Bilirubin Metabolism - unconjugated and conjugated bilirubin

  Рет қаралды 226,938

Armando Hasudungan

Armando Hasudungan

2 жыл бұрын

"Bilirubin is formed by breakdown of heme present in hemoglobin. RBC contain many haemoglobin molecules which are broken down to heme and globin. Heme is further broken down by two enzymes; heme oxygenase followed by biliverdin reductase forming bilirubin and iron.
The bilirubin formed is unconjugated and is lipid soluble. It binds to albumin which acts as a transport protein. The albumin-bilirubin complex circulates around enters the liver system and dissociates.
Here they undergo what is called glucuronidation. This process makes substances such as Bilirbuin more water soluble which allows it to be excreted in bile and urine. It is secreted into the biliary system and is a component of bile."
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Пікірлер: 55
@VeraLawRN
@VeraLawRN 2 жыл бұрын
I watch a lot of older videos. It’s very cool to see his progression with the art program used. Much appreciated.
@fatemazehera5424
@fatemazehera5424 Жыл бұрын
For once, I ACTUALLY understood this concept of bilirubin 😭😭👍🏻👍🏻
@priyanshupati7670
@priyanshupati7670 2 жыл бұрын
These videos provide better explanation with perfect diagrams.
@shahzaibihsan3259
@shahzaibihsan3259 2 жыл бұрын
thanks! very concise explanation
@drvkphysiologyclasses
@drvkphysiologyclasses 2 жыл бұрын
Concise n nice explaination..
@marvellover3689
@marvellover3689 Жыл бұрын
Woooooooó .. greater.........I can never imagined...this will be that simple.....
@leonardoretureta2627
@leonardoretureta2627 2 жыл бұрын
You are the best!
@adriomario8588
@adriomario8588 2 жыл бұрын
Very informative video
@MbabaziJackline-md5fn
@MbabaziJackline-md5fn 20 күн бұрын
Much love ...these videos have ril helped us so much.God bless u with more more knowledge
@miaclairecatapang5168
@miaclairecatapang5168 Жыл бұрын
life saver! tysm! 👏
@YaserZahin-tw7yo
@YaserZahin-tw7yo 9 ай бұрын
Thank you very much, it is very understandable.
@user-ko6zq2cl5f
@user-ko6zq2cl5f 4 ай бұрын
the video is great, thank you
@riyastories2504
@riyastories2504 Жыл бұрын
😍wow... So good
@shesadiamond5167
@shesadiamond5167 3 ай бұрын
Thank you !!
@theultimateguideofhumanbod186
@theultimateguideofhumanbod186 2 жыл бұрын
Bestttt👍
@hassanhussein137
@hassanhussein137 3 ай бұрын
Nice video
@samannazeer227
@samannazeer227 2 жыл бұрын
Hi! Great video. I need your help, I'm doing research on endometrosis. I'm Bioinformatics student. I need endometriotic patients data with history of recurrence of endometriotic ovarian cysts. From which database or site I can download data?
@aaqibmohiuddin5589
@aaqibmohiuddin5589 Жыл бұрын
helpful, tysm
@Ilovehobiii
@Ilovehobiii 2 жыл бұрын
thank u🙏🙏
@askndr3985
@askndr3985 2 жыл бұрын
Where i found Explanation of the first year subjects in medicine؟🌹
@nihalsinghrajput2085
@nihalsinghrajput2085 Жыл бұрын
Thanx sir
@cynthiakeimy649
@cynthiakeimy649 Жыл бұрын
Dope
@medicinerecap5303
@medicinerecap5303 2 жыл бұрын
Kindly make a lecture on mastocytosis
@user-ut7bx3lg9t
@user-ut7bx3lg9t Ай бұрын
I love u sir u r great love from india💞
@essaamer7702
@essaamer7702 Жыл бұрын
بالعراقي ،، عاشت ايدك In arabic iraqi accent means: great job 👏
@juhah
@juhah Жыл бұрын
we know all this hoccus poccus but we cannot cure cancer?
@tahirariaz8506
@tahirariaz8506 Жыл бұрын
Hi, great video. Would you mind telling me which app you are using for the lec. Would be grateful. Thanks
@janetmaina9903
@janetmaina9903 Жыл бұрын
Wow!
@bishakha155
@bishakha155 9 ай бұрын
Thanks I have my exam tomorrow❤❤
@shoshannadzav7451
@shoshannadzav7451 2 жыл бұрын
Im following you! Can you go over DM meds, please?
@armandohasudungan
@armandohasudungan 2 жыл бұрын
Yep will create something on this again soon
@lorenrenee1
@lorenrenee1 2 жыл бұрын
The cells of an organ are all geniuses at what their jobs are.
@kajalrai7966
@kajalrai7966 Жыл бұрын
👌👌👌
@Nushka23
@Nushka23 Жыл бұрын
Can high direct bilirubin, but normal liver function, still be a sign of something sinister?
@certifiedcars3970
@certifiedcars3970 10 ай бұрын
Waiting for a response to your question also😢
@lavas2023
@lavas2023 6 ай бұрын
Can u tell me please what is the ‎
@mariecrisgono3730
@mariecrisgono3730 2 жыл бұрын
💖
@arsalanzaidi15
@arsalanzaidi15 Ай бұрын
if cb is hydrophilic can't absorb by intestinal mucosa then why urobilinogen absorbed?
@ambitioushustla
@ambitioushustla Ай бұрын
For someone that's been cured of hepatitis b and the skin remained yellow for years even though I have been discharged by my speclist. What do you recommend to darken my skin. I'm a black person
@tharukaharischandra7877
@tharukaharischandra7877 9 ай бұрын
🙏
@Emanaia
@Emanaia Ай бұрын
@mgoddette1
@mgoddette1 7 ай бұрын
Makes me wonder about cats
@clashgamer4207
@clashgamer4207 2 жыл бұрын
I literally just took an exam about this 😭
@quonitx1140
@quonitx1140 Жыл бұрын
I know ryt 😂
@josephmburu2236
@josephmburu2236 Жыл бұрын
😂😂
@Cooper407
@Cooper407 Жыл бұрын
Did you pass
@clashgamer4207
@clashgamer4207 Жыл бұрын
@@Cooper407 I got a 59% in that module which was my lowest 😔
@Cooper407
@Cooper407 Жыл бұрын
Are you Indian? What are you studying now?
@sakshikohli5393
@sakshikohli5393 Жыл бұрын
Why is conjugated bilirubin high in biliary atresia?
@neverendingfootsteps1543
@neverendingfootsteps1543 8 сағат бұрын
Conjugated bilirubin produced in liver can't get out of the liver to the bile due to obstruction , and hence gets spilled back in circulation . Spilled back means effluxed out of the cells from where it was produced and gets into the hepatic blood vessels within the sinusoids. Just not in the bile duct where it should go through
@salmanmalik7282
@salmanmalik7282 2 жыл бұрын
Hello I have by birth billrobin i am 29 years old
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