Fat Digestion - Lipolysis & Lipid Transport

What happens to the fats that we eat?
In this video, Dr. Mike discusses how and where we digest lipids (triglycerides, cholesterol, and phospholipids) and how we transport them around the body.
He also introduces the lipoproteins and highlights the differences between chylomicrons, VLDL, IDL, LDL, and HDL's. Focusing on cholesterol management.

[@birdscrytoo]

this is hands down the best video on this topic, trust me I’ve looked. Thank you soo much!

[@michaelirwin1887]

Very good until the end when IDL and LDL exit the liver as plaque under the endothelium which further promotes the old argument of atherosclerosis and heart disease without any explanation of the original injury to the epithelial wall, which caused the injury in the first place.

[@user-mv8rw8hd6r]

In his words: fasting contributes to atherosclerosis. Nonsense

[@phanikumar4402]

Sir i really dont know hw to thank u ...u r really doing a great job ...everyday atleast once i think about ur lectures n u mean a lot in my educational career ...please do continue explaining many more medical topics so that students like us are likely to be much benefitted ....jus cant thank enough ...all i can do is blow lots of love peace and good health to u and ur family 🥰🥰🥰💝

[@grochef]

Thank you for the detailed explanation of lipid transport and digestion. Truly wonderful!! Since this video was created there has been some very important work done regarding LDL and Cardiovascular Disease. Please see Dr. Malcolm Kendrick's book, "The Clot Thickens". In that book he details the reasons why LDL cannot "deposit" on our arterial endothelium. Instead, it is the high pressure in the arteries and damage to the glycocalyx that causes the injuries that form clots, to which the LDL respond in order to REPAIR the damage.

[@KH3Art]

Dr. mike, you are awesome. The way you break everything down and explain the meaning behind the terms is amazing. So helpful, please don’t stop making these videos.

[@mostfuncked4551]

your videos have saved my butt! My professor has a tendency of saying things backwards or mixing things up. You are are so straight forward and have awesome diagrams that I can draw and follow along with. Your videos are the shortest and most helpful ones ive come across! a million times thank you!

[@dalidali2757]

THE BEST MD LECTURE ABOUT FAT DIGESTION I HAVE EVER WATCHED AND STUDIED ....

[@user-wb6je6mw5x]

you're literally my go-to channel in every lessons because of how you explain details into really understandable informations. Thanks a lot, Dr. Mike!

[@gina4168]

Amazing. Love how it starts with basics and then moves to details.

[@lawsonsimons-px8pe]

I have sent this to my professor and nursing friends! Incredible! Truly.❤

[@seokdoespilates]

Really really clear and helpful for someone who has little biochemistry knowledge. Thank you.

[@metsutai]

You are very clear and concise! Thanks a lot for your effort.

[@Demi-8]

Love uh Dr. Mike. You are a life saver, I have my final exam tomorrow

[@layaldergham45]

I literally never NOT skip ads but I watched this one because every Dr. Mike video I watch brings me closer to being a doctor of veterinary medicine! :) thank you dr mike for your help in finishing my degree!!! and you look so cute while doing it

[@kyms1862]

I have not studied since 2009 and gone back to university as a mature age student. Your videos are the most easiest to understand for and I really enjoy watching them! Please do more content!

[@jellycopter007]

Thank you very much for the fantastic lecture, very clear and easy to understand.

[@ktmilliken1860]

Excellent instructor. Explains things very clearly.

[@lanahamerlitz5926]

This was amazing, made me do such an amazing recap before my physiology exam

[@MA4TU2]

That was great. I learned more in 5 minutes than all the educational material I read. Well done.

[@neelo14]

Thankyou Doctor ,very helpful videos,short precise and to the point.👍

[@thatdancinggirl9882]

A round of applause. This video is a masterpiece

[@noeliaprietoschwartzman273]

Thank you for explaining so well.

[@yoe91]

5:05 - "So here's the deal OK the CCK tells the gallbladder to contract, thus squeezing the bile down the bile duct and squirt it into the duodenum". Dr. Mike: "PERFECT".

[@saadfallah1237]

Absolutely amazing, don't know how you manage to make it so clear and understandable!!

[@eyadakhras3521]

This is a brilliant summary; thank you very very much 😊

[@jkipoiuoty2]

The way u explain everything in detail is awesome. The clarity and explaining in simple words makes it so easy to understand. You are too good. Would love to meet u atleast once in my life ❤

[@estiakshakil2663]

You are just amazing sir,,,, love your teaching method more than say❤️.

