Great recap of this new drug. I appreciate this. Learned so much.
@chaseme986029 күн бұрын
What about PD patients with the classic symptoms that have a negative Datscan?
@RobertMcKay-i9r2 ай бұрын
Desiree Unions
@haroldwhelan70262 ай бұрын
Ù
@NansyNasr-ou6wc2 ай бұрын
Does prucalopride worsen parkinson ? I have constipation bbcz of Parkinson's...does tgis medication worsen parkinson
@ADDH-zr1kw2 ай бұрын
Hello Sir. Could you please advise if the focused ultrasound is a one time surgery or does it need to be repeated after a few years. Also, please advise at which places in the US the focused ultrasound is available because this procedure is not available in my country.
@CynthiaFox-t6c2 ай бұрын
Bruen Crossing
@luisarodriguez34383 ай бұрын
Please open more spots for HMO plans I need my father to see you he has Parkinson 🥹
@digicourvoisier95454 ай бұрын
Best thing I ever did to control my Parkinson’s symptoms. Dr Rodriguez is amazing!
@TheParkinsonsDoctor3 ай бұрын
Thanks for sharing your experience.
@centralcoastcamper96314 ай бұрын
Amantadine gave me the worst nightmares
@donettarich37284 ай бұрын
Why is NPH, Normal Pressure Hydrocephalus, not discussed when considering other possibilities? This is an often missed diagnosis that more people need to be aware of and is reversable.
@cttxmN5 ай бұрын
Neurologically, what differentiates PD patients with hallucinations from those without? THANK YOU!!
@TheParkinsonsDoctor3 ай бұрын
Great Question. In my experience, people with PD hallucinations see people or animals but do not hear them. There is no "voice" or sound coming from what they see.
@danlowe86845 ай бұрын
Thank you for the information, doctor. Is Sundowner's Syndrome associated with Lewy Body disease?
@TheParkinsonsDoctor5 ай бұрын
Yes, it is fairly common, especially when admitted to the hospital.
@danlowe86845 ай бұрын
@@TheParkinsonsDoctor Can you please tell me the difference? The reason I ask, is that my estranged father was originally diagnosed with Sundowner's, then, later in life, and closer to death, was diagnosed as Lewy Body. FYI, he fell into his (wife) caretaker twice, once breaking her hip, and next breaking her leg.
@grannyflowers26375 ай бұрын
I appreciate the information. My husband is suspected to have MSA-P. There isnt a lot of information out there. Please keep the videos coming.
@TheParkinsonsDoctor5 ай бұрын
Glad it was helpful!
@michele03246 ай бұрын
Wouldn't pathologic evidence of alpha-synucleinopathy coupled with signs and symptoms of MSA be indicative of MSA versus PD and especially if the patient isn't responding to Levodopa?
@TheParkinsonsDoctor5 ай бұрын
Correct. Especially if no hallucinations.
@TurgenevTheGamer6 ай бұрын
Word to the wise: Antidepressant drug Wellbutrin can impact your results. Acc'd to GE, the protocol is eight day abstaining from the medication prior to testing. For me, this led to a diagnosis of early onset PD. However, I found a case study where someone with my basic statistics (45+, taking Wellbutrin and abstained 8 days prior) retested a month later (staying abstained) and tested normal. I retested under these conditions and also came up normal. (A subsequent PD test called Sin One was also conducted, with my biopsy testing normal.) Prior to the Sin One, i also cold turkeyed on the carbidopa/levidopa regimen; my doctor didn't recommend it, but agreed that is i didn't have PD, cutting off vs gradual reduction should show no physiological impact. I had a mild headache for a day. Another nail in the false positive coffin. My case is bring prepared for a journal publication and notice to GE for a recommendation of revision of the medication protocol need on further study. If you take Wellbutrin, or any drug that impacts your dopamine intake, and you test positive with the DatScan, abstain longer if you can, or couple the test with the Sin One biopsy as a parallel testing comparison. Hope this helps someone. I didn't want anyone to go through the hell I passed through before I decided to dive deeper.
@TheParkinsonsDoctor5 ай бұрын
Thanks for sharing. Yes, some medicines may impact the results of the DatScan.
