A user's guide to JAK inhibition for IBD

[@themcdougalbugle]

I’ve had UC since 2011. Tried all the biologics. Hope this works.

[@themcdougalbugle]

@Sara Daehn no

[@willk3915]

If this didn’t work for you what the heck is your next step ?

[@andreask5054]

@@willk3915 probably FMT... which could also be dangerous

[@andreask5054]

@Sara D. they already treated UC patiens in a study, I believe at UCSF, where a 40% efficacy has been shown, however only if pre-treated with antibiotics. So first gotta kill most of own gut microbiome, then seed a new one by FMT. No efficacy was shown in Crone's however.

[@andreask5054]

Google the French company Abivax. They have ABX464 small molecule coming up.