Autism: A view from neuroscience - A CCN public lecture

Given by Dr. Caroline Robertson of the Dartmouth Autism Research Initiative, in the Department of Psychological and Brain Sciences.
Sponsored by: Center for Cognitive Neuroscience at Dartmouth
Recorded October 18, 2018

[@nataliefoxmartin9764]

We also need better assessments for neurotypical passing children and adults. I slipped through the cracks until I discovered ASD myself through research and sought out a diagnosis as a 29 year old. And at first I was misdiagnosed with BPD and Bipolar II and I had to record my own traits and experiences for two years before I went back and got correctly diagnosed. This women is INCREDIBLE, I will be looking into more of her work.

[@wickjezek1101]

Sadly this is so common. I got diagnosed with BPD and depression originally. My son was diagnosed with ADHD at 5. It took until he was 13 to get the autism diagnosis. After going through the evaluation with him I sought out a neuropsychiatric evaluation for myself. At 30 - I got my autism and ADHD diagnosis as well. I think in AFAB people the overstimulation, meltdowns, and idiosyncracies are read as emotional disturbance rather than a neurodevelopmental difference.

[@superstar5123]

if you had to receive multiple diagnoses until you received the one you "wanted".....

[@KatherineVVE]

I had the same but I refused to take diagnosis. Too much for DSM V definitions and now it is spectrum. I don’t have severe impairment, so I don’t need anything else but working on myself and be happy.

[@annak29]

Astrocytes & glial cells are responsible for the development of neurons & synapses. They are also immunomodulatory! Interesting how immune system function is not discussed in the autism-sphere...look who funds the funders and you will know