Action Potential - Firing of a Neuron - Depolarization

[@harrisonbogursky6535]

wow you deserve the Nobel prize for most clear understanding of an action potential.

[@PsychExplained]

Much appreciated 🏆 😀

[@anetaratynska7278]

@@PsychExplained AGREE! I am doing a degree in neuroscience and can't understand a thing the professor is talking about. Very grateful for your videos!

[@clairewelsman1489]

Literally this!! Summed up everything that a 3 hour lecture confused 😊

[@_K.L]

OMG SALTY BANANA!!!!!!!!!!!!!!!!!!!!!!!!!! I literally constantly forget what’s high on the inside and what’s high on the outside. Now I’ll never forget. Thank you!

[@PsychExplained]

It’s all about the mnemonics 😊

[@_K.L]

@PsychExplained You're doing the LLOYDS work! Keep it up! Looking forward to watching more videos.

[@kristinbunch4741]

🧂🍌 Na+ K+ ATPase love your videos ❤ Dr. Kushner 🥼👩🏽‍🔬 this was so easy to understand because you draw it and break it down. Great graphics Salty Banana 🧂🍌 pouring salt all over the banana and remember -70 to +55 then resting

[@kaitlinirwin8575]

A banana in the ocean was the first one I heard!

[@swarnarekha]

1Simply resting membrane polarized 2Stimulus depolarize 3Polarity reversed rapid influx of na ion action potential 4 Permeability of na ion to outer membrane repolarization

[@meghankhebouz9032]

Kids are so lucky today! If I had these tools when I was in highschool, man.....Thank you for explaining these concepts!

[@PsychExplained]

Wonderful!

[@alyagha5600]

geniunely this is the best video I've seen on action potential. You made it so simple and I really appreciate that.

[@avadf8127]

rightttttt

[@PsychExplained]

Wow, thanks! 🙏🏻

[@kristinbunch4741]

I needed to draw a cartoon with the steps and your video made the HW easy! Easy steps great drawing and perfect memory techniques. Met and exceeds all expectations

[@dakshatakamble5591]

After years of reading AP over and and over, watching multiple videos, making notes for 1000th time.. this video finally taught AP without having to mug up😭😭🙌🏼🙌🏼

[@PsychExplained]

Happy to help 🤓

[@amandaacevedo9663]

YES

[@whitechair9293]

Well after studying that topic after a long time you already know the concept and this video just makes it clearer

[@tylerlupercio256]

Amazing Teacher, honestly not only did I learn more about Neurons but I also learned how to teach in a more clear fashion by watching how you explain things

[@PsychExplained]

Thank you so much for your kind words!

[@zuzannamikolajec8387]

THE BEST, most comprehensible explanation I've seen of this process. My immense gratitude.

[@PsychExplained]

Glad it was helpful!

[@mjob450]

OMG!!! thanks very much for this! I have never commented on any video on KZbin....but i think this video triggers me, it's well explained. THANK AGAIN!!

[@mariettevanjaarsveld4006]

This video is life-changing 😊! Thanks so much for the detailed drawing and steps!

[@PsychExplained]

So happy to help!

[@MsLowry207]

This is THE best explanation I've seen of this concept on youtube omg

[@PsychExplained]

Thank you 😊

[@lukes5102]

In physio psychology introductory class best explanation I have ever seen

[@kristinbunch4741]

❤😅right! Wish he was my profe!!!👨🏽‍🔬🥼

[@gingercoleman5719]

This is the only person who actually helped me understand this concept.

[@occam3064]

Yo I don't know if you still make videos but keep it up! I'm taking AP Psychology right now and you have hands down the clearest and most thorough explanations I have seen yet. It hits that sweet spot between simple to understand and complex enough to contain all necessary detail. Thank you and I would really appreciate if you were to post more.

[@PsychExplained]

Appreciate the kind words! It may surprise you but I teach high school AP Psychology. These videos are for you, and helping you earn that 5! Many more to come.

[@elleinfj1998]

@@PsychExplained 😊

[@ZainabNadeem-n9w]

I just finished watching the video, I haven't even opened my notes yet because this guy deserves this comment. BEST video ever, your page is my go-to. THANK YOU for explaining it so easily, my 1 hour and 15 minute lecture didn't explain it as well as your 12 minutes did!!

[@PsychExplained]

You're the best!

[@imel_diary]

The best video i have seen so far on action potential thank you so much.

[@PsychExplained]

Too kind. Glad it helped 🧠

[@jiujitsujudy]

I have been trying to understand AP for a year and I finally do now thanks to this video!!! Thank you!!!

[@PsychExplained]

That’s so great to hear! Happy to help 😊

[@rebecamendoza2017]

wow I was so confused on action potential and you made it so clear and understanding without using so much terminology! Thank you!!!!!!!!!!!

