ANION GAP | Ridiculously simple

[@AndreaJoseph]

Note : A LOW ANION GAP is very rare. If an electrolyte test shows a low anion gap, a doctor will usually order a second test, as the results may be due to a laboratory error. Hypoalbuminemia is one of the major causes of low anion gap. Hypoalbuminemia is when a person has too little albumin in their blood. Albumin is an essential protein. Hypoalbuminemia usually occurs because of inflammation in the body. Causes of hypoalbuminemia include: * sepsis * recent surgery * Malnutrition * severe burns * liver or kidney disease Hypoalbuminemia is also considered a contributing factor to having a low anion gap in people with multiple myeloma.

[@ryngkatdohtdong1408]

❤️❤️❤️❤️... Tq for the beautiful video

[@MeBeCarina]

it's almost 2am and I had been having a small mental breakdown over this topic for my final in pathophysiology the day after tomorrow ... this video literally SAVED me rn! I acutally, finally understood what this was all about! Thank you

[@the0master200]

oh my god! I am a surgical resident in the third year and I never understood this topic, ever. from med school till this day. today I finally understood it. thanks.

[@rufaiadamu957]

It's explicitly clear and simplified. Thanks a lot.

[@kridswonderhowell4541]

Bravo! Excellent content! Easy to understand & brief enough to hit the major concept! CINCH BY THE INCH-HARD BY THE YARD

[@basimjoseph295]

This was great... Had problem understanding this for long time...appreciate it

[@brunobittencourt9761]

Wonderful video, i was lost in this subject. Thank You for the light.

[@caioplays5542]

I love you, you help me a lot in my biochemistry test! Thank you so much

[@ernestenyan8676]

This is awesome….thanks for making it easy to understand

[@kashmalahadi7198]

Mannnn that was superbbbb!!! Loads of loveeeeee!!!❤❤❤❤❤❤

[@LouisMCollins]

This helped me understand Anion Gap. Thank you so much! 🙏🏾

[@paulbieber7103]

Excellent video. Simple, straightforward and informative. Thank you.

[@AnicaSuki]

you are so talented teaching! you made such a difference on my study! thank you so much and keep creating please !

[@AndreaJoseph]

You are too kind , thank you so much.. 😊

[@knraoneurosurgery]

this is called giving clear concept

[@abhineetgupta1827]

Such a underrated channel

[@naumankhan2872]

You are amazing maim❤️ Keep hard work one day you will cross 1M InshaAllah

[@danielcortes3278]

excellent video. Constructive criticism, your equation should be written with parenthesis as follows NA - (HCO3 + Cl) = 0 without it , the result is different great video again

[@razvanungureanu6305]

Congrats! Very simple and useful! 👌

[@daze8326]

Excellent presentation and great information!

[@tomterific390]

I've read that an increased anion gap can also result if unmeasured cations decrease (e.g. hypokalemia, hypocalcemia, hypomagnesemia) or unmeasured anions increase. The former (decreased unmeasured cations) is especially confusing, because how can a calculation only involving MEASURED cations be influenced by changes in cations that are NOT measured??? Makes no sense to me, unless those conditions are obligatorily associated with an increase in the measured cation.

[@elifsarsoy5175]

The last example frankly confused me. How does chlorine increase and bicarbonate decrease when the anion gap is in the normal range? Is there no acidosis in the last sample?

[@naeemmalik8952]

Wow just wow man❤❤❤

[@wtficantgetausername]

jeez that was ridiculously simple CHEERS

[@samm9993]

You described the concept so well. Shukria

[@nadia7238]

Thank you for the information. I do not find much info if the anion gap is very low, lower than normal range.

[@AndreaJoseph]

I’ve just written briefly about low anion gap .. it’s pinned in the comments section of this video ..

[@Monika-mb6jh]

I’m confused by one thing though.. if the high anion gap acidosis has an electro neutral serum as opposed to an acidic one… how do you know the person is in acidosis? And why would it even be classified as acidosis if the person has a normal serum pH?

[@atmshuvo44]

Electro neutral doesnt mean an even pH.here only ion gap are discussed not pH.

[@justinfarmer1933]

Great video! One thing to mention however is the formula should be Na (+K) - Cl - HCO3... or ... Na (+K) - (Cl + HCO3). Basically, you have to Subtract the amount of chloride AND bicarb from the amount of sodium.