[@melgu9355]

You are the best!!!!! Love your lectures.

[@Hamo4differentvideo]

Best explanation I ever seen

[@filmonhaile3327]

I rarely comment on youtube but you sir are amazing

[@deekircher21]

Great lectures ! Thank you

[@weddjammal9413]

ITS VERY CLEAR, VERY SIMPLE, didnt skip any important points. how can you do that!

[@abdullahahmed7604]

explained so well! thank you so much

[@zakirzak1494]

So nice and clear .... thank you 🙏

[@xlalouba]

Excellent thank you. Very informative and so well explained

[@Chipalo_with_a_c]

Honestly, amazing stuff!! Thank you.

[@zaarahussain3552]

Thank you Sir UR explanation is AMAZING.....

[@guest-zn8zs]

Wonderfully detailed video! Very nice

[@choonghuh]

feel like i just watched a christopher nolan film. so complex and so amazing

[@jaytran247]

thanks dr for the great lecture

[@anapaulacastro1534]

Muito obrigada! Amei a explicação. Muito boa mesmo. Consegui entender finalmente. Thank you very much.

[@alyaagamal5907]

Best explanation ever

[@lawsonsimons-px8pe]

Thank you soooooooo much! I had a hard time on this area.

[@kiranmayivemuri5813]

Thank you so much sir...very well explained

[@ilyaskhanilyaskhan4787]

Sir thank you very much for great lectures very clear and easy to understan💯👏👏👏

[@rogersssemwogerere5590]

This one has really worked for me good Job sir

[@treramirez109]

You are awesome! Thank you so much!

[@aldinstuart5787]

Excellent!

[@Hi-ny6iq]

you are amazing doctor thank you so much

[@mekonnenmengistu7332]

Great explanation

[@dodi8086]

You’re a supppppppppper star and life saver thanks

[@user-ix6wq6nj3i]

قمرر يا دكتور مات ❤️❤️شرح اكتر من رائع من مصر i love you♥️♥️

[@asuramunikavishadesilva371]

Thanks, sir!❤

[@whittenoval]

This guy is brilliant. Running out of superlatives now.

[@shohrehmousavi2090]

Thank you!

[@iaprawitasari3028]

Thankyou very much, it helps me a lot on learning biochemistry✨✨

[@sovannypond-tor8867]

thank you SO much

[@somasekhar4331]

Sir, it is a grate video. Even layman can understand your video. Request you to share similar video on ‘Digesting carbohydrates’ flow

[@eoinmcsweeney2632]

Love ur energy. ❤

[@user-oj3uj9uj3r]

amazing thanks a lot

[@doinagorenco739]

Thank you!!!

[@randdawoud5960]

you're the best i swear

[@martinford76]

This was very helpfull today ;o) thanks DrMike

[@ludelyntejada3239]

Thank you sir

[@foreverrainbow3566]

You definitely saved me. Thank you very musche

[@DrMattDrMike]

Glad I could help!

[@mrabin8098]

Best one!!

[@megburrows1398]

So good thank u

[@sanamsomani3404]

Please make video on bile duct injury

[@alaamohamed3211]

Thank u very much

[@Olivia-ck6jz]

فدوه شون شرح يخبل 😞💗💗

[@retnomurwani7226]

I like your video, I use it for my students. I was surprised seeing you with mustache

[@hschaufeld]

you're my hero

[@sakurabonita9905]

Please do a video on how vitamins ADEK fits in the process

[@Heisenberg.1927]

Concept 🔥

[@Loonapopyoutube]

youre my hero

[@DrMattDrMike]

🙈

[@user-qq9it4vn7p]

Wow doctor ❤❤❤❤

[@patriciamartin6309]

Brilliant explanation and thank you . I have a question . Does the cholesterol lay down in the blood vessels because the body signals that there is injury and it is trying to repair? The body always seems to have a reason ?

[@j7ndominica051]

Does medium and short chain enter the blood as triglycerides, and require for all 3 fatty acids to be short, or does it enter as free fatty acids and can be sourced from mixed triglycerides?

[@xeff3280]

Approximately where in the small intestines do to the majority of the lipids get absorbed by the enterocytes? Based on the structure of the Jejunum compared to the Ilium I figured this would occur mostly in the jejunum (because of the higher quantity of lacteals) but my A&P instructor says it's in the Ilium. I thought it was at the distal end of the ilium that the bile acids are reabsorbed not the lipids. The lipids were passed on earlier on in the small intestines. Can someone clear this up for me?

