

For some people, despair is their reaction. It may be helpful to watch the stories you're telling yourself. That is, are you telling yourself that the cancer will "probably come back"? Or rather, "I've done everything I can, and that's the best I can do"? Even in people with Stage III disease, the cancer is more likely not to come back than it is. We've also found that worrying about it does not keep it from coming back. Wishing you the best as you continue to heal.

[@sashagirl1987]

I was diagnosed with stage 2 ductal breast cancer on July 23,2020. I had a double mastectomy on sept 2, 2020. I’m still confused on all the terms and meanings but my oncologist said my cancer was Her2 negative. My tumor was 6 centimeters in size. My oncologist said I didn’t need chemo which I was grateful for because that was a huge fear of mine. But now, 2 years later I wonder if my dr made the right decision for no chemo? I live with fear daily of did we do enough to make sure cancer doesn’t show up somewhere else in my body. They did take 2-4 lymph nodes during the mastectomy and said one had tiny trace amounts of cancer cells. I still don’t understand what all this means. I am on Letrozole 2.5 mg for five years. I live in fear daily of it coming back somewhere else in my body. Do you have any advice as to whether I did the right steps?

[@yerbba]

Thanks for writing. The fact that you are two years out from your diagnosis and are doing well is helpful. While it is tempting to wonder, "Should I…?" there is certainly no evidence that the wrong decision was made. Many people do not need chemotherapy. And even in people who do, chemotherapy does not offer any guarantees. We are hoping you might be able to put this behind you. You made the best decision you could with the guidance of your medical team. Wishing you well.

[@missminnie1493]

You have to live your life with no worries that's what you do!

[@maliniramadass9220]

Hi mam, my mom stage 4 breast cancer (er+, pr-ve , her neu +ve) . After 4 cycle pet shows partial response. Started 5th one along with harmonal. Doc has suggested breast surgery after 8th cycle . Please advise

[@yerbba]

A partial response is really encouraging. While surgery of the breast will not improve survival, many people want to treat the breast surgically for cosmetic reasons or psychological reasons. Many people wait until they've recovered from chemotherapy and their doctors are confident that the disease is under control. It can take a full year for the full effects of hormonal therapy to work, so waiting is a reasonable option.

[@G-rq7dz]

What is the 10 year prognosis for Stage 2 synchronous bilateral invasive ductal carcinoma, no nodes but skin infiltration? Grade 2 right, grade 3 left, ER+,PR+, premenopause.Thanks

[@yerbba]

Thanks for the question. The majority of people with the type of cancer you describe will be alive at 10 years without disease. It might be worth asking your medical team to go through the staging with you because of the skin involvement. Wishing you the best.

[@Chirag-i1j]

Hi, what if a patient has a low grade IDC and the tumor is already removed (Size less than 2 CM), and the lympnodes, margin, skin everything has come free of tumor in the histopathological report, but its showing perineural Invasion as present and I am little bit worried about this and there's very limited information about the perineural invasion, please provide any information about Perineural Invasion and can we overcome it with the help of chemotherapy and radiotherapy, thanks

[@yerbba]

Great question. Perineurial invasion does not appear to be an independent prognostic factor. The other tumor features under the microscope, such as tumor grade and hormone receptor and HER2 status, on the other hand, are important prognostic factors.

[@Chirag-i1j]

@@yerbba Thank You for the reply, after biopsy and ImmonoHistochemistry test, below are the findings. Tumor Size: 2.5 Lympnodes: 0 ER+/PR+ of overall score 7 Her-2 Neu is -ve of score 0 Ki-67 is 15%, considering these factors how important is a perineural invasion for a prognosis. Please provide any information available. Thanks

[@salomemk4543]

How is the method of treatment decision made when it comes to surgery first vs chemotherapy. My mom was diagnosed with poorly defined invasive ductal carcinoma, tumor measuring up to 9cm at this point. Treatment plan however is 6 sessions of TCHP once in every 3 weeks before anything else. I'm worried having that size of a tumor and a chemo first isn't the most optimal approach. What would you say? Thank you!

[@yerbba]

Good question. If someone is going to receive systemic therapy with chemotherapy (with or without targeted therapy), given that treatment before surgery is a wonderful option. For a tumor like the one you're describing, primary systemic therapy is fairly standard.

[@coolgirlsuchi]

Hello Doctor do you consider PCR also during this statistics? I have TNBC completed my treatment. I had 8 rounds of chemo with carboplatin and lumpectomy and radiation 18 rounds. Achieved PCR what will be my prognosis

[@yerbba]

A pathological response means that no tumor was found after the completion of primary (neoadjuvant) chemotherapy (with or without targeted therapy). A pathological complete response is a favorable prognostic factor.

