Breaking Down Biotech Innovations with Dr. Bob Langer

Today’s guest is MIT professor, chemical engineer, scientist, inventor, and investor Dr. Bob Langer. Dr. Langer has over 1,400 granted or pending patents and has been cited 374,000 times (and counting)! As a co-founder of Moderna, he has great insights into the potential of mRNA to treat diseases of various descriptions. Joining us to pick this extraordinary mind is clinically trained entrepreneur, Dr. Charlie Roberts. In this conversation, we discuss emerging biotechnologies, the potential of artificial intelligence (AI) in this space, as well as what might be attributed to the current downturn of the market. Dr. Langer lists potential time-to-market accelerators for new therapies and vaccines and shares his advice for those looking to make an impact from an academic and/or entrepreneurial standpoint. Tune in to hear more about the innovations Dr. Langer has been involved in over the years, and what we can look forward to in the future!
Key Points From This Episode:
- Dr. Bob Langer highlights his favorite patent.
- Dr. Langer’s career achievements.
- Some factors impacting the current biotech market downturn.
- The correlation between magic and science.
- What mRNA is and why it’s an ideal candidate for treating disease.
- The personalized cancer vaccines Merck and Moderna are currently developing.
- Under what circumstances mRNA isn’t the solution.
- The emerging biotechnologies Dr. Langer is most excited about.
- The applications of organs on a chip.
- The potential of AI in the biotech space.
- Potential time-to-market accelerators for new therapies and vaccines.
- How to make an impact in the academic and entrepreneurial biotech spaces.
- The importance of understanding intellectual property.
- The team aspect of innovation.
- Dr. Langer’s tales of perseverance.
- Strategies for enforcing IPs.
- Dr. Langer’s delivery expertise.
- How he’s balanced his work and family life over the years.
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[@cbmusgrave]

Bob is an absolute legend - his academic, innovation and entrepreneurship accomplishments are phenomenal - and he is a really nice guy!

[@bufnyfan1]

He's a CROOK. He teamed up with a charlatan named Frank Reynolds to found a company called "In Vivo Therapeutics" to advance a polymer device for spinal cord injury. Reynolds used investor money from In Vivo as his own private "piggy bank". He used company funds for limousine service, Broadway shows and strip clubs. Langer was on the scientific advisory committe of this company and did NOTHING to stop him until the rest of the board stepped in and ousted Reynolds. Then Langer helped Reynolds to found another sham company (PixarBio) for a pain release device. Ultimately Reynolds was convicted of securities fraud and sentenced to 7 years in prison. (he died in prison in January 2022). Reynolds was told to pay back all the investors $7.5 million he swindled and it's doubtful anyone will get anything back. Langer helped Reynolds with a very slick promotional video (look up "Frank's Story PixarBio on KZbin) and Langer is front and center in many of the promotions for this company. Ultimately Langer just "washed his hands" of this whole thing without a thought to many of us who trusted him. I don't care if he wins a "Nobel Prize" for anything else he does---his association with this fiasco has tainted my view of him forever. And Langer's "wonderful" polymer scaffold for spinal cord injury recently failed miserably in studies---I'm sad for the patients--but couldn't care less about him and his "prestige"

[@dirkiify]

Perfect sound

[@user-ye5di3nd4u]

No sound

[@mr_digdeeper]

Which ark etf is exposed to bio tech?

[@RA-qb4gl]

Geonomics ARKG

[@thegodhead]

@@RA-qb4gl ARKK, as well

[@heinzyketchupy4175]

Y’all’s TUSIMPLE call is turning out to be a disaster