Alvaro Martinez Barrio: Nextflow allows Pixelgen innovation engine to reach the market quicker

  Рет қаралды 70

Nextflow

Nextflow

25 күн бұрын

Alvaro Martinez Barrio
CDAO and co-founder of Pixelgen Technologies
Molecular Pixelation (MPX) is a technology that facilitates the study of relative location of proteins on the cell surface of single cells by NGS readout. During our talk we will introduce how this is possible using MPX and Pixelator, our dedicated software which we have developed within Pixelgen Technologies to generate data for protein abundance, spatial polarizaty and colocalization of proteins. We will also demonstrate how we use our Nextflow pipeline, nf-core/pixelator, to orchestrate data processing for customers and our internal R&D team.
In our publication, we demonstrate how DNA-oligo tagged antibodies coupled to DNA-pixels are used to assess proteins on the cell surface. We determine the relative location of these proteins by creating neighborhoods that are uniquely identifiable and interconnecting them in a two-step workflow. Based on the information readout, we build an in-silico graph that allows us to get information about abundance and relative location of constellations of proteins for 1000 cells simultaneously.
Pixelator is a software that transforms raw sequencing data into ready-for-analysis PXL files that can be analyzed with our data science tools in R and Python. To our knowledge, we are the first company to open-source our pipeline as part of the nf-core initiative and in this talk, we will try to demonstrate how this has benefited our customers and our core innovation engine.
Nextflow Summit - Boston 2024
summit.nextflow.io/2024/bosto...

Пікірлер
Roblox Innovation Awards 2023
35:10
Roblox
Рет қаралды 567 М.
Универ. 10 лет спустя - ВСЕ СЕРИИ ПОДРЯД
9:04:59
Комедии 2023
Рет қаралды 1,3 МЛН
Rob Syme: Practical Data Studios
28:18
Nextflow
Рет қаралды 195
Dr. Manil Maskey,  AI Lead, NASA
46:23
BIFOLD Berlin
Рет қаралды 32
INVENTIONS THAT WILL SOON CHANGE THE WORLD ▶3
18:23
Innovative Techs
Рет қаралды 5 МЛН
Don't Contribute to Open Source
9:55
Theo - t3․gg
Рет қаралды 217 М.
AMAZING Budget Handheld!  // R36S Review
14:12
TechDweeb
Рет қаралды 93 М.
I Quit My Job as a Data Scientist
12:31
julia fei
Рет қаралды 565 М.
Paolo Di Tommaso: What's new in the Nextflow ecosystem
42:49
Карточка Зарядка 📱 ( @ArshSoni )
0:23
EpicShortsRussia
Рет қаралды 788 М.
Мечта Каждого Геймера
0:59
ЖЕЛЕЗНЫЙ КОРОЛЬ
Рет қаралды 1,4 МЛН