Antibiotics - Mechanisms of Action (Classification) and Antibiotic Resistance

Hey Friends,
Antibiotics are a specific type of medicine directed against bacteria. Penicillin was the first available antibiotic on the market. There are multiple antibiotics such as Beta Lactams, Tetracycline or Rifamycin. All have different mechanisms of action. The overuse of antibiotics can promote mutations in the bacterial genome. When the mutation alters the protein structure of one of the antibiotic targets (enzymes e.g. Transpeptidase) by chance this can lead to antibiotic resistance. Multiresistent germs are extremely dangerous and we have to find new antibiotics to prevent to fight them but also be more responsible with the antibiotics we have!
Best
Henrik
References:
Good videos for medicine students:
• Antibiotics: Cell Wall...
• Antibiotic Classes in ...
Papers and Reviews:
aac.asm.org/content/64/3/e012...
www.intechopen.com/books/anti...
pubmed.ncbi.nlm.nih.gov/29109...
pubmed.ncbi.nlm.nih.gov/23489...
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Chapters:
0:00 What are antibiotics?
1:57 MoA: Inhibition of Cell Wall Synthesis
3:17 MoA: Inhibition of Protein Synthesis
4:42 MoA: Inhibition of Nucleic Acid Synthesis
5:24 Wonder Drugs?
5:48 Antibiotic Resistance

[@earth2k66]

Bacteria: What doesn't kill me, makes me stronger. Bacteriophage: Nah, I'd win. 🗿

[@sachingswamy3187]

That's an amazing and simplistic explanation of the action of antibiotics and mainly #antibioticreistance

[@mariasanchezmenjivar8432]

¡Gracias! Excellent video, a hug from Honduras...

[@genevieveemefaasare8352]

Great master piece . thanks a lot for sharing

[@hannashanavas8074]

Thank you so much. Explained very well👏👏

[@bionicallychallenged7290]

Thank you for that! Your videos have aided me in my writing. I've used your channel to start my research in a lot of areas regarding biopsychology. Thank you for your time!

[@henrikslab]

Thank YOU and you´re welcome!

[@simonidimitriadou7224]

This is so helpful for my medical microbiology exam

[@henrikslab]

appreciate it!

[@suedolma7768]

SO CLEAR. thank you

[@caaanelli4307]

Very helpful video!

[@austinouda1886]

wow such a strong explanation\

[@afsaneemami580]

Thank you it was very useful. 🌼

[@Isabelangler]

Great video my friend

[@ChanTap-dp6tj]

Thank you, you teaching good, continue

[@rosaamaldonado5760]

Excellent video

[@madelineanabella6400]

I have never taken an antibiotic . I’ve always used superfoods etc to boost my immune system. Im sure I will need antibiotics at some point. It’s important to boost your immune system by eating as natural as possible, exercise and sleep ( not over sleep though unless you r sick. This has kept me from getting sick or if I am sick, it’s not long. I also take a multivitamin every day. My mom was a vitamin believer and always gave us a multivitamin every day. My brothers and parents were pretty healthy . I am blessed and hopefully can help other people with this info. I believe in antibiotics if they r needed. Bacteria infections r no joke.

[@iishyxvietxboyii1]

You’ve never had a bacterial infection after a cold or flu? I’m on Amoxicillin right now, lol.

[@Asuthoshi]

Excellent 👍

[@exildahkapasa8051]

Thank you so much ,it really helped😊

[@mominjaved7616]

Alhm du lillahh.. Allahh has given a very good explanation method👍👍👍👍

[@edukee]

Allah has given nothing at all, I am a native Arabic speaker, was taught everything about Islam in school, forced to read the whole quran and ahadith, everything said about human body in Islam is outright wrong. stop taking credit from people's hard work with bullshit.

[@meryemk.8344]

@@edukee 👏🏼

[@amandaallen1898]

Good overall explanation, however please may I suggest an edit. Antibiotics make bacteria unstable not instable. This is the action that kills or severely disrupts bacterial proliferation.

[@henrikslab]

"unstable" might be a better term here, I agree!

[@frenny9903]

good explaination

[@Doraemon-mh2lk]

Thank youuu! 🤍🇳🇵

[@RizwanKhan-co5ni]

Very good🎉

[@abujafar7092]

Thank you so much❤

[@user-kr8dp4ji9r]

Very nice

[@satyabratasvlog]

VERY NICE

[@jujum849]

thank you!

[@mominjaved7616]

Kindlyy make more n more vdeos on biotech

[@pitkamatka]

Great video! 💯 I'm just wondering whether cell wall synthesis disrupting antibiotics work on gram negative bacteria which have another layer of protection outside their cell wall. Also do you know, how do bacteria take up antibiotics that target their protein synthesis? 🤔

[@madelineanabella6400]

That’s what I’m wondering also. They say by 2050 if there r not advancements 10 million people will die a year from infection because bacteria 🦠 has evolved to get past antibiotics.

[@mominjaved7616]

I like ur videossss soooo mchhhh

[@mohammedal-hammadi5085]

Thank you

[@venkybly]

Tq for the info

[@arkaprabhabhattacharya2517]

You and “synthesis” Benedict Cumberbatch and “penguins” People and “Benedict Cumberbatch”

[@zera2314]

It's interesting how you pronounce synthesize perfectly, yet you pronounce synthesis as "thinthethis".

[@virtue1495]

😂😂😂

[@daymarelc869]

Exactly

[@barrowfull-qs2dk]

Interesting how a ww2 wonder drug might produce the fabled super germ in man

[@olga9555]

This voice is computer generated. Early version probably, not perfect

[@zera2314]

@@olga9555 what? haha no it's not

[@user-sk5wq5gc3b]

great

[@hakikamwambene7815]

Thank u

[@phillemonjeremia8296]

Which antibiotic is more stronger?

[@henrikslab]

depends on so many things... e.g. the bacterial strain

[@phillemonjeremia8296]

@@henrikslab which can cure syphilis within 2 months

[@henrikslab]

@@phillemonjeremia8296 www.cdc.gov/std/syphilis/treatment.htm

[@tarlinsaini7650]

SYNTHESIS

[@dott.yaacoubandergassenaqu3623]

#MedicalsystemImmanentrequest #PhilosophyorPoliticsMistakes

[@abdussamad5617]

Yra Der takra ye kho ungriz ye sa ba awayo

[@abuturab3989]

If antibiotic does not work against viruses why doctor prescribe it for viral fever

[@henrikslab]

www.healthline.com/health/viral-fever#treatment This is very likely wrong of the doctor. If at all, viral fever should be treated in severe cases with antivirals (e.g. Tamiflu). Antibiotics should not be prescribed in case there is no bacterial infection.

[@sakalarichard784]

👊👊👊👊👊👍👍👍👍💪💪💪💪💪

[@MedicalBroadcast]

Please be careful with antibiotics use.

[@anitachavan1507]

It was 1929 not 1928

[@henrikslab]

My sources say 1928: www.sciencemuseum.org.uk/objects-and-stories/how-was-penicillin-developed www.history.com/this-day-in-history/penicillin-discovered

[@minhhunglam5347]

Hi

[@Rom.z]

جسق

[@minhhunglam5347]

Help me

[@nilo5016]

Dieser deutsche Akzent 😂

[@minhhunglam5347]

Help me