[@Angie-og1jg]

Are those survival rates with or without treatment?

[@yerbba]

Most of the survival rates we give are with treatment.

[@briggettecammett6181]

Will aromatase inhibitors help if u start them 11 months after a stage 1, node negative, clear margins lumpectomy? I worry about the cardiac side effects of Arimedex. Thank you.

[@yerbba]

Great question. Yes, you would benefit from starting even 11 months later. The cardiac effects are low for a given person. We had to study thousands of patients even to discover that cardiac problems were more common than in those on tamoxifen. You can be followed for your cholesterol and other cardiac risk factors.

[@briggettecammett6181]

@@yerbba Thank u for your response.

[@seharnajam2887]

I was diagnosed with breast DCIS last one year ago..2cm lump during 6th month of pregnancy...had 8 chemotherapy,surgery and 27 sessions of radiations...now i'm on tamoxifen and trastuzumab(4 doses taken)...what about chances of recurring and prognosis in my case??i'm having triple positive.

[@yerbba]

Thanks for writing. It is hard to estimate your odds of recurrence-free survival without being part of your medical team. In general, however, DCIS is not treated with chemotherapy. It would be worth getting more information about your diagnosis.

[@hasibahmed4050]

My Mom is suffering from breast cancer. Her pathological report is ER, PR is positive and Her-2 negative, Stage 1, Grade 2, and Tumour size 1.5 cm. Lumpectomy and Radiotherapy with Auxila are done. No SLNB and Auxila dissection is done. Now hormone therapy ( Exemastine) is continued. Are we on the right track? Can we skip hormone therapy after taking 4 months because of side effects?

[@yerbba]

The hormonal therapy is an important part of your mother's treatment plan. If the first medication is causing unmanageable side effects, trying one of the other aromatase inhibitors and, if that is no better, trying tamoxifen would all be reasonable options.

[@vaishnavimankar200]

Same here... what's the age of your mother

[@vaishnavimankar200]

And did your mother use chemotherapy

[@manishaingle-hf1ol]

Invasive triple positive breast cancer her 2 positive grade 2 (they didn't tell about stage but it hasn't spread from.breast) dr recommend chemo before surgery then breast remove. What do you think mam?

[@yerbba]

Having chemotherapy before surgery offers some benefits, including getting started soon. You may find our video on neoadjuvant treatment to be helpful: kzbin.info/www/bejne/jJrRo3V-p8efj5o

[@user-cy5ls9ge8w]

Dcis birads 5 survival rate after mastectomy and hormonal treatment and no chemotherapy or radiation therapy

[@yerbba]

For DCIS (non-invasive breast cancer, Stage 0), the survival rate is nearly 100%. Rarely, DCIS after mastectomy can reappear, but this is extremely uncommon.

[@ashanagini8596]

My mother detected with breast cancer 2 years ago.and she choose ayurvedic treatment.now tumour size increased and ruptured.now can we go to allopathy..is there any treatment in such cases. Ur reply means a lot.thanku

[@yerbba]

Your mother is fortunate to have you looking out for her. It is very likely that allopathic medicine will indeed be able to help her if she is willing to go that route. Keep coming back here and let us know what you need.

[@sajidmajeed8790]

Hi my mother was diagnosed with ist stage cancer when lumphectomy done after that doctors decided to clear axilla when we sent the axilla nodes for test the report was 8 of nodes positive Now doctors told that it's 3rd stage We did pet ct scan before axilla surgery The report was normal no cancer detected even no molecular active cell there. Er pr positive her2 negative by FISH test Now doctors are going for chemo and radio Just tell me what is happening

[@yerbba]

The only way to know for sure about the lymph node status is to examine the nodes under a microscope as you've discovered. We try not to tell people what their stage is before we know the lymph node status because of this exact scenario. Wishing you and your mother the best.

[@rebeccastora8398]

I have IIIC/4 triple negative cancer. I received 2 types of Chemo, a double mastectomy, and 32 rounds of radiation that had to be altered due to lympho vascular invasion. I am now receiving Keytruda & Xeloda. I cannot get my doctors to give me a straight answer, and insurance just deemed a PET scan not medically necessary. I am so confused. Why would I be left so in the dark??

