12.6 Substitution Reactions of Alcohols | Organic Chemistry

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[@ChadsPrep]

Thanks, Lydia!

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[@ChadsPrep]

Excellent!

[@stevenosorio3330]

nice video, keep teaching organic chemistry since is rare to see about this class

[@ChadsPrep]

Glad you like it!

[@jbmu4644]

Why is PBr2O- considered to be a good leaving group? Its hard to think that it would trade places with Br- since Br- is better off unbonded.

[@maz6107]

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[@SupremacyMM]

Our professor said that sn1 can only go through tertiary halides, explained by new studies that came out recently

[@ChadsPrep]

Hey Trevor! When it comes to predicting products of reactions we are usually giving the major products, but always keep in mind that minor products are still possible. Our understanding of chemistry is constantly expanding - I try to keep the content relevant to the majority of courses but always recommend you listen to your own professor as they will be grading your tests! Happy studying :)

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[@ChadsPrep]

Thanks!

[@roronoaz4lyfe1947]

Around the 3 minute mark, why does the molecule flip when the carbocation forms?

[@xSLAYtheWEAKx]

hey chad! do you have a video that covers the mitsunobu reaction? thanks for all of these amazing videos!

[@meandpickles6937]

This was so helpful!

[@ChadsPrep]

Excellent!

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[@elandebenjamin3143]

Nice

[@ChadsPrep]

Glad you think so.

[@brunodesoutter2300]

「こんなにいいとは思えない」、

[@ChadsPrep]

Welcome to the channel, Bruno.

[@rone7499]

you need to adjust the content

[@swadha3]

Is the zinc catalyst only needed for SN2 reaction?

[@ChadsPrep]

The ZnCl2 is needed for both SN1 and SN2. The combination of HCl/ZnCl2 is actually referred to as the Lucas reagent and can be used to classify alcohols as primary, secondary, and tertiary. The tertiary alcohols react the fastest followed by the secondary (both reacting by SN1). The primary alcohols react the slowest (by SN2), and the time for the reaction to occur allows for the determination. Hope this helps!

[@swadha3]

@@ChadsPrep Yes it does!! Thank you so much!!

[@ChadsPrep]

@@swadha3 You're welcome!