Patient with lupus has a higher chance of developing APS, you should suggest a mixing study ie dRVVT assay prolong drvvt + normal plasma if corrrected -factor deficiency and if not corrected then suggest a presence of lupus. Confirmatory test followup adding excess phopholipd clotting should normalize.
@eruiluvatar4526 Жыл бұрын
I'm sorry I still don't get it. So the antibodies target and attack the phospholipids, which are fat acids that bind on the the coagulant factors (on the cell membranes). Due to these attacks the patient's physiological ability to perform a normal haemostasis is interrupted, disturbed. So how does a thrombosis occur? Is it because the cell membrane is attacked, which leads to cell lysis whereafter an accumulation of the cell materials? Update: after a little digging; so the thrombosis occurs because the antibodies do attack but also promote the epithelial cells, thrombocytes and WBC to form a clot. Correct? So they damage but promote?
@barathvenkateshr4494Күн бұрын
Now u got it?
@beniamino77334 жыл бұрын
thank you very much. it was very helpful to me.
@Learningin104 жыл бұрын
It's our pleasure, we're glad you liked it! Subscribe to us to keep in touch and visit www.learningin10.com to know more about us! Best regards, Learning in 10
@promamushreki42635 жыл бұрын
spellbound! very nice. I think you can add about other treatment modalities such as eculizumab in refractory case/ aPL nephropathy, immunomodulator in autoimmune hemolytic anaemia/ thrombocytopenia.
@kasahunbentimerga3006 Жыл бұрын
Nice presentation
@tysonchickennugget Жыл бұрын
how likley would it be when tested the 2nd time ,when the first test was high
@nakayestella-tb7lq Жыл бұрын
Thank you
@Nebatnani-dh3ku Жыл бұрын
Crystal clear 👌
@angadsingh57763 жыл бұрын
Nice video
@Rina.136 Жыл бұрын
To the point!
@tubeysr2 жыл бұрын
Why does thrombosis occur if there is a defect in anti coagulation (anti phospholipid)?
@helloagain14002 жыл бұрын
Anti coagulation factors are the prinple of measuring how much the blood coagulate Just like gas in the car without it wont move
@dr.bramantyonugraha30342 жыл бұрын
Thank You. So helpful.
@SoShyMeka4 жыл бұрын
Beta-2 Glycoprotein I Ab, IgG
@zachariahsmith91303 жыл бұрын
Not much honestly. You need other labs to correlate
@patient38413 жыл бұрын
Thx
@Natureboy_23 Жыл бұрын
I was diagnosed with lupus anticoagulant im a 28 year old male i dont have lupus this came out of nowhere i had dvt and pe and idk wat to do i feel lost and defeated at times
@ljhendrickson29607 ай бұрын
Have you seen a hematologist or a rheumatologist? Best place to start. God bless.
@r.i.a64854 жыл бұрын
Thanks a lot
@Learningin104 жыл бұрын
It's our pleasure, we're glad you liked it! Subscribe to us to keep in touch and visit www.learningin10.com to know more about us! Best regards, Learning in 10
@EAGLE-yf5bf4 жыл бұрын
Thanks alot mam!
@salammohammed65432 жыл бұрын
Thank U
@thomasserge73593 жыл бұрын
What causes coagulation disorders in the presence of the antiphospholipid antibody syndrome?
@jenniferfrances87933 жыл бұрын
Johnson and Johnson vaccine
@stefanshen16223 жыл бұрын
@@jenniferfrances8793 F. Lol
@anomalyp85842 жыл бұрын
coagulation can happen spontaneously, but triggers like infection or inflammation, trauma, immobilisation,... are the most common findings in trombosis events.
@sabe18407 ай бұрын
❤❤
@azieziera65962 жыл бұрын
Is there any way to cure APS?
@Wildewhitley2 жыл бұрын
I have APS, suffered these "treatments" for 34 years, and finally learned it was all coming from food! 5 months ago I went to a 100% organic diet, and am seeing more progress in that time, than I have in my entire life! I'm talking all around health people! It's all improving.....It's diet! Diet!!!! I tell you!!!!!!
@tubeysr2 жыл бұрын
Let us know after a year how you feel.
@chestnutmair1 Жыл бұрын
I have started Mediterranean diet. I am hoping this will help
@jonathanstempleton7864 Жыл бұрын
"It's made from people!" How you getting on?
@jonathanstempleton7864 Жыл бұрын
@@chestnutmair1 Is that pizza?
@Wildewhitley Жыл бұрын
@@jonathanstempleton7864 not sure your asking me but I'm getting along great! Diet has completely changed my life in every way!