Abilify: Usage, Side-effects, Dosage and More

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Chapters
0:00 Introduction
1:58 side effects of Abilify
2:37 Warnings of Abilify
Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic.[5] It is primarily used in the treatment of schizophrenia and bipolar disorder.[5] Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism.[5] It is taken by mouth or injection into a muscle.[5] A Cochrane review found low-quality evidence of effectiveness in treating schizophrenia.[6]
In adults, side effects with greater than 10% incidence include weight gain, headache, akathisia, insomnia, and gastro-intestinal effects like nausea and constipation, and lightheadedness.[2][3][4][7][8] Side effects in children are similar, and include sleepiness, increased appetite, and stuffy nose.[7] A strong desire to gamble, binge eat, shop, and engage in sexual activity may also occur.[9][10]
Common side effects include vomiting, constipation, sleepiness, dizziness, weight gain and movement disorders.[5] Serious side effects may include neuroleptic malignant syndrome, tardive dyskinesia and anaphylaxis.[5] It is not recommended for older people with dementia-related psychosis due to an increased risk of death.[5] In pregnancy, there is evidence of possible harm to the baby.[5][11] It is not recommended in women who are breastfeeding.[5] It has not been very well studied in people less than 18 years old.[5] The exact mode of action is not entirely clear but may involve effects on dopamine and serotonin.[5]
Aripiprazole was approved for medical use in the United States in 2002.[5] It is available as a generic medication.[12] In 2019, it was the 101st most commonly prescribed medication in the United States, with more than 6 million prescriptions.[13][14] Aripiprazole was discovered in 1988 by scientists at the Japanese firm Otsuka Pharmaceutical.[15][16] Aripiprazole is primarily used for the treatment of schizophrenia or bipolar disorder.[4][5][17]
Schizophrenia
The 2016 NICE guidance for treating psychosis and schizophrenia in children and young people recommended aripiprazole as a second line treatment after risperidone for people between 15 and 17 who are having an acute exacerbation or recurrence of psychosis or schizophrenia.[18] A 2014 NICE review of the depot formulation of the drug found that it might have a role in treatment as an alternative to other depot formulations of second generation antipsychotics for people who have trouble taking medication as directed or who prefer it.[19]
A 2014 Cochrane review comparing aripiprazole and other atypical antipsychotics found that it is difficult to determine differences as data quality is poor.[20] A 2011 Cochrane review comparing aripiprazole with placebo concluded that high dropout rates in clinical trials, and a lack of outcome data regarding general functioning, behavior, mortality, economic outcomes, or cognitive functioning make it difficult to definitively conclude that aripiprazole is useful for the prevention of relapse.[6] A Cochrane review found only low quality evidence of effectiveness in treating schizophrenia.[6] Accordingly, part of its methodology on quality of evidence is based on quantity of qualified studies.[21]
A 2013 review found that it is in the middle range of 15 antipsychotics for effectiveness, approximately as effective as haloperidol and quetiapine and slightly more effective than ziprasidone, chlorpromazine, and asenapine, with better tolerability compared to the other antipsychotic drugs (4th best for weight gain, 5th best for extrapyramidal symptoms, best for prolactin elevation, 2nd best for QTc prolongation, and 5th best for sedation). The authors concluded that for acute psychotic episodes aripiprazole results in benefits in some aspects of the condition.[22]
In 2013 the World Federation of Societies for Biological Psychiatry recommended aripiprazole for the treatment of acute exacerbations of schizophrenia as a Grade 1 recommendation and evidence level A.[23]
The British Association for Psychopharmacology similarly recommends that all persons presenting with psychosis receive treatment with an antipsychotic, and that such treatment should continue for at least 1-2 years, as "There is no doubt that antipsychotic discontinuation is strongly associated with relapse during this period". The guideline further notes that "Established schizophrenia requires continued maintenance with doses of antipsychotic medication within the recommended range (Evidence level A)".[24]

[@princessscott1880]

I am diagnosed with major depressive disorder and Abilify has changed my life thank you so much Abilify nothing works like it😉

[@aarondibenedetto5908]

So glad to hear it. May you live a long happy life my friend.

[@milatripzonInstagram]

👆👆👆 deliver all kinds of 💊💉 to any location

[@alekplayzrobloxoof2890]

Same i also have MDD

[@N_toft]

Is it still working?

[@user-rz4ib8zb1z]

Same! Never seen my emotions so "regular".

[@oshixxxx]

Family member suffering from mental issues. This medicine is just amazing. From sitting outside supermarkets naked, to fighting the police, this one, made them normal again. It is expensive as fuck, but worth every penny.

[@adaptercrash]

That's a good one some changes within a month then side effect like aggression and stomach issues I took myself off it 30 days.

[@milatripzonInstagram]

👆👆👆 deliver all kinds of 💊💉 to any location

[@TH-lr9jb]

I already have stomach issues like IBS just wondering if you had anything like that . Prior to taking the ability

[@jacelaughter3859]

Bruh they got me on this shit for bipolar disorder and it is actually wild bro my heart be thumpin off that shit

[@jaydgonzales9879]

fr? they just prescribed me this for bipolar n im scared to take. what mg u taking?

