#50-Platelets contribution to Hemostasis, α-Granules, δ granules - (Dense bodies)

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After vascular injury, platelets encounter ECM constituents (of which collagen is the most important) and additional proteins (vWF being critical) that are normally not exposed when the endothelial layer is intact. Upon contact with these proteins, platelets undergo three reactions: (1) adhesion and shape change, (2) secretion (release reaction), and (3) aggregation.
Kumar, Vinay, Abul K. Abbas, and Jon C. Aster. Robbins basic pathology e-book. Elsevier Health Sciences, 2017. Kumar, Vinay, et al. Robbins and Cotran pathologic basis of disease, professional edition e-book. Elsevier health sciences, 2014. www.amazon.com... www.amazon.com...