Acid Catalyzed Epoxide Ring Opening

[@inessa255]

the explanation of this was beyond phenomenal. thank you for helping me to understand! wish you were my professor

[@aryakaran2743]

This video is helpful after 6 years too.. thanks for providing the clarity of the topic and being on point... I have my exam day after tomorrow 🙃🙃

[@Clutchprep]

Glad it was helpful!

[@1314Fher]

This makes so much more sense now! Thank you so much T.T

[@sophiecantelope713]

THANK YOU this is what i needed, now where can I find the base catalyzed???

[@Clutchprep]

Hey there! You can learn that here: www.clutchprep.com/organic-chemistry/epoxide-reactions

[@melodymix9495]

Thank you

[@sweetness583]

I thought SN2 reactions didn't happen at tertiary carbons.

[@Danoroxursox13]

don't bases, such as Cl-, attack on the least substituted carbon?

[@tarunyadav2765]

Cl- will attack least substituted carbon when it is base catalysed. But in acid catalysed + plus charge on O is unstable so O will break any one bond (that will cause more + charge on carbon atom)

[@ramasamykuppusamy7974]

Is it sn2 or sn1 mechanism

[@Clutchprep]

Hey there! The nucleophilic attack will be considered SN1 since Cl attacks the more substituted side. :)

[@songoku362]

Why the nucleophile attack to the most substituted carbon atom

[@Clutchprep]

The nucleophile attacked the most substituted carbon atom because it has the most positive character. Hope that helps! :)

[@SourajeetSahoo]

How it has the most positive charge ?

[@songoku362]

​Due to inductive effect​ the density of +ve charge increases and makes it unstable which prefers for acid catalyzed reaction thus base attacks easily.@@SourajeetSahoo

[@SourajeetSahoo]

@@songoku362 due to inductive effect +I... positive charge decreases...

[@danielgladish2502]

Good video showing the arrow pushing, but the title says this is "acid catalyzed". You should have your acid reformed in the product no?

[@Clutchprep]

Hey Daniel! That's correct. Most of the time, mechanisms don't show catalysts being reformed anymore. I hope this helps! :)

[@estellaque8615]

Nice video... The olcohol tho 😂

[@Clutchprep]

Thanks! Happy to help! :)

[@phoenixll9858]

😍👍👍👍👍👍👍👍