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Leukocytes play a central role in the body's defense, it is not surprising that defects in leukocyte function, both acquired and inherited, lead to increased susceptibility to infections and compromises our immune function. The pathogenesis of Leukocyte adhesion deficiency type 1 (LAD-1), Leukocyte adhesion deficiency type 2 (LAD-2), chronic granulomatous disease, and Chédiak-Higashi syndrome are explained.
Kumar, Vinay, Abul K. Abbas, and Jon C. Aster. Robbins basic pathology e-book. Elsevier Health Sciences, 2017. Kumar, Vinay, et al. Robbins and Cotran pathologic basis of disease, professional edition e-book. Elsevier health sciences, 2014. www.amazon.com... www.amazon.com...