[@ebubejosh2573]

This is the best video explaining this 💋💋💋💋 I just subscribed too

[@satadruray9787]

Really, really excellent. Fantastic

[@ladyvirgo013]

My lab work says 9.2 is low. I'm a bit confused. How do I raise it?

[@mahaqalbani4867]

Thank u so much. Plz add more videos particularly abt electrolyte imbalances

[@hassamghazi]

The best explanation!

[@dr.leelaram]

Really concept is cleared now❤

[@amatulnoor7171]

You are a saviour. Pls make more videos

[@elsiehyunjoonam9991]

Loved this video! Thank you!

[@cvsheshadri7376]

Nice explanation with figures👌

[@MA-qe6it]

Isnt it Bicarbonate re absorption from Proximal convoluted tubule impairment? In Type 2 RTA at 5.25 ? Pls correct me if I am wrong

[@AndreaJoseph]

Hello, thank you for your question. You’re very right that in type 2 RTA bicarb absorption in PCT is impaired ( also called proximal renal tubular acidosis ), but the video speaks about type 1 RTA - the most common type of RTA. In type 1 it is impaired in DCT .. it’s also called distal renal tubular acidosis .. Hope that helps :)

[@NavneetKumar-fs9nz]

Thankyou very much.You have explained it very well.

[@barakatullah1035]

excellent explanation.

[@vivekbio11]

👍 great...thanks for amazing presentation.....

[@silk.spectre6606]

Wow, I watched it once and learned it. Thank you so much for this video!

[@cynthiaoliver4469]

Does d plus or minus 4 mean that potassium is added and subtracted from d answer?? That is 12? Since the concerntration of potassium is 4meq/l??

[@AndreaJoseph]

It means that the range is either plus 4 or minus 4.. it’s just a range. 12-16..

[@প্ৰাণপ্ৰতিম]

Nice explanation mem.Thank you.

[@soumitrabhattacharyya6709]

Loved the video..finally understood

[@tommansoor5230]

i have high anion i have 18 what can i do to mack it 12

[@divyabharathiak422]

Wow.Really explained very well😊

[@drawesome9317]

hey whatever slides u use pleasse upload them as a pdf on ur telegram channel

[@philistinezigurath1368]

if the serum is always electroneutral why is it acidosis? acid is neutral?

[@rajeevkaparthi190]

Bicarbonate buffer system in the body tries to keep the pH with in the normal range but only to some extent. If the accumulation of organic acid continues BBS can not normalize the pH beyond its capacity. Hence, there will be acidosis. Meanwhile, the concentration of bicarbonate falls as it neutralize H+ .But, electrical neutrality is maintained due to accumulation of anion component of organic acids.

[@andrewsalas1154]

Very informative video! My results just came back and my Anion is 5 which seems a bit low. Should I be concerned? What is the best way to increase it? Thank you

[@ThatsWhy-]

Take sodium ....maybe you got multiple myeloma so phlebotomy

[@nbsecm3482]

Have you found out why you have low level of anion gap?

[@andrewsalas1154]

@@nbsecm3482 yes it was the steroids they gave me in the hospital for covid. That effected the levels from being accurate in the test

[@loregasmic]

​@andrewsalas1154 How did you find that out? I had a low anion gap and I'm trying to meet with an oncologist to test for multiple myeloma because I also had a back injury recently and that's a symptom so I'm thinking it's that.

[@andrewsalas1154]

@@loregasmic this was a few years ago and I cant recall what caused it now but I believe it was something that caused my charts to be inaccurate.

[@aSm8full]

finally it make sense now, Thank you

[@lola-mo5sh]

thank you. concise and very clear..

