8. Binary Data

Introduction to Sample Size Calculation
Training session with Dr Helen Brown, Senior Statistician, at The Roslin Institute, January 2016.
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These training sessions were given to staff and research students at the Roslin Institute. The material is also used for the Animal Biosciences MSc course taught at the Institute.
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A spreadsheet to carry out the calculations described in the presentation may be copied here: datashare.is.ed...
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*Recommended KZbin playback settings for the best viewing experience: 1080p HD
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Content:
Example
Study to determine if level of infection differs between calves challenged with a virus and control calves who are not
p1 = proportion expected in challenged calves = 70%
p2 = proportion expected in control calves = 10%
Rounding up - 7 calves per group are required to detect a significant difference with 80% power