[@yerbba]

Thanks for writing. This is a great question. The treatment you've had and the treatment you are on are designed to treat any tiny and invisible cells that are left in your body. There is no evidence that having PET scans or other scans after breast cancer will improve your outcomes. If you were to have symptoms, then scans would be appropriate. We basically assume that there are cancer cells elsewhere in your body and treat them with all the medicines you are on. It is so hard to live with uncertainty, but a negative scan does not mean that there is no cancer. Treating someone like you as fully as they are is excellent care.

[@rebeccastora8398]

@@yerbba Thank you so much for taking the time to reply. That does make a tremendous amount of sense.

[@Alexanderthegreatjones]

Are you still going through this?

[@harveygalang9342]

My wife got lumpectomy right breast she is on chemo right now sunddenly she feel a lump in left breast while on chemo ! I’m worried but she got mri before the left breast is negative only benign cyst ?

[@yerbba]

It's important to make sure that you and your wife feel comfortable with the test results. I suggest you bring this up with your wife's medical team the very next time you see them.

[@sadruddinshafiq9305]

Hi my wife was diagnosed with grade 2 and 3 DCIS with ER -ve. What’s the best option where the recurrence is minimal. Would she be given radiation and chemo as well? What’s your suggestion as we have an appointment with surgeon next week. And do you think which option is best Mastectomy or lumpectomy?? Thank you.

[@yerbba]

Thanks for watching. If your wife has only ductal carcinoma in situ (DCIS) with no invasive component, chemotherapy is not part of the treatment plan. Without knowing more details about your wife's case, it's hard for us to provide more information. Please check out our other videos.

[@sudeshnachowdhury1488]

What about stage 2a...pr(11 20%)er negative ..her2neu-negative

[@yerbba]

Thanks for writing. Although the tumor biology features of this cancer are relatively "unfavorable," the stage is still quite early. The goal of treatment will be to cure this cancer, and chemotherapy can be highly effective in reducing the risk of cancer recurring. Wishing you all the best.

[@joyceweber4299]

MY BREAST CANCERCAME BACK THIS IS MY 3RD TIME AFTER LUMPECTOMY CHEMO AND RADIATION 2ND TIME DOUBLE MASTECTOMY AND RECONSTRUCTION NOW CANER AGAIN.1999 2011 2023.DR. CAN NOT TELL YOU WHEN THE CANCER WILL COME BACK OR HOW LONG YOUR GOING TO LIVE

[@yerbba]

There is so much uncertainty with any type of cancer. In our experience, that uncertainty can be the hardest part of the whole experience. Thank you for writing.

[@Alexanderthegreatjones]

I hope the best for you and send prays and good energy

[@jml4774]

Are you talking about clinical staging or pathological staging? Does this information include people who have been treated with immunotherapy?

[@yerbba]

In this video, we were talking about pathologic staging. Immunotherapy, used for triple-negative breast cancer, will improve survival more than chemotherapy alone. The CDK inhibitors, used in high risk hormone receptor-positive breast cancers, will also improve the odds of remaining disease free. Great questions.

[@ibn_e_rasool835]

Hlo mam, Please tell me My mom is on breath cancer 4th stage But she was infected in many places also in brain And she cannot live without oxygen Tell me is there is any chance to treat him 🥺🥺🥺

[@yerbba]

Thank you for writing. I wish your mother were not so sick. It does sound as if she is struggling, in particular with the involvement of cancer in the brain and requiring oxygen. Her medical team is likely to recommend that she receive aggressive management of symptoms so that she feels as good as possible for as long as possible. Hormonal therapy may help people whose tumors are hormone receptor-positive. Please take care of yourself. Your mother is fortunate to have you involved in her care.

[@Ahmad_617]

Please use Fegonia arabica (dhamasa) herb for stage iv cancer.Inshallah she will benefit from it.

[@FatemaAkter-mq8yc]

What about Er positive pr negative her2 positive???

[@yerbba]

Someone with this type of cancer will benefit from both endocrine therapy and anti-HER2 therapy. In people with stage 1, 2, or 3 breast cancer, the goal is cure. Let us know if you have additional questions.

[@deniseyweesy]

Are all the missing dots people that died from only Cancer? Or did some die for other reasons?

[@yerbba]

The dots include people who die of other causes as well.

[@glitterwithFoodSaddy]

Want to know prognosis for ER PR positive her2 positive stage 2 A cancer with no nodes involved ,lumpectomy ,6 chemo rounds with including 17 rounds for hormone therapy plus radiation 20 rounds and now taking letrozole 2.5 mg .. worried for mu mother ,she is 72 .. chances for reccurence

[@yerbba]

Your mother is fortunate to have you. Given the treatment that she has had and the tumor characteristics you provide, it is more likely that she will not have a recurrence than she will.