[@PsychExplained]

You're very welcome!

[@virtue1495]

Your energy is everything and so are your teaching skills! God bless you! Thanks a lot. Doing my nursing degree and needed to understand this well!! Everything you said helped a lot🙏🏾💕

[@PsychExplained]

Wonderful! Nurses are amazing. Enjoy the journey :)

[@adityasinghthakur7488]

My teacher took 3 hours to explain this and still I was confused, YOU ARE A GREAT TEACHER 🙌🏻

[@swarnarekha]

🎉🎉🎉🎉🎉

[@allisonfreeman6115]

This man was MADE to teach, God bless you

[@motivatemejas8118]

Your video in 1.25 speed was the best explanation of this process! Thank you

[@PsychExplained]

Glad it was helpful!

[@musselchee9560]

Fantastique! = +-+-+-+-+-+- ... I recently learned that due to a violent upbringing I have premature myelination and four other premature stuff that went on at a microscopic level within me. I was left with axons looking as if they were pumped up on steroids due to development adaptation. This vid has just given the nitty gritty to my external potential. Look out bad world, the Hulk lives. THANK YOU Doc.

[@annemeluch2276]

Again thanks so much for the detailed yet not overcomplicated explanations. The visuals really help me relate math and science together something I normally struggle with a lot.

[@FerryDzaack]

I went over this topic in my psychology book over and over and over and jus couldn't get it. 12minutes after watching this and I finally understood!! thank you so much

[@PsychExplained]

Excellent!

[@factuna6694]

Thank you for the very well put explanation. The only thing, however, you didn't mention was the sodium-potassium pump, which is what allows the neuron to return to the resting stage after being hyperpolarized!

[@PsychExplained]

Wonderful! Great pick up

[@Aboutdorna]

I love the way that you explain things ! a person who even dose not have science background can totally understand it and that is amazing ! keep spoiling us with your videos

[@PsychExplained]

Happy to help! 😎😎

[@marshmellow5344]

I'm a first year med student and this video helped me a lot!! Thank you for explaining very clearly. The banana reference is very clever. Now, I'll never forget the arrangement of ions during resting potential!

[@PsychExplained]

Wonderful!!

[@zareenaanowar9415]

confused myself over the slides for an hour and learned in your video within 12 mins. nice job mahn

[@PsychExplained]

This is awesome to hear 😎

[@lolimpoorhaha]

Thank you very much for me as a History student to understand the complicated “action potential” that had puzzled me long until I watched your amazing video 🎉

[@PsychExplained]

Glad it was helpful!

[@MeghanaPonnala-vq8gr]

I tried countless videos to try understanding action potential, THANK YOU THANK YOU SO MUCH

[@priscillalk5324]

This video just made me get fired up for my test ❤️🔥🔥🔥 thank you 🙏🏾

[@PsychExplained]

Love the pun!! Good luck 👍

[@ValerieRennon]

This makes so much more sense now! Thank you! I am taking psychopharmacology and sometimes the readings just blur together. The visuals and concepts used (salty banana and toilet refractory phase) just helps tremendously! I am now a forever subscriber!! Thank you- I will watch all your videos

[@PsychExplained]

Wonderful! Thank you for the kind words. Happy learning 🧠 📚 ✏️

[@JC-hu2nw]

Excellent ! Thank you for your clear, clear, and easy explanation. A BIG THANK YOU!

[@PsychExplained]

Glad it was helpful!

[@FelipeJrLeon]

Thank you for explaining it to me in simple and understandable way

[@PsychExplained]

Glad it was helpful!

[@sofiarojas2185]

This video saved my life. Thank you for all the work that you do!!

[@PsychExplained]

You are so welcome!🙏🏻

[@terryathena6508]

I'm a first year uni student and I've been looking for videos explaining this concept. This was perfect and really easy to grasp, you just gained a new subscriber. thank you

[@PsychExplained]

Glad it was helpful!

[@leonandresvalderramarico4449]

You are teaching me also English! Keep going men. Please more on statistics (null hypothesis, regressions) and physiology (muscle function, muscle damage).

[@PsychExplained]

More to come!

[@analinagarcia]

This man is a fxxxing genius. Ever so grateful for this channel!