@traxmom3 ай бұрын
Thanks for this information. My mom is on Sertraline which is also contraindicated for DaTscan, but I didn't know it until your comment caused me to go searching.
@mmyy116 ай бұрын
Hi doctor My mother has been suffering from Parkinson's disease for about 14 years, and in the last two years, she has been suffering from overheating of her body, especially her palms and feet. It feels burning in the legs and the closer we get with the tips of the toes, the burning becomes more intense. All tests related to diabetes and liver are normal. Could it be a problem of Parkinson's and is there a cure? Thank you so much
@TheParkinsonsDoctor5 ай бұрын
Sometimes people with off episodes may have this kind of symptoms. Are they related to the timing of medicine intake (levodopa)?
@scottlindstrom67437 ай бұрын
Just found your channel and hope it's ok to ask a question. I have symptoms that suggest MSA; loss of balance, falls, tremors, constipation, erratic blood pressure, tinnitus, etc. HOWEVER, I also have periods of days, weeks, even months with no or only occassional very slight symptoms, feeling 95% normal. I haven't found anything that addresses this. Is this common with MSA?
@TheParkinsonsDoctor5 ай бұрын
It could happen in early stages. Sometimes lack of sleep can exacerbate symptoms. See a movement disorders specialist. We can assess earlier if this is in fact the issue.
@scottlindstrom67435 ай бұрын
@@TheParkinsonsDoctor Thank for helping me on this. Since I made that post I've been through genetic testing and there were no markers that would suggest neurologic issues. I don't really know how definitive that is; my neurologist is difficult to set an appointment with. But it makes me wonder is we've been barking up the wrong tree.
@DeboraLeung7 ай бұрын
I was in the hospital 2x in the last month, and this was a constant issue. I need my C/L at 8, 12, & 4 and then a night time controlled release C/L at bed time. I also needed my heart medication to control my Supraventricular Tachycardia by 8 a.m. each day, or I would have a very high heart rate. This was also a problem in the ER. I also let them know that I need to take the meds 1 hr before or 1 hr after meals. I also had a situation where the nurse was supposed to get me up to use the rest room, so then they would help me sit up in a chair. The nurse came in and never came back…even when I pushed the call button. I had to wait 2 hrs b4 someone came. I brought meds w/ me, but they said my husband had to take them home. I finally was referred by a nice Dr. to the Social Services Staff who listened to my situation, and agreed to address the staff and Adm. regarding this inexcusable situation. I am hesitant about going to the ER or hospital again…
@traceytansley16598 ай бұрын
Thank you Dr for great video and information
@TheParkinsonsDoctor5 ай бұрын
Glad it was helpful!
@mohsinsheikh80769 ай бұрын
Hi Very nice and informative video . I would further appreciate some more information. If you could please elaborate on complimentary and alternative modalities like remedial massage, myotherapy, osteopathy, naturopathy, asyra, neurofeedback feedback, neuro rehabilitation etc. As I have witnessed people getting positive impacts from these therapies and better parkinson symptoms being managed well. Also the progression with them were at low rate Thank you
@TheParkinsonsDoctor9 ай бұрын
The plan is to discuss the alternative therapies looking at them objectively. I believe we need to do better with PD and alternative therapies along with conventional treatments may be a better combination than alternative or conventional treatments alone.
@mayracolon98629 ай бұрын
Good morning Doctor Rodriguez, This subject is very interesting because every research or article I encounter that PD and MSA are very similar. I understand there are different MSA for example MSA-C cerebellar and MSA-P parkinsonian. Is it possible that in the future a video of this topic can be discussed. Thank you
@TheParkinsonsDoctor9 ай бұрын
Definitely. Thanks for the feedback.
@alejandromendoza39169 ай бұрын
Thank you Dr. Rodriguez this was another presentation that was very informative. I really appreciate you providing as much information available on alternative treatments for Parkinson’s disease
@TheParkinsonsDoctor9 ай бұрын
Thanks for the feedback.