[@dakshchinna]

dea..can I survive breast cancer if I start my treatment after 5 years from when I detected cancer and how many stages will be there n how many years it will take in each stage any idea🙏

[@yerbba]

Most breast cancer tumors respond to treatment no matter when treatment starts. In other words, I have had patients who ignored their breast abnormality for years. When we started treatment, most people have had a dramatic response. I should say that we do not recommend delaying therapy if your goal is cure. If your goal is to improve your quality of life, we can achieve that even if the cancer has been ignored in most cases.

[@dakshchinna]

@@yerbba 🙏🤍

[@isaacali8695]

Why does cancer become so aggressive after treatment. It takes roughly 7 years before it is found. Once removed you would expect at least 5 years before it becomes problematic but if it recurs it's like 10 times worst. Why?I believe it has nothing to do with the treatment.

[@yerbba]

It is remarkable that it can take tumors so long to develop and that, once they do, it can seem as if their growth is unchecked. Tumor cell behavior can change over time.

[@MamaVee50]

Triple positive grade 2.?

[@yerbba]

The prognosis is quite good in general for Stage II (2), ER/PR/HER2-positive breast cancer with a combination of several types of treatment. Please do take a look at our other videos about endocrine therapy, targeted therapy, and chemotherapy.

[@HL-qv3yd]

What about ER positive PR positive her2 negative stage 4 de novo breast cancer lung and bone metastasis? Please

[@yerbba]

Thank you for writing. It can be so hard to find statistics about breast cancer survival for people with Stage IV disease. The average life expectancy doesn't really mean anything because there are different kinds of breast cancer. With a hormone receptor-positive, HER2-negative breast cancer, people can live for many years...even decades. Of course, it's hard to say in a given person. It depends on how well your cancer responds to the first line of treatment, how symptomatic you are, and other things. Wishing you the best. Keep watching our videos for more information about Stage IV and metastatic disease.

[@HL-qv3yd]

Hi Doctor, thank you so much for responding my question, yes recently diagnosed with de novo er and pr positive, her2 negative breast cancer, I was very healthy person, accidentally diagnosed with stage 4 er positive since march, mentally I'm not coping well. I'm following all your educational utubes, thanks again your time. ❤

[@same5952]

Prolong your life at the cost of quality of life you have left. No thanks.

[@yerbba]

Thanks for sharing your insights. We happen to agree…quality of life is equally important to length of life. It's really the combination, isn't it?

[@gdwitch]

What about stage one estrogen positive, negative progesterone? I can't seem to get an answer for this.

[@yerbba]

Hi Lucille. If you are referring to an ER-positive, PR-negative, and HER2-negative, stage one breast cancer, the survival rates will be very similar to the ones you use in the minute 1:12 of this video. The NHS has a powerful tool that estimates survival rates for different tumors and treatments, called e-predict. You can find it here: breast.predict.nhs.uk/

[@gdwitch]

@@yerbba Thank you!

[@maritataylor3939]

What about triple positive?

[@yerbba]

Hello Marita - Tumors that are HER2-positive have traditionally been considered higher risk. However, with targeted therapy, the prognosis is as good as with tumors that are HER2-negative. In addition, the fact that the tumor you are describing is positive for ER and PR means that hormonal therapy is also of tremendous benefit.

[@mini8908]

Mam please tell about er and pr negative but her positive 3 breast cancer

[@yerbba]

Thanks for writing. Someone with a tumor that is ER- and PR-positive and HER2-positive will benefit from both anti-HER2 therapy and hormonal therapy. In general, anti-HER2 therapy is given with chemotherapy. This will be followed by endocrine therapy. Decisions about surgery and radiation therapy are separate from the decisions about endocrine therapy, chemotherapy, and anti-HER2 therapy.

[@monicaharry4777]

What about stage 3 c her2 positive

[@yerbba]

The goal of treatment with this type of cancer is cure. While we can never guarantee that someone is cured, that is certainly the purpose of treatment. With anti-HER2 treatments, the prognosis is so much better than it was before these treatments became available.

[@indiancitizen8297]

I have triple negative breast cancer...does that mean...I can't live long ?...I have two children

[@yerbba]

Triple-negative breast cancer, if it hasn't spread to other parts of the body, is treated with the goal of cure. While not everyone will be cured, cure is certainly within reach. Wishing you and your family all the best.

[@indiancitizen8297]

@@yerbba It hasn't spread to other parts of the body...I was treated first with Chemo, then surgery and then radiation... Radiation has started last week