Alcohol Metabolism

[@swadeshicreator9717]

I m not a biology student but came here just for knowledge. It helped me quench my curiosity.

[@RobertSelig]

As always, another stellar video from a great world-class professor/doctor/teacher. But, of course, we can't forget about the cofactors needed to run the enzymes, such as zinc is required to activate alcohol dehydrogenase, and Mo is required in order to activate aldehyde dehydrogenase. So every molecule of Co2 must be converted into carbonic acid by the zinc-dependent enzyme carbonic anhydrase, which is needed to convert Co2 into CA.So once again, the minerals are critical factors to running our enzymes, and most of us are minerally bankrupt...

[@Hexose-bisphosphate]

He also mentions an increase of reduced nad promotes fatty acid synthesis but I’m pretty sure those coenzymes aren’t used but it’s rather nadph

[@diepnguyen-xg7yn]

The best video on alcohol metabolism. I know this video was about alcohol, I appreciate you mentioning that cigarettes smoking can cause ROS in the same pathway in the Endoplasmic Reticulum! Thank you!

[@rajadeepakragu1132]

I am 1st year MBBS in India (Tamil nadu) your lectures are very interesting and understanding sir☺️😇keep doing sir👍👍🔥

[@thethinkingman-]

do you have to go to school to be a doctor in india?

[@Matt0sh]

Hugely underrated video. Wish more biological/physical/chemical subjects were explained in more detail and in an easy to understand way like this.

[@busisiwesibindi3869]

Brilliant Video. So brilliant. It made me happy

[@ArtwithAshlyn]

saved my life thank you mustache man

[@zakirzak1494]

Superb explanation....👌👏👏🙏

[@martinzemba4319]

Nice work ,mate ! I love your videos.

[@mariaromolozano4875]

This video is GOLD. Amazing communication skills and perfect content! Really easy to follow. Congrats 🎉

[@julianallesgoncalves5541]

Thank you very much, I've finished the video with no more doubts.

[@marquese1960]

That was fantastic! I've been trying to get my head around what alcohol does to me--now I really know...thank you.😮

[@mahvishwani9512]

Thumbs up! 👍👍 Answered most of my doubts

[@MohammadRezaKhoshnam]

In one word: Amazing; Thank you doctor

[@Simplensweett]

U have made it very clear, simple and interesting.nice vedio

[@bigspaceshipgang9349]

You sir are a beauty and a genius my friend keep on keeping on

[@zeejimi4044]

I am a 68 year old male : 6 feet tall, and I weigh 12 stones (78 kg), that is I have a great BMI, and I play tennis and I walk my dog daily. I consumed alcohol regularly at a reasonable rate for years, and during a routine check-up both I and my doc were surprised to find out that I have a fatty liver. So, I chucked the poison completely as I came to the realisation that it was slowly killing me.

[@atlboy2002]

Great video Dr. Mike. Thanks!!

[@gelsayedpt]

You are great man thanks for your elite presentation of evidence

[@Pandamed-dr.b]

Thank you doctor Mike

[@itszahra4075]

I just can’t appreciate your explanation enough 🤩🤩 you make everything very simple

[@bullosunya5717]

The cutest glitch at “gram -ve” part😍❤️

[@assanilundindi5946]

Thank you Doctor Matt for making things easy to me.

[@archerhe4296]

Thanks mate, your videos have been great while studying Nutrition

[@ndagijimanafrankaimeerodri8893]

Thank you very much for this amazing video! I hope it helps me a lot as i prepare for my college exam !

[@glycolic001]

Exelente presentación

[@rezaurs]

Well explained! Thanks a lot

[@jerrykwame2603]

Excellent lecture. Thank you.

[@sw309]

This is a really good video

[@artsandbeauty]

Thanks for making it easy!

[@user-ih5pv5uw2i]

❤excellent explanation

[@suzyw8743]

Fascinating. I need some advice: In the last year, i've noticed that even after 1 small glass of wine OR 1 single shot of rum, my nose and cheeks go red and feels warm to the touch. I'm approaching 30yrs of age and this has never been an issue in the past. I'm assuming this is acetaldehyde after watching this video. My question though is how do i reduce this in the body? What advise would you have for me and others in my situation? I'm keen to detox the over production of acetaldehyde if you have any tips? Thank you!

