Advanced Organic Chemistry: Accessing Enantioenriched Materials

In this installment of the Synthesis Workshop Advanced Organic Chemistry course, Dr. Mark Walsh joins to give an introduction to accessing enantioenriched materials.
References (in order of appearance):
Recommended reading: Organic Synthesis: Strategy and Control, Paul Wyatt and Stuart Warren, 1st ed.; Wiley, 2007.
See also: Chem. Rev. 1992, 92, 5, 935-952.
Org. Lett. 2000, 2, 25, 4041-4042.
Org. Process Res. Dev. 2022, 26, 9, 2629-2635.
For a review on synthesis and use of auxiliaries: Chem. Rev. 1996, 96, 2, 835-876.
See: Org. Synth. 1990, 68, 77 & J. Org. Chem. 1997, 62, 3, 454-455.
Org. Process Res. Dev. 2023, 27, 2, 343-357.
JACS Au 2022, 2, 2235-2250. Cryst. Growth Des. 2023, 23, 2837-2844.
J. Org. Chem. 1994, 59, 18, 5463−5465.

[@annikah9708]

Excellent overview, nicely explained and summarized, thanks a lot! One little comment: at min 31, the Jacobsen thiourea is actually drawn with an oxygen, making it a normal urea compound.

[@campbeja001]

Excellent presentation. Very organized and intuitive.

[@daretolive496]

Really excellent presentation. Learned something new and that Conglomerate Crystal technique was really fascinating

[@aidanlooby]

Really like this one, nicely done Mark!

[@SciEch92]

Nice work Mark! Hope things keep going great🍀