[@shariqanida9492]

🎯 Key Takeaways for quick navigation: 00:31 *🧠 Understanding Action Potential* - Action potential defined as a brief electrical charge traveling down a neuron. - Neuron anatomy overview: soma, dendrites, axon, axon terminal. - Importance of action potential in neuron communication. 02:23 *🧪 Ion Concentration and Neuronal Resting State* - Neurons surrounded by ions: sodium and potassium. - Resting potential of a neuron at -70 millivolts. - Explanation of the "salty banana" memory technique. 04:01 *⚡️ Excitation and Binding of Neurotransmitters* - Excitation of neurons by stimuli like neurotransmitters. - Role of acetylcholine in binding to receptor sites on dendrites. - Opening of channels for sodium influx upon binding. 06:05 *🎇 Threshold and Action Potential Initiation* - Explanation of the neuron's firing threshold at -55 millivolts. - All-or-none principle: neuron fires when threshold reached. - Activation of voltage-gated sodium channels for action potential initiation. 07:54 *🔥 Depolarization Phase* - Depolarization: neuron becoming more positive. - Sodium influx leading to increased positivity inside the neuron. - Voltage change triggers the action potential. 10:04 *⏳ Repolarization and Hyperpolarization* - Repolarization phase: closure of sodium channels, opening of potassium channels. - Potassium efflux causing the neuron to return to negative polarity. - Hyperpolarization and refractory period before returning to resting potential. Made with HARPA AI

[@daisymarquez7668]

Taught me more than my professor in this video!! Thank you. Please more videos on nervous system or endocrine

[@PsychExplained]

Will do!

[@daisymarquez7668]

@@PsychExplained just finished endocrine. Thank you anyway! any videos on the cardiovascular or skeletal muscle?

[@PsychExplained]

@@daisymarquez7668 check out Siebert Science! He has great videos on these topics.

[@daisymarquez7668]

@@PsychExplained okay thank you!!

[@rengginangkhongguan]

Your explanation more clearly than my prof 😭 thank you , bless you teacher

[@PsychExplained]

Happy to help! 😇

[@SkyMeuangkhot]

Your a life saver i have a test tomorrow for AP Psyche about action potential and i didnt understand anything about it when my teacher was reviewing notes 😅 thank you

[@actuallynur]

THANK YOU FOR EVEEEERYTHING.I’m so happy that I found this channel.Please keep going 🫶🏼

[@annemeluch2276]

agreed

[@cecya5035]

Thank you! Love the analogies and the color coding. The explanation was very clear!

[@PsychExplained]

Glad it was helpful!

[@puritywanjiru3608]

The best explanation so far be blessed.

[@PsychExplained]

Wow, thank you!

[@peipewde6988]

thankx finally somone explained what cause the hypopolarization .

[@sofiamiranda5513]

You're an amazing teacher! Thank you for making these videos

[@PsychExplained]

Glad you like them!

[@jungandrea6060]

Oh my gosh! Thank you! I finally understand the concept!!!

[@PsychExplained]

So glad to hear! I love those “ah-ha” learning moments :)

[@CompassionateCaramel]

I just watched another video of yours. I wish I had seen your videos 3 weeks ago. Great job, best explanation.

[@PsychExplained]

Glad you like them! 🤓🤓🤓

[@tiyahirani4995]

This video has helped me so much with biology, thank you so much, such great help!

[@PsychExplained]

Wonderful!!

[@YollyM-to4hg]

Thank you very much, this is the best video and I now understand the action potential

[@PsychExplained]

You are welcome!🙏🏻

[@lyfeaskaitlyn2286]

Wow!! I love the way you teach. Thank you so much for making this seem so easily to understand. I subscribed to your channel.

[@PsychExplained]

Thanks for subbing!

[@carolmotta4704]

unbeliveble, how good are the explanations

[@ameliatahnia]

Thank you so much for this video! It was super helpful and the explanation was so clear. I hope you keep doing these educational videos :)

[@PsychExplained]

Thank you for the support!

[@croys8608]

Thanks! At last, I'm beginning to understand the process

[@PsychExplained]

Glad it helped!

[@msjay5747]

THE ABSOLUTE ABSOLUTE ABSOLUTE ABSOLUTE best explanation

[@PsychExplained]

Happy to help 😎

[@kiritoasuna5934]

I GENUINELY FEEL SO HAPPY WATCHING THIS THANKSYOU SIR this us genuinely the best of the bestes explanation ever

[@PsychExplained]

🤓

[@amandaacevedo9663]

this concept was always so confusing but this video really helped put everything in perspective! thank you🙏🏼

[@luna-ke3zv]

Thank u so much for these lessons as a polish nursing student 💉

[@unleashedcosmeticstv1253]

THIS IS THE BESTTTTTT EXPLANATION EVERRRRRRRR.

[@PsychExplained]

Aw thank you. Happy learning 😀

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This is what I've looking for weeks now 🙏🙏🙏🙏🙏 Thanks soooooo much

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You save my life. Thank you so much

[@PsychExplained]

Happy to help

[@stephanieknapaysweet7852]

😀 Thank you so much for the step by step. I went through so many videos and your video was awesome. Very detailed step by step.

[@nikhilrai2151]

beter than 2 hrs lecture of my teacher

[@PsychExplained]

Glad to hear!