[@JamesVestal-dz5qm]

I take 2mg of this medication in the morning. I dont know what it does. My doctor says it helps with thoughts. Its sort of like a stimulant. Im glad i dont have blood pressure problems. I go to the gym because i like having lower blood pressure. My doctor says abilify doesn't cause weight gain like olanzapine does. He's transitioning me from olanzapine to abilify so I don't have as much weight gain.

[@DrewZMan25]

as a child they over dosage my shit while i was in mental hosipotal

[@princessscott1880]

And I had no side effects from it☺️

[@milatripzonInstagram]

👆👆👆 deliver all kinds of 💊💉 to any location

[@Dnice85]

Wow that’s great no weight gain?! I want to take it but I’m afraid to my doctor gave me 2 mg yesterday and I’m afraid of the weight gain your comment gave me hope

[@danielmerlini7133]

The medication isnt that bad as long as you dont take 30 mg

[@kasperjensenzaelur6139]

Dident help got off after 3 months, agression got worse, gained 20kg, beain and thought out the window

[@10Tuxedo]

Did it happen to cause confusion for you?

[@kasperjensenzaelur6139]

@@10Tuxedo To a degree, but more of a blindsided confusion i was so aggresive that i couldent think straight not dumbfounded confused like i was going vegetable. Remind you this is 7 years ago just a rough explination from parents, experts and own experiences combined

[@neetusharma198]

Sir , Which is a more safest antipsychotic in diabetes for Schizophrenia in between Lurasidone or Aripiprazole ? Plz reply .

[@MedicalCentric]

Aripiprazole is generally considered safer for patients with diabetes compared to Lurasidone due to its lower risk of causing metabolic side effects.

[@neetusharma198]

Thanks

[@camoqueenie]

My doctor just prescribed me 2 mg of Abilify along with the 40 mg Lexapro I’ve been on for years . She said it will boost my lexapro a bit . I am not BP etc I’m just depressed a lil too much . And , I just want to know if anyone else is on same combo as myself ? Also has it helped you ?! Weight gain on 2 mg?! Etc . Thank u 🙏🏼

[@karenjimenez5815]

Same but I’m on 20 mg lexapro and 2 mg abilify

[@samanthagutierrez7354]

I love abilify however I will need the maximum dose I'm assuming

[@milatripzonInstagram]

👆👆👆 deliver all kinds of 💊💉 to any location

[@ethangellman4563]

It’s potent as fuck, I’m on 1mg for bipolar

[@paulflint6254]

On 5mg, seems to help @@ethangellman4563

[@sinniedagoat]

@@ethangellman4563potent in a good or bad way?? I'm getting prescribed for bp and I'm quite nervous to take it.

[@MMAxperience24]

I am on 5mg, i ll keep update of the consequences

[@fonzersbox1]

As a paranoid schizophrenic i was once hospitilaized and got risset that shit caused too many side effects worst thing was not properly swallowing food since no saliva for 3 months. I was in a mental hospital for 2 months. Also gained a lot of weight and it killed the boner as long as i was taking the pills. Oh and no joy in life from anything for a whole year which i don't know if it's risset fault or schizophrenia. Then they had to change it to abilify due to fast hearth rate and i needed another pill which would reduce the hearth rate problems. So 2nd time in mental hospital just for 2 weeks then and it works better than risset. I mean i lost 11kg just by going to abilify, boner kinda returned and there were some muscle tensions at 15mg of abilify but the psychiatrist decided to give me 10 mg abilify and i don't have the muscle tension anymore. Good thing i was only once in psychosis in my life and needed a mental hospital for that.

[@MedicalCentric]

I'm glad to hear that you've found some relief with the new medication and are feeling better now.

[@DrewZMan25]

it didnt help. just made me more depress and brain dead when around family kinda like fetynal

[@salaheddinboukraa4804]

May god heal you

[@maribelechevarria1484]

Abilifay para que se usa español

[@rogertaylor3951]

Antisicótico. Incluso para prevenir migrañas y cefaleas.

[@Jason_Amador]

I’m a schizo-Lifter

[@milatripzonInstagram]

👆👆👆 deliver all kinds of 💊💉 to any location

[@lestres5488]

Is it only in the form of a tablet? Can the tablet be melted and, or injected?

[@lestres5488]

Like a steroid?

[@sarahmitchell7038]

You’re crazy 😂

[@milatripzonInstagram]

👆👆👆 deliver all kinds of 💊💉 to any location

[@stephenroldan5107]

For what?

[@cymairah8102]

It can be injected with the instant shot

[@robertotorrres3332]

Bruh this shit is so annoying that my eyes go up because of abilify

[@salaheddinboukraa4804]

May god heal you

[@jamiemartinez5045]

Yo my p.o. saw that 😮

[@danielmerlini7133]

I hope that doesnt happen to me 😢

[@jessewilson1622]

It will kill you

[@danielmerlini7133]

Over time but it would take years i assume

[@rubbezahl3762]

Errmmm...have you tryied going aoutside??

[@MedicalCentric]

It's always a great idea to get some fresh air and exercise outside for overall health and well-being. ❤️