[@abhinavajith92]

I have understood what you've explained in the video but what is confusing me is this line from Ganong "This gap, which is something of a misnomer, is the difference between the concentration of cations other than Na+ and the concentration of anions other than Cl- & HCO3- in the plasma." And then it says it consists for the most part of organic acids,protein, Sulphuric and phosphoric acid. So according to that definition shouldn't it be Anion Gap= [Anions-{Cl+HCO3}] - [Cations-{Na+K}] I'm not able to wind my head around this

[@abhinavajith92]

Ooh i think i got it Using the graphic at 1:52 So Na+(other) Cations = Cl+HCO3+(other)Anions For electroneutrality And thus (other)Anions-(other)Cations = Na-Cl-HCO3? Am i right? This kind of makes sense to me now

[@AndreaJoseph]

Anion gap is indeed a misnomer. Because it’s a concept created by us. The term ‘unmeasured’ is really a misnomer , as many of these anions and cations are actually Or can be measured , however they are not included in the anion gap equation (and are ‘unmeasured’ for this purpose). So in reality , in a healthy body there is no gap. Humans have created the concept for our convenience in diagnosis . Hope this clarifies it for you !

[@abhinavajith92]

@@AndreaJoseph yes thank you ma'am

[@jocelynsalmeron733]

Great video !!!

[@benh7274]

Thank you, that video helped a lot!!

[@dr.nazninahmed1361]

Thanku so much for this wonderful video..ur new subscriber❤❤

[@elahedead6357]

Brilliant, I just learned

[@abdallahabdelrahman2224]

عااش nice video 💜

[@dr.leelaram]

Very good👍👍

[@nursingbeats8467]

Mam your content is drop dead gorgeous and neat cute easy understandable Mam I need explanation about base excess put one regarding one video mam

[@meowismeify]

Why doesn't this video mention a Low Anion Gap?

[@AndreaJoseph]

I’ve just posted in the comments about low anion gap ..it is pinned in the comments section ..

[@Vinodbukka]

Explain NAGMA with Urinary Anion gap madam

[@riteshchaurasia4953]

If u could explain more detail in case of vomiting..

[@chhotu5643]

Please more videos

[@harshamaloo2080]

Did you take this from vivek sir’s physiology

[@AndreaJoseph]

Oh I’m sorry I’ve never watched his videos! I’ll check them out. I took inspiration from Hippocrates KZbin page, and the book guyton.

[@marklotfy7706]

Perfect! Thank you

[@divyaatri8651]

Awesome video

[@momeenamaheen.5837]

very informative

[@blackbirds4]

what about an Anon Gap of 6 what does that mean?

[@AndreaJoseph]

Thank you for your question . That depends on the lab we’re using to test the anion gap .. it could be in the normal range .. it’s explained in the video @ 2:50 Because some labs calculate sodium and potassium whereas some others do not include the potassium value ..

[@cynthiaoliver4469]

Tnk u soooo much! Great video♥️

[@mounotashopno5113]

Amazing❤️‍🔥❤️‍🔥❤️‍🔥❤️‍🔥❤️‍🔥❤️‍🔥 from Bangladesh 💙🥳😊

[@infodiff]

Nice lecture/..

[@ThePhenomenals]

Thank You Very Much

[@yadagirimbbs1]

Thank you🙏 madam❤

[@phorphorbnsk8424]

Thank you very much🌈👍🏻

[@muazzama8687]

Can't thank enough 💙

[@asherbarkany]

Thank you so much!

[@sepidehrafii7369]

Thank you !

[@normanlabat5335]

I don't need an explanation. I need treatment. What can I do to elevate my anion gap? The range is 8 to 13. Mine is 7 low. How do I elevate it to 8 or more?

[@alejandroibarra55]

This is gold

[@cauefaquimcosta2339]

Tks from Brazil

[@Doctor-x-8]

Explanation 🔥

[@Muhamm4d_MD]

thanks alot

[@VitorExpedito]

Perfect.

[@yashvardhansharma999]

Thanx meam

[@cloudwalker7001]

Nice👍🏻

[@iruri4u]

Thank you

[@stellajaames9116]

Awesome

[@Srmp347]

Awesome simplification.thank you

[@riteshchaurasia4953]

Nice

[@ojpublicacoes]

Excelent

[@arshithgowda8728]

U did well

[@Drstar-rg9wp]

Greeeeeeeeaaat😭😩❤❤❤❤❤❤

[@sadhanasekar864]

Wow❤❤❤❤

[@sidmehran902]

Respect 🫡

[@davidstojanov8055]

the best

[@woundedblood]

🎉

[@akankshajaiswal7477]

👍👍👍👍👍👍👍👍👍

[@Suma-y9l]

❤

[@rohitgahlawat1231]

Made easy

[@DogHonest]

i love you.