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Thyroid Cancer is different in different people. In prior videos, Dr. Clayman discussed advantages and disadvantages of removal of part of the thyroid gland, called partial thyroidectomy or thyroid lobectomy. In this video, Dr. Clayman discusses the advantages of removal of all of the thyroid gland in thyroid cancer surgery. For the most common thyroid cancers, surgery of the thyroid which removes all of the thyroid gland called total thyroidectomy provides the ability to treat thyroid cancer with radioactive iodine and the ability to watch the blood of thyroid cancer patients for the most common blood markers for thyroid cancer, called thyroglobulin (for papillary, follicular and hurthle cell cancers) and calcitonin and CEA (for medullary thyroid cancer). Total thyroidectomy may be the best surgery for thyroid tumors or thyroid cancers if there are abnormalities in both sides (lobes) of the thyroid gland or if you have a thyroid cancer that has spread to lymph nodes in the neck or the thyroid cancer has broken out of the capsule (or covering) of the thyroid gland. In this video, Dr. Clayman will discuss that total thyroidectomy may be the preferred thyroid surgery for thyroid cancers which have spread to neck lymph nodes, grown outside of the thyroid, or have spread elsewhere in the body as well as when thyroid cancers involve both sides of the thyroid gland and no significant normal thyroid tissue could or should be left in the neck.