A Compelling New Lupus Discovery with Jaehyuk Choi, MD, PhD

Northwestern Medicine physician-scientist Jaehyuk Choi, MD, PhD joins the show again to discuss another breakthrough in T-cell research. This time for lupus, a chronic autoimmune condition affecting 300,000 Americans that can cause inflammation in many body parts, including joints, skin, kidneys, blood cells, brain, heart and lungs. Findings by Choi and his Northwestern University Feinberg School of Medicine lab members not only elucidate the underlying mechanisms of lupus but also suggest potential therapeutic strategies.
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About Northwestern University Feinberg School of Medicine in Chicago, Illinois:
Our mission is to impact the practice of medicine through discovery and education to improve human health.
Choi has affiliations with and financial interests in Moonlight Bio. Northwestern University has financial interests (equity, royalties) in Moonlight Bio.

[@xredblizzardx]

As someone with Lupus this is amazing. Really hope we can do something about it besides nuke the immune system.

[@daviddawson4885]

Life-changing news for so many people, right now the focus is on Lupus, but it seems like all autoimmune diseases may find benefits from this discovery. Very grateful for the work of Dr Choi and his team and wishing them great success on their continued research.

[@claudiafalcao9166]

Amazing breakthrough 👏👏👏

[@emdeejay5515]

Terrific podcast! Dr. Choi is so well spoken and explains things well; he is a great interview subject. This is certainly an exciting breakthrough! The lupus and autoimmune communities are going to be thrilled at the prospect of targeting just the cells causing the disease (instead of suppressing the whole immune system, as we do now as treatment), let alone that the new treatment may result in healing wounds already caused by the disease. Absolutely wonderful news! I salute Dr. Choi and his research team (including the friend he used to play ball with! That’s a great story, too.) Thank you for the podcast- and the scientific discovery!

[@NUFeinbergMed]

We're so glad you enjoyed the podcast. Thank you!

[@KKing55]

Sign me up~!

[@mariajesusjimeno5685]

Ojalá de buenos resultados

[@jamesteahen5940]

This is amazing! Keep up the great work!

[@peggycrain8393]

It would be wonderful to have something that helps or cures Lupus that doesn't cause so many side affects that your quality of life sucks.

[@leavethemkidsalone860]

Sounds like gut damage is the root cause. Gut damage from toxins. I'm curious what the levels of plastics, metals, and other toxins are in the patients.

[@TheSensation19]

Another clinic I believe found a connection that damage in the gut can cause these molecule imbalances in the blood. However it is not clear what causes that gut damage. My guess is its more genetic than you think and less to do with lifestyle decisions.

[@leavethemkidsalone860]

@@TheSensation19 maybe genetics have been CHANGED from long term exposures, but seems like both. Lab tests confirm evidence of substances that should NOT be in a human or other animal. These substances DO kill beneficial microbes in the gut, allowing other items to be absorbed.

[@peggycrain8393]

How do you reprogram the cells?

[@SeventhSky1]

Sign me up for trial

[@highpointsights]

Why wasn't the fact that approximately 90 % of Lupus patients are women touched on??

[@angeladuvall7888]

Can I please be a case study?

[@heatherlorraine4346]

Came here to say this. Lol Third generation lupus warrior here.

[@9doyouknow09]

Please release that drug soon in any form.

[@Anurag-j2e]

Hey, loved the vibe🙌! I'm not really sure if it is the best time to ask but, I was wondering if I could help you create a better distribution by working on post-production like better storytelling through Edits, Keywords, think catchy intros and outros, or even some engaging short clips! Would love to chat if you're interested.