AHS18 L. Amber O'Hearn - Inuit Ketosis and the Arctic Variant of CPT1A:

[@ThomasAT86]

Great talk and also good questions, absolutely fascinating topic!

[@KetOMAD]

It is weird that so much seems to be at stake here in terms of nutritional camps looking for historical support of a hypothesis. I like being in control of my metabolism and being able to test anything I fancy regardless of what may or may not have been true for the Inuit 2 centuries ago.

[@ShareefusMaximus]

It's important to me because my diet is meant to mimic what I believe the true paleo diet to be (See Miki Ben-Dor's talk). The only "modern" people on something similar are these arctic hunter-gatherers and the plains, buffalo peoples. If their diet is unhealthy, long-term then perhaps the paleo, ice-age ancestors didn't live long enough to see those long-term detriments. The Inuit are an important data point.

[@tomas387]

I just learned about the Arctic CPT1-A deficiency a few days ago and was a bit perplexed. Then I figured; since CPT1-B and C are working as they should in Arctic people - maybe CPT1-A was regulated down to allow more fatty acids to be metabolized directly in the muscles and brain and in the cold and hostile environment that outweighs the drawbacks (infant mortality rate and so on) of the ~22% efficient CPT1-A which btw is enough to fuel neoglucogenesis for the tissues that require glucose. I don't know, I am not an expert, just spit balling here. Also; what about cats? I remember reading that cats aren't in ketosis but rather derive their energy solely from neoglucogenesis. Now cats aren't humans but I mean, come on! Why is it that a pure predator is not in ketosis? That question is a pretty big fish to fry.

[@ropiakpawel]

Because they evolved on eating relatively lean zebras in Africa's savannas compared to us humans preying mostly for fatty mammoths during the Ice Age.

[@MarkWalsh418]

Nowadays Greenlanders are incurable sweet-tooths...the few slim adults that I see around are mostly smokers (60% of adults smoke) I look out my window here in Nuuk and it seems every second Inuit Greenlander I see (30 + yo) is apple-shaped / 10-30 kg overweight.

[@martinirving3824]

@Mark Walsh, Right, makes sense to me. I have a hypothesis that people who formerly had a high meat/protein intake as part of their natural diet, are easily corrupted into eating sugar and refined carbs once they are exposed to them. Not sure why that should be but one thought is both meat and refined carbs taste good and both are easily digested. This gives insight into why indigenous peoples are easily ruined by colonization from Europeans.

[@joerandom157]

​@@martinirving3824 could also be that they are metabolically broken from zero carb for so long that they just blow up like balloons if a challenge meal is thrown at them...

[@Bhaleri]

Just a small point, thought it’s not small to the Inuit, I’ll just mention that the word “Inuit” means “people.” So one doesn’t say the “Inuit people.” It’s like saying the “People people.” A single person is called an “Inuk”. Plural is “Inuks”. I’ve had all this explained to me in the Canadian Arctic, Nunavut, by Inuktitut interpreters. Not trying to nit-pick.

[@Jefferdaughter]

The traditional names of many, perhaps most, the various cultures around the world had for themselves meant 'the people' or 'the people of (a geographic feature or region).

[@michaelpagan3914]

Just like saying "nan bread". Nan means bread so you would be saying " bread bread"

[@michaelpagan3914]

Pagan is a name for "the native people" Later adopted as a descriptive of a non believer. But I'm not offended I forgive you all. Not nit knot picking!!

[@diablominero]

Have you ever heard of the Gobi Desert? Or the River Avon? English does this all the time.

[@user-yg1dg6xm2g]

Sounds like 'Eskimo' would be less complicated. Maybe we should go back to that.

[@MikeScott-c8h]

You say they only had berries for 3 weeks. Please research the Inuit preservattion methods and other intakes of carbs. I love your work but please include to better your research. Much love.

[@redbird1824]

During WW2 the American govt injected eskimos in Nome Alaska against their will with radio active isotopes in an experiment to see why they are able to with stand such cold weather.Many of them died early deaths from cancer.Sounds like some of the experiments conducted by Nazi germany on gypsies and jews during the holocaust.Makes me very angry! Especially since all they had do was ask an old eskimo and he would tell them.I've been to Nome a few times .The older eskimos would carry a flask inside their coats of coveted seal oil and put great stock in its emergency benefits claiming that if they ever get "chilled"[hypothermic]they simply swig down a shot or so of the seal oil and feel an immediate warming from the fuel.Somehow it kicks in quickly.Now I noticed when I started a high fat diet [I live in Alaska]that I could not tolerated much for coats or blankets at night for a couple of weeks.I'm not eskimo.Hope this helps.My internal furnace seemed to be burning hotter than usual.Someone needs to study the properties of seal oil.They had whale blubber but put great stock in the seal oil.

[@ragnarbeardred3450]

Zionist puppet

[@elizabethwinsor-strumpetqueen]

Very interesting , thanks for your comment, we have a high seal population here and I was looking at harvesting one or two a year as a food source. I have been carnivore for a month and already noticed a drop in my appetite and I eat smaller meals of high fat /proteins ...I'm going to get me a seal and see how that goes...any idea of how to extract the seal oil would be helpful ....if you can reply to this comment I will be eternally grateful. Don't know what the idiot below was on about ? the US is great at using us farmed humans to experiment on ...Mcdonalds is a great example ......