[@keep_scrolling.shorts60]

Ur way to teach : Excellet Ur looks : Excellent No. of times Im distracted by ur looks: Excellent. Btw Im really grateful to u for making this topic a tequila shot for me.

[@andrewnguyen5837]

Hello Dr.Mike, love your presentation video. I would like to ask if Lipases need to be active if the pH level is around 7.35 - 7.45?

[@doctorposting]

they wouldn’t be. hes saying they only work in basic environment

[@telegnes4500]

Love your tutorials. However, is the moustache real?

[@attahussain7559]

love from Sindh, Pakistan😊❤

[@effiechen1027]

If this can be added subtitle that will be perfect.

[@Catchfish201]

well constructed tutorial... thank you

[@janetmosquera4628]

I dont have a gallblader and is why i have bloating and gas depends on what i eat ??

[@Roozy_Persepolis]

So,does this.mean that when we fast for a long time,our LDL level goes up?

[@peterleighton4716]

If you fast more frequently, does this mean that you are at a higher risk for vascular disease due to very low density lipoproteins?

[@ntnjadeabdulhadi3386]

do you do online teaching ?

[@sanamsomani3404]

Please make video on varicose vein

[@DrMattDrMike]

Sanam somani will do!

[@DeltaSanjula]

So what happens to this process if the gallbladder is removed?

[@DaveMcCammon]

Wait a minute.. you said that when fasting you will produce more LDL cholesterol, which then is likely to be deposited in arteries and causes Atherosclerosis? This seems to go against the fasting argument for improved health amd longevity? Is this correct or am I missing something?

[@bigcat9977]

Is cholesterol the cause of inflammation? Or is it the first-aid that was delivered to the site of inflammation?

[@andywong8786]

No mention of the body's requirements for cholesterol. No mention of the effects of glucose on apoB100.

[@johnnyb620]

Could it be implied that people who are long term ketogenic adapters, will eventually develop atherosclerosis?

[@DrMattDrMike]

johnnyb620 too difficult to say. The current evidence says that increased saturated dietary fats + cholesterol will increase likelihood for atherosclerosis. However, there are multiple other contributing factors such as genetics, that are significantly influential.

[@mtofta]

@@DrMattDrMike This is old and outdated research. New research has proven that saturated fats are good. Why no mentioning of fats and ketone bodies as effective energy source?

[@GingerWaters]

I’m tryin to figure out how to turn my carb dominated diet, which causes constant battle against obesity, to fat + protein based diet. My body has 50 years of experience of using carb snacks every 2 hours to kick out the feeling of hunger. Now I noticed, that adding few centiliters of vegetable oil to coffee, kicks out the hunger for many hours. But it does not give instant feel-good affect, like carbs do. Then I started to prepare the sunflower coffee in tha shaker. The oil almost gets emulsified with coffee, and then the mouth releases:”oh yeah, this tastes food” hormone to body to take another sip, and another.. like carbs do. Now I’m wondering if emulsified fat turns quicker to glucose. Regardles if or not, I’m looking for simple way to emulsify sunflower. May be one micro drop of dishwashing detergent… That’s what I’m about to try once I have finished this comment. I tell the result in reply in hour or two.

[@GingerWaters]

Today my breakfast was: A cup of tea with 4 cl of sunflower oil first shaken without any emulsifier, and then adding a 1/100 of droplet of dishwashing liquid. Latter one made tea creamlike foody drink, which keeps the hunger away many hours. I’ve been fasting on/off for half year and now, once my waisteline is in harmony with my esthetique requirements, I try to learn to feed my body only to what I consume, to not make energy banks around the waste. Thanks for delivering information in very comprehensive manner.

[@Amelia-jk6bh]

who needs a cheeseburger when you can make us full

[@kimcruz3889]

soo. IS IT BAD TO FAST?? 😀

[@bellepie2027]

Does this mean when you fast, you increase your risk for cardiovascular disease because your liver produces more VLDL 🤔

[@MnrBugi]

So indeed, eating fats does not increase triglycerides in the blood as these are transported through the lymphatic system. Only in a fasting state, triglycerides are transported from the liver and hence in the blood. BUT doesn't this also mean, the body will be exposed to fat soluble toxins because they aren't sent through the liver? 🤔

[@drTERRRORRR]

Freddie in med-school?