[@user-yv9uw4dm9e]

What a great concise and informative video! Thank you:)

[@benjennings9314]

AMAZING CONTENT !!! I have a question. How long after ingesting alcohol does this take to normalise. Is someone has for example 3-5 drinks. Is there a rough answer you could give ? Thank you so much.

[@SoLoGLidez]

great watch

[@mohamedelouby1262]

keep going and all the best.

[@anakin1028]

this is so crazy good, thank you doc!

[@goodstuff4430]

its been a fast minute and u grew urself a nice stach!! Thnxs for all ur videos!

[@DrMattDrMike]

I'm quite proud of my new face caterpillar :)

[@ayushthetic]

What a great explanation

[@bl1n158]

nice moustache good 👍

[@blessedgreta6669]

Thanks for this, Twas really helpful

[@angilinajensen3088]

Fabulous.....thanks so much for this

[@hammettchemistry2914]

audio should be more louder....

[@Matt0sh]

You got a new follower

[@skysky6652]

Thank you

[@truthcooperator4683]

Great video, well explained. So 14 mg of pure ethanol in one drink, is it then 35 mg ethanol in 0,05 that is the driving limit?

[@violasiminabaraka8046]

Wow,thanks alot

[@user-ih5pv5uw2i]

This is a great video, because of this video I stopped my heavy drinking and understand why I cant lose weight, Is not only the extra calories but what happens to the whole metabolism process. I still need to attend events and have social drinks, so Doctor I have a question, After drinking, lets say 1 or 2 glasses of wine, how long will take the body to the normal levels of NAD? Thank you

[@doctorusmle1996]

Great work , Go On 😍

[@melvinbkruah3183]

Great video, I have learn a lot..

[@DrMattDrMike]

Melvin b Kruah thank you, Melvin! 😊

[@charlesterrizzi8311]

Almost as interesting as watching paint dry. I wanted to explore more in the area of the amount of alcohol that actually becomes fat in the liver. I understand it’s about 3% of the calories that can actually be digested in this way

[@michaelopoku4837]

Good video

[@nanak3363]

Really appreciated . Thanks. :)

[@DrMattDrMike]

Ramana thank you for watching! 😊

[@avanatroshy1257]

Thank you so much 🙏🏻💙

[@ClivehWright]

Great video, thanks.

[@synaruscz5352]

Wanna know if i metabolize fast alcohol (which is sign of liver functioning well) how does that resemble itself in reallife => do i become drunk after 1 beer imidiatly or do i have shorter drunkmind, or do i need more beers to be drunk - what are all sings of it?

[@Truthseeking]

I light up like Rudolph when I drink and get an incredible headache. Thanks, Asian ancestors I'm a social outcast!

[@shadimurwi7170]

Chicken eggs shell or chicken bones is a medicine for alcohol

[@davidcantu3872]

What's the best way to cure a hangover? Mix fruit juice since it has water soluble vitamins and minerals?

[@AcappellaGamer]

Something tells me Dr Mike has been pretty drunk coming home from the circuit party 🪭

[@assanilundindi5946]

Please Doctor Matt, iam struggling about Fatty acid oxidation, a video on this topic will assist me in my studies

[@thethinkingman-]

there was a lot of 'actual' facts mentioned here. remember they are the best facts, so try to remember them!

[@zaynab2255]

Thanks a lot 😊

[@elishahmartinez1452]

I need to stop drinking. Thanks.

[@Chimp993]

You video was interesting. I think I need your help for my drink driving charge from which I need to explain to the court that my double leg amputations have affected my metabolism from which I hadn’t Considered from blocking out my issue and using prosthetic and being consciously normal

[@darkmoon3646]

Thankyou sooo much

[@boatsandotherproblems5780]

I was told by my GP that my Neurosurgeon said my balance problems are caused by Peripheral Neuropathy (lower limbs), he allegely said I got that because I had my fair share of alcohol, I did have a good amount but my liver is OK, I have no Diabeties so what caused the Neuropathy? I started getting dizzy at about 75, I am 80 now and taking 50+ (that's what they are called guys) vitamins to repair the Myelin sheaths on the neurons in my feet and ankles and any Vertigo I once had has been treated and is no longer present and I know the absolute difference. I always assumed if I drink only until starting to feel happy it was time to stop thinking it has only now reached the brain, I thought 2 standard drinks would never get to my brain and nervous system.

