2nd Hyperparathyroidism & Hyperphosphataemia - Prof. Dr. Tilman Drueke and Prof. Dr. Markus Ketteler

Prof. Tilman Drueke and Prof. Markus Ketteler present a tour d'horizon on secondary hyperparathyroidism and hyperphosphatemia in chronic kidney disease patients.
Dr. Tilman Drueke is Professor of Nephrology and Emeritus Editor of Nephrology Dialysis Transplantation (NDT). Prof. Drueke has published seminal clinical and experimental papers in the field of chronic kidney disease - bone and mineral disorders (CKD-MBD) over five decades:
Dr. Markus Ketteler is Professor of Medicine and Director of the Department of General Internal Medicine and Nephrology and the Department of Geriatric Medicine at the Robert-Bosch-Hospital in Stuttgart, Germany.
He acted as co-chair of KDIGO Controversies Conference on CKD-MBD both in October 2013 and in September 2023, and as co-chair for the KDIGO CKD-MBD Guideline Update 2015-2017.
The webinar, which is dedicated to the memory of Prof. Eberhard Ritz (Heidelberg, Germany), was recorded on June 27th, 2024.
Moderators: Prof. Dr. Marcus Säemann (Vienna, Austria), Prof. Dr. Dr. Stephan Schirmer (Kaiserslautern, Germany) and Prof. Dr. Gunnar Heine (Frankfurt, Germany).
Articles discussed:
Optimal Phosphate Control Related to Coronary Artery Calcification in Dialysis Patients.
Isaka Y, Hamano T, Fujii H, Tsujimoto Y, Koiwa F, Sakaguchi Y, Tanaka R, Tomiyama N, Tatsugami F, Teramukai S.
J Am Soc Nephrol 2021
doi: 10.1681/ASN.2020050598
Effect of Vitamin D and Omega-3 Fatty Acid Supplementation on Kidney Function in Patients With Type 2 Diabetes: A Randomized Clinical Trial.
de Boer IH, Zelnick LR, Ruzinski J, Friedenberg G, Duszlak J, Bubes VY, Hoofnagle AN, Thadhani R, Glynn RJ, Buring JE, Sesso HD, Manson JE.
JAMA 2019
doi: 10.1001/jama.2019.17380
Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline.
Demay MB, Pittas AG, Bikle DD, Diab DL, Kiely ME, Lazaretti-Castro M, Lips P, Mitchell DM, Murad MH, Powers S, Rao SD, Scragg R, Tayek JA, Valent AM, Walsh JME, McCartney CR.
J Clin Endocrinol Metab 2024
doi: 10.1210/clinem/dgae290
Effects of empagliflozin on markers of calcium and phosphate homeostasis in patients with type 2 diabetes - Data from a randomized, placebo-controlled study.
Rau M, Thiele K, Hartmann NK, Möllmann J, Wied S, Hohl M, Marx N, Lehrke M.
Bone Rep 2022
doi: 10.1016/j.bonr.2022.101175
KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD).
Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Update Work Group.
Kidney Int Suppl 2017
doi: 10.1016/j.kisu.2017.04.001
Vitamin D Metabolites Before and After Kidney Transplantation in Patients Who Are Anephric.
Jørgensen HS, de Loor H, Billen J, Peersman N, Vermeersch P, Heijboer AC, Ivison F, Vanderschueren D, Bouillon R, Naesens M, Kuypers D, Evenepoel P.
Am J Kidney Dis 2024
doi: 10.1053/j.ajkd.2024.03.025
Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion.
Centeno PP, Herberger A, Mun HC, Tu C, Nemeth EF, Chang W, Conigrave AD, Ward DT.
Nat Commun 2019
doi: 10.1038/s41467-019-12399-9