[@redbird1824]

@@elizabethwinsor-strumpetqueen Find an eskimo sounding name in nome and call them on the phone.A lady named Mabel is good[really it was a popular name 40 years ago or more]They will tell you.Old eskimos are very nice peaple.Young one too but they don't know the old ways.The first or second person you call will know WHO you should talk to.Concerning rendering fat though I am sure it is the same way one might render fat from any animal.Cook it in a large as pan as possible.Slow.The fast comes to the top.Watch a utube video on rendering fat from a hog-same thing.

[@user-yg1dg6xm2g]

Until we can confirm the safety of long-term, continuous ketosis, I choose to incorporate 4 tablespoons of honey daily into my diet, along with dairy and meat.

[@ShareefusMaximus]

Who asked the uncoupling question?

[@stevolukic]

And what the hell did he mumble? I didn't understand him because he doesn't know how to talk.

[@Paul--Nobody_Is_Out_To_Get_You]

Mistake in the description: "many cultures with a traditional diet of ...negligible carbohydrate". There have never been many cultures with negligible carbohydrate except possibly the Inuit.

[@Paul--Nobody_Is_Out_To_Get_You]

@@Jefferdaughter Masai had mostly milk which is more carbs than fat. Our ancestors had a big jump forward when they added meat to their diet and then another jump when they added tubers after learning cooking, all the while continuing with their fruit. So why restrict now? We are the result of very high nutrient plus very high energy consumption. It is a ridiculous false religion to restrict large parts of our diet and attempt to go back to an earlier hominid. And when you mention those two individuals and those selected studies fad is the word that comes to mind. You should free yourself of it.

[@pohkeee]

John Cheetham you are mixing issues. I didn’t hear anyone trying to convince others to personally change there diets. It is becoming very clear that because of incredibly mixed gene pools and mutations, the best nutrition approach is specifically driven by an individual’s needs. The speaker eats as she does because of her personal genetics and health history. There is no reason for anyone to take personal affront at what is scientific inquiry.

[@sarad6627]

@@Paul--Nobody_Is_Out_To_Get_You Milk drinking and the addition of carbs is a historically resent addition to the Masai diet. Jefferdaughter is correct. The majority of ancestral human populations didn't live off of fruit or a lot of plants. In almost all global environments, plants were available only for short periods. The European AMH populations ate 1/3 animal meat, 1/3 fish, and 1/3 plants which was only available in the summer. They spent long periods of time as carnivores.

[@jasonturner6459]

@@Paul--Nobody_Is_Out_To_Get_You Fruit was pretty much never a year long staple. They didn't have our domesticated giant sugar bomb fruits. They had seasonal very fibrous ones. The maasai consume milk, blood and meat pretty much. With by far most of their calories from fat

[@Paul--Nobody_Is_Out_To_Get_You]

@@jasonturner6459 Interestingly since my comment above two years ago I realise that evolution has failed as a theory and I believe in intellegent design ie God. Anyway it doesn't change the fact that fruit is very healthy and something we've always eaten and hasn't changed fundamentally - see Denise Minger's research into ancestral fruit.

[@Fjerid]

0:12 Peoples? Is this a word?

[@ZippyLikesZippers]

noun plural noun: peoples 1. human beings in general or considered collectively.

[@ladycactus110]

Yes

[@c4p4c1t1v3]

The Inuit are a fascinating people

[@biblebill6206]

We are meant to live of the land [plant based] not animal meats . There are exceptions to the rule like Eskimos who live in sub zero temp that's not you or me . They need a high fat diet they are an exception to the rule .

[@Greyfoxdbz18]

They aren't an exception to the rule, they are an example of the rule. The reason these people are used is because their diets are strict and tightly controlled so variables are minimised. And just because you can survive on plants doesn't mean you should. Plenty of vegans are weak and malnourished with uncontrollable cravings, fluctuating mood, hair falling out, loose, thin dry skin, mental issues like brain fog, teeth rotting. etc. Some of these issues resolve quickly after meat consumption is resumed. Especially the mental issues. Young vegans look okay but old vegans almost always look awful. We can survive eating plants but not thrive. Did you watch the video?

[@biblebill6206]

No , their an exception to the rule because they live in sub zero temps that's not most people . What % of people live in sub zero temps if it's very small then common sense would tell you it's an exception to the rule . Also , I agree being a "strict" vegan is very unhealthy and they do age faster .

[@Greyfoxdbz18]

@@biblebill6206 Why does living in a temperate climate mean that we HAVE to eat plants? we are still humans who requite meat.

[@biblebill6206]

Meat isn't a carbohydrate which is what the body's main source of fuel is . Look it up . Also , tell me why humans must have meat and do you mean red meat ? .

[@deskjockie4948]

@@biblebill6206 Glucose is the main source of fuel because humans nowadays eat mostly carbohydrates. This doesn't mean it's the best fuel for the human body. When carbohydrates are eliminated, the body goes into burning fat rather than carbohydrates, and many health benefits are experienced.