[@zorodzaichari8811]

Wow the explanation is top notch 👌 thank you good teacher

[@PsychExplained]

Thank you! 😃

[@gojoswifeeyyy]

Salty banana literally saved my life! Excellent explanation!

[@PsychExplained]

So good!

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You deserve millions views!!

[@PsychExplained]

Thank you 🙏🏻 One day….

[@tehreemfatima5249]

you are the best teacher

[@DalalZada]

the best video ever thank youuuu so much this really helped me understand this lesson much better

[@PsychExplained]

I'm so glad!

[@mykaelaflores1683]

I did not understand this at all until I saw this video. thank you so much 😭

[@PsychExplained]

That’s awesome! Your neurons are firing 😎

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Wow it was jst like watching an interesting movie......interesting and easy concept clearance method.......awesome explanation of the terms and phases.....really loved it Sir thank u sooo much

[@PsychExplained]

Thank you so much 😀

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You deserve million likes

[@PsychExplained]

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THIS IS SOOOO WELL EXPLAINED

[@PsychExplained]

Glad it helped !!!

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Thanks you You made this easy . First time to understand it

[@PsychExplained]

Glad it helped!

[@lee_g9790]

eloquently explained, thanks a bunch!!

[@PsychExplained]

Glad it was helpful!

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This was absolutely Fantastic! Subscribed💪

[@PsychExplained]

Welcome aboard!

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Best explanation i found 😍... Thank u soo much

[@PsychExplained]

Glad to hear!

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I love you dude. saved my life

[@PsychExplained]

Love you too 😉

[@paulagar9140]

Love love love your explanations! Thankyou

[@PsychExplained]

You are so welcome!

[@syedajiniya5050]

Love this Doc!

[@PsychExplained]

Appreciate the message 😇

[@fazelahmad7320]

Thanks, good explination! But what happens afterward because this time all the K+ is outside and Na+ is inside. The normal position was the opposite (K+ were inside and Na+ were outside).

[@jk9-fr6xm]

asking the same question

[@PsychExplained]

Potassium channels open in response to depolarization, allowing potassium ions to move out of the cell down their concentration gradient. This efflux of potassium ions helps restore the negative charge inside the cell. Sodium channels that opened during depolarization begin to close, reducing the influx of sodium ions into the cell. This decreases the positive charge inside the cell. As a result of these processes, the ion gradients across the cell membrane gradually return to their resting state, with potassium ions predominantly inside the cell and sodium ions predominantly outside. This restoration of ion gradients allows the neuron to prepare for subsequent action potentials and maintain its resting membrane potential.

[@newmoonrain]

Why is the voltage at -70 inside at the start? If potassium is positive, what else is in the neuron that's so negative? Great video btw, thank you!

[@PsychExplained]

The resting membrane potential of approximately -70 millivolts (mV) inside a neuron at rest is primarily due to the differential distribution of ions across the cell membrane, particularly potassium (K+) and sodium (Na+), as well as the selective permeability of the membrane to these ions.

[@ninuriamarasinghe]

Thank you so much sir. This is so helpful and clear🙏

[@PsychExplained]

You are most welcome

[@roenschultz]

BEST EXPLANATION!! 🙏🏼❤

[@PsychExplained]

Glad it was helpful!

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Thank you ,,you earned a subscriber what a good explanation 😊

[@PsychExplained]

That's awesome!😁

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Saved me 🙏🙏 made something that seemed impossible to understand to now something I feel familiar with 😭

[@daemonkilla]

this was so helpful it’s been 3 weeks and i still didn’t understand

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Fantastic explanation!

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Wow you explained that so well! Thank you!!

[@PsychExplained]

Thank you for watching!

[@emaaneemaane7emaaneemaane7]

Really well explained 👍

[@PsychExplained]

Thank you 🙂

[@angelicarios9291]

you explain amazinggg omg thank you!!!!

[@PsychExplained]

Happy to help!

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This is so well made

[@deepalipimpale309]

Please make videos on sensation and perception.

[@Badrinath-u5y]

Amazing explanation !!!

[@PsychExplained]

Glad you liked it!

[@PsychExplained]

Glad it helped!

[@shwg3699]

I love you thank you for saving my grade

[@PsychExplained]

Love it !!😊

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thank you lord for this video. everyone else just rushes through it

[@PsychExplained]

So glad it helped!

[@AwethuNdunge]

Best of the best I know this process now thank you so much🙏🙏🙏

[@PsychExplained]

Most welcome 😊

[@flourishwithMJ]

Thank you so much. It's clear and exciting.

[@PsychExplained]

Glad it was helpful!

[@future-psych]

Thank you so much! Definitely a huge help!

[@PsychExplained]

Wonderful to hear!

[@anastone2014]

Very helpful! I subscribed

[@PsychExplained]

Wonderful!