@tonypickup25056 ай бұрын
Thank you for this excellent video Dr Rodrigues. It’s very encouraging to hear from MDS’s who take a holistic approach to health. I’ve 😊just watched two of your videos and found them very interesting, educational and well presented. When can we expect your next one sir? Thank you. Tony, England. Ps- can you recommend a MDS in the uk that also has a holistic approach? 👍🙏😊
@manonday21139 ай бұрын
Is the new blood test available everywhere in North America? It’s not used yet in Canada. How do we know is it’s a 100% accurate? This blood test must be very expensive.
@TheParkinsonsDoctor9 ай бұрын
The test is not available yet, but seems to be the most promising. I’ll update when available.
@justahappylittlebunny26569 ай бұрын
I hear family members shouting my name . Looking through my bedroom window shouting at me .But my blinds and curtains are closed. My dog never moves and he is very protective.
@TheParkinsonsDoctor9 ай бұрын
Interesting. Auditory phenomena is less common.
@irisrodriguez-cavallo93869 ай бұрын
What if you combine the test to determine pd
@TheParkinsonsDoctor9 ай бұрын
Unfortunately, that will not be a 100% solution. Hopefully we will have something soon.
@alejandromendoza39169 ай бұрын
As always Dr. Rodriguez provides a very good explanation of tests and treatments coming to the Parkinson’s community.Thank you very much for your dedication to this disease.❤
@TheParkinsonsDoctor9 ай бұрын
Thanks for the kind words!! I appreciate the feedback!!
@KathleenMWilson9 ай бұрын
I'm thankful for all info
@KathleenMWilson9 ай бұрын
@@TheParkinsonsDoctor❤
@irisrodriguez-cavallo93869 ай бұрын
Thank you Dr Rdz
@TheParkinsonsDoctor9 ай бұрын
You are welcome
@kathrynaldrich544110 ай бұрын
Let's suppose a patient came to you with the following profile, I'd like to know what your next step would be? Patient X diagnosed with PD in 9/21 has a history of poor response to C/L. Receives weekly PT and SP services, exercises regularly 4-5 days . In the last 6 months, patient X has declined due to falling (at least 12 times, only once with minor injury),diagnosed with OH 12/23, incontinence (urinary all the time, bowel occasionally). Can't walk without rollator and has a pronounced leaning to the right. Speech and vocal changes, doesn't swallow unless cued by accumulated saliva, drooling. Patient X comes to see you and relates all this to you. What's your next step for patient X?
@TheParkinsonsDoctor9 ай бұрын
These cases are very difficult and as a physician, heartbreaking. Looks like you are a healthcare professional with your description. This is a general response of how I handle these cases. This is not medical advice. The lack of response to levodopa and the rapid progression suggests an atypical Parkinson syndrome if the cardinal symptoms are present, such as rigidity, bradykinesia and postural instability. You did not mention tremors. The presence of OH suggests an autonomic involvement. I would check MRI of the Brain to assess for NPH, maybe the Syn-One Biopsy to confirm the presence of alpha synuclein to confirm this is a synucleinopathy rather than a tauopathy (PSP, CBD, etc). Depending on the results, and lacking hallucinations, I’ll have the diagnosis. PT, OT, Speech, Diet, Meditation are critical. I’d recommend to Focus on quality rather than quality. I’m bringing a video Monday discussing the Syn-One Test.
@kathrynaldrich54419 ай бұрын
@TheParkinsonsDoctor Patient X has an appointment with you on 3/25/24 and Patient X is me
@KellySmith-m4b10 ай бұрын
Appreciate this video, Dr. Rodriguez. Helpful and informative.
@TheParkinsonsDoctor10 ай бұрын
You are very welcome!
@KellySmith-m4b10 ай бұрын
Thank you kindly for this video and explanation of expectations with regard to DBS surgery.
@TheParkinsonsDoctor10 ай бұрын
Thanks. You are welcome!!
@centralcoastcamper963110 ай бұрын
The type that progresses slowly! Which I wish I had!!
@TheParkinsonsDoctor10 ай бұрын
Focus on exercise and a good diet. Lifestyle is critical.
@loloburton590611 ай бұрын
My father is having severe delusions with retari and repinerol (sp?) my mom is going to wean him off of retari bc he has taken repinerol for years without hallucinating. He has had Parkinson’s for at least 10 years. Any advice for supplements while weaning him from retari ? Have you seen this combo cause bad delusions?
