A Dummies Guide to Diagnosis of Intraductal Lesions of the Prostate

[@jeffrunning713]

I have been diagnosed with intraductal carcinoma and researching this form of prostate cancer. Thank you for your instruction.

[@rattarojwattanasirirux2629]

Outstanding lecture Sir; God bless you and your family

[@essamahmed9242]

Great, succinct and very helpful presentation. Thank you for posting

[@SandhyaRamachandran]

I like the tables and flow-charts; thank you for sharing.

[@rajalbshahExperturologicpath]

Thank you very much for your positive comment! I hope to bring more such informative presentations. Stay tuned.

[@imagedoctor]

Very informative and well explained. Thanks Dr Shah.

[@Simon-si3ec]

Really enjoyed this, will keep this video in my backpocket next time I see these intraductal lesions. Algorithm is very helpful.

[@rajalbshahExperturologicpath]

Thanks for the feedback!

[@theyeetboyz6838]

Very informative, very share more such videos

[@leeritz8368]

Another great lecture! Thank you for sharing your knowledge!

[@rajalbshahExperturologicpath]

Thank you, Lee!

[@DVenkateshMD]

Thanks so much for the presentation sir. It was lucid..pls share more such videos sir.

[@rajalbshahExperturologicpath]

Thank you Venkat very much for your encouraging comment. I have posted one more to the channel. Stay tuned for more informative videos.

[@yahyabouaichayahya6652]

Thank you very much for this great lecture, can you tell us please is there other signs that help us to differentiate intraductal carcinoma from invasive grade 4 carcinoma (other than right angle branching).

[@rajalbshahExperturologicpath]

Good question! The presence of confluent back to back mass forming glands, irregular infiltrative borders, perineural invasion, extra prostatic extension would suggest invasive process. In comparison discrete spaced out glands with irregular borders, right angle branching, partial gland involvement and two cells population (outer cells more larger and pleomorphic than inner cells) would favor intraductal carcinoma. This distinction however may not always be straightforward.

[@SandhyaRamachandran]

@@rajalbshahExperturologicpath Will IHC help in deciding in such cases?

[@lehu8529]

Just started my residency in pathology and this is VERY helpful, thank you! At 5:32 you talk about partial involvement of benign glands. I was wondering why this is not a major feature, since it seems to be kind of what defines IDC, in that it is an invasion of benign acini and ducts by malignant cells leading to a preservation of basal cells?

[@rajalbshahExperturologicpath]

That is a good question but technically HGPIN also may show partial glands involvement

[@SandhyaRamachandran]

Dr.Shah, what exactly is meant by Non-focal comedonecrosis please?

[@rajalbshahExperturologicpath]

Non-focal typically means 2 or more ducts with comedonecrosis

[@SandhyaRamachandran]

@@rajalbshahExperturologicpath Thank you

[@malinigoswami8526]

Very very useful video

[@rajalbshahExperturologicpath]

Thank you very much malini! I appreciate the feedback!