[@BlowWord.]

the 50+ vitamins fixed all of that ?

[@carlorocky]

Myelin sheathing takes a long time to grow, but it indeed does regenerate. Things that are high in sulfur compounds like garlic, onions and egg yolks are your best friends, eat lots of them. Good health to you!

[@brianwise4571]

I work with folks suffering from alcohol addiction and It is so frustrating to hear "it's a moral failing" when it is clearly biology at play. I am not a Dr. of Medicine, etc...but that ius what it appears to be.

[@ximenalegorreta1615]

can the brain use ketones for energy?

[@alextv8975]

6:49 I'm confused on one thing. 0.7% is 14 times 0.05%, not 12. Is there another reason why you chose 12 and not 14?

[@0213mrdinero]

It’s 14.

[@imperialhistorian4201]

acetate or acetyl-coa? Is the acetyl-coa the final product and acetate is an intermediate product?

[@Hexose-bisphosphate]

Acetate is produced by acetaldehyde dehydrogenase from acetaldehyde. The acetate can form an acetyl coA by acetyl coA synthetase

[@Hexose-bisphosphate]

Because the enzyme is acetyl coA SYNTHETASE, it uses an atp molecule which is broken down into amp and a pyrophosphate

[@desertaxe]

this is my story 😥😥😢😢

[@dodododes]

ok what then if I have too much of NADH and need NAD+ what to do then what happens

[@azankhan88]

I have a question if anyone can answer this. How does alcohol gives energy/ calories when it's essentially getting converted to water and co2.

[@Hexose-bisphosphate]

The acetyl coA being produced could enter the Tca cycle releasing co2 molecules but also energy. Reduced hydrogen carriers could also be used in the electron transport chain to produce energy and water

[@azankhan88]

@@Hexose-bisphosphate thanks bud

[@Hexose-bisphosphate]

@@azankhan88 I’m not entirely sure tho, because if the level of nad decreases the tca cycle can not run properly

[@ShonMardani]

Is there a reason that nobody wants to mention the formulas? they are just C, H and O.

[@Hexose-bisphosphate]

He also mentions that Nadh is needed for fatty acid synthesis but it’s rather nadph

[@mikekirk1559]

thanks mike....but VERY QUIET MAN

[@nawfsidereviews6029]

He knew most of us would be hungover while watching this.

[@wmp3346]

You got rid of it

[@ExtremePacifist]

When exactly is an individual offically drunk? How many ounces of alcohol before one crosses that line? What blood alcohol concentration makes a person officially chemically drunk? .02? .05? .08? Until we can find that exact offical chemical measurement, we can not say consuming alcohol is acceptable. It is better that all of us promote, support, teach and practice abstainance from all mind altering chemicals, alcohol being the most harmful.

[@veganskeletons4131]

Alchohol is a blessing from God we just need to drink with a marry heart and moderation it's common sense.

[@ExtremePacifist]

@@veganskeletons4131 is God's gift of life to you notenough of a blessing? why alter your mind with man made fermented fluids that releases dopamine for a temporary feeling of euphoria, only to cause the brain to need more and more to feel that way again, hence the addiction takes over the addict.

[@veganskeletons4131]

@@ExtremePacifist did i not mention moderation? And are you calling God a liar? Don't you read his word? He said drink with a marry heart not be a drunkard.

[@mattsheezy5469]

I have the same thing except mine is for farts. Instead of telling you if you’re drunk, it tells you what you ate. My girlfriend gave it to me because she said she doesn’t fart...ever. She holds it in until it eventually travels out of her mouth. She doesn’t poop either, it’s the craziest thing. Apparently her body is 100% efficient at digestion. If she did happen to fart, it definitely wouldn’t stink, it’d be just like regular air. I don’t fart either, but that’s because I’m on methadone & it completely paralyzes the bowels. I have no clue where the food goes, it’s a miracle! Lord!

[@BlowWord.]

wtf did i just read …