@TheParkinsonsDoctor11 ай бұрын
I would advise against stopping Rytary without the doctor's supervision. It may not end up well as I have seen in other people. Between Rytary and Ropinirole, in my experience, I have seen Ropinirole associated with hallucinations more than Rytary. You bring up a point, he has been on ropinirole for over 10 years, but his brain has changed and it is now more sensitive. I suggest you discuss this with the neurologist and come up with a plan for doing the medication changes carefully.
@johndutton367911 ай бұрын
I had Focused Ultrasound Surgery and it entirely abolished my Parkinson's tremors in less than two hours. Check out Tremor Documentary 2022. It is a MIRACLE. Fus is bilateral now as well. Keep up the good work Dr. 👏
@yerrasiva2394 Жыл бұрын
Hello Doctor. I have been suffering from Schizotypal PD and have almost 12 years of lost interaction from real world. Can i go for this simulation therapy
@TheParkinsonsDoctor11 ай бұрын
HMMMMM. Schizotypal PD? Do you mean Drug induced PD secondary to Schizophrenia medicines? I am not aware of a Schizotypal PD. DBS is best for Idiopathic PD and I would not recommend with any other type of PD, but an evaluation with a doctor experienced with DBS is the best option for you.
@jameslambert6665 Жыл бұрын
Thank you for your work. My wife had MSA-c. Symptoms started at 16. She lived to 44. More research needs to be done. We went through all of this, barely knowing anything. An MRI showed us that the Cerebellum was deteriorating, but anything more than that was up in the air. The National Ataxia Foundation has resources and information for anyone who needs help.
@TheParkinsonsDoctor11 ай бұрын
Agree. Thanks for sharing. I have many patients as you describe and it is quite challenging.
@babylegs196810 ай бұрын
Ive never heard of MSA in a 16 year old and to live for over 25 years@@TheParkinsonsDoctor
@vijaykumarjain1362 Жыл бұрын
Pl.suggest some treatment for MSA.
@TheParkinsonsDoctor11 ай бұрын
MSA is very challenging and the currently available treatments are mostly supportive. However, there is a new research study you might check as an option to participate. Check: alteritytherapeutics.com/investor-centre/news/2023/01/09/alterity-therapeutics-launches-ath434-phase-2-clinical-trial-in-the-united-states-for-the-treatment-of-individuals-with-multiple-system-atrophy/
@babitanarula7965 Жыл бұрын
Please make a video on difference between PDand NPH symptoms
@TheParkinsonsDoctor10 ай бұрын
Working on this.
@babitanarula7965 Жыл бұрын
Dr I from India 🇮🇳 my mother not having tremors but shaking body sometimes smell swallowing taste issue and also having regigty in musles doctors in India clinically diagnosis parkinson's disease and gave Livdopa is it parkinson's disease
@TheParkinsonsDoctor11 ай бұрын
Many symptoms you mention sound like Parkinson's disease, but other conditions might also present with similar symptoms. Check out the video on Atypical Parkinsonism.
@mandeepthapa4357 Жыл бұрын
Dr can drugs induced parkinsonism be curèd
@TheParkinsonsDoctor11 ай бұрын
Drug Induced Parkinsonism can be reversed over time.
@Nicholas-ut8nl Жыл бұрын
Can a person with Parkinson’s start experiencing hallucinations they stop taking their medications?
@TheParkinsonsDoctor Жыл бұрын
Typically no. If the hallucinations persists after stopping a medicine, it suggest that medicine is not the cause. It might be a primary condition (meaning not secondary to any medicine).
@jimmcconnell7328 Жыл бұрын
Hello Dr. Could you tell me if essential tremor can develop into Parkinson’s? And if so what are the percentages that do. Thanks
@TheParkinsonsDoctor Жыл бұрын
Usually not. There are a few cases of a genetic mutations that associate ET and PD, but generally, the answer is no.
@metubetomuch Жыл бұрын
Dr. Rodriguez, my wife was diagnosed with MSA-C in 2022 after 9 years of a Parkinson's diagnosis and a reversal of that diagnosis in 2018 when the DATSCAN showed nothing. She was told then that she was crazy, and she was making it up. Then a brain MRI for her hearing system showed signs of MSA-C. Lewy Body Disease sounds like MSA symptoms.
@TheParkinsonsDoctor Жыл бұрын
Lewy Body, Parkinson and MSA are all disorders of alpha synuclein deposition. For this reason, they are very similar. You need a specialist to differentiate them. Your story is very common, where most people with MSA were initially diagnosed with Parkinson.
@vanessawilson9294 Жыл бұрын
Thank you Dr!
@TheParkinsonsDoctor Жыл бұрын
Thanks for the message!!
@jeedsp2640 Жыл бұрын
Thank you 🙏
@TheParkinsonsDoctor Жыл бұрын
You’re welcome 😊
@normanrubenzer Жыл бұрын
ok doc, well said, so my wife is going into the dementia stage with parkinson, so are doc suggested going to a mds up in madison wis at uw .she is on and off every two hours with her meds. so her nuerologist sugested dbs. i understand this but i believe she has the lewy body dementia with her parkinson, im the care taker and i may have to retire early if the doctors cant get this halluciations under control. memory is becoming an issue. but what is weird is she passed her cognition test the nurse gave her which amazed me, i am not a doctor,but how can someone with signs of dementia get dbs surgery. maybe after the long process of testing her brain they will tell us no surgery. i'm scared that it is going to make her dementia worse not better, yes any advice would be thank full . have parkinson people had any inprovements with red light therapy not a cure but a tool to help them live a better life??
@TheParkinsonsDoctor Жыл бұрын
I am glad to hear you will be working with a movement disorders specialist. This is how I handle this. I ALWAYS perform a comprehensive neuropsychological assessment before DBS. This test may take up to four hours. The test really provides an idea about cognitive status. I agree with you, I am concerned about memory issues and hallucinations as you mention. I am bringing soon a video discussing Parkinson's Disease Dementia vs. Lewy Body disease. Be on alert.
@normanrubenzer Жыл бұрын
looking forward to it@@TheParkinsonsDoctor
@louieb.free--brainfoodfrom6107 Жыл бұрын
Dr. Rodriguez, thank you for this information.
@TheParkinsonsDoctor Жыл бұрын
You are very welcome
@carbonejack Жыл бұрын
I neglected to mention that my research site for the PPMI study is the University of Florida.
@TheParkinsonsDoctor Жыл бұрын
UF is a great place. I was part of the PPMI project when I was working there.
@carbonejack Жыл бұрын
Very well done video. No jargon, very user friendly. I haven't been diagnosed with PD. However, more than 15 years ago I noticed I was starting to lose my sense of smell. Over the years I attributed it to my sinus problems and various sinus surgeries. I also began to kick in bed at night, fighting off snakes and alligators. As time went on the dreams sessions got more intense, so much so that I threw myself out of bed twice, once landing in the hospital. I began reading about the significance of these conditions in relation to PD. Fast forward to now. I'm participating in a research project connected with the Michael J. Fox Foundation called Parkinson's Progression Markers Initiative (PPMI). I had a Dat Scan as part of the screening process and am awaiting contact about the next phase. I since have started to have rigidity and some trouble walking.
@TheParkinsonsDoctor Жыл бұрын
Hmmmm. You need to continue following up. Thanks for being a part of PPMI. We need better answers and that is a great project. I have about 5 patients in similar situations as you.
@michelebegg5073 Жыл бұрын
I am 54 years old. I just completed DAT scan. I am also beginning a clinical trial for a possible new medication. I am hearing conflicting information regarding beginning medication this soon, at my age. Is there a downside to beginning medication at my age? Should I hold off taking medication for as long as possible. Only symptoms are tremors in arms and legs, stiffness, gate is not normal. What would you suggest? Sooner is better, or hold off as long as possible, due to medication side affects?
@TheParkinsonsDoctor Жыл бұрын
This is how I discuss this issue with my patients. I aske them: How is your quality of life is being affected by your symptoms? How different lie would be if we can improve your "tremors, stiffness, slowness, walking, etc."? If the answer is that it owed be a major change, that could justify treatment. Every person is different. I am bringing a video soon about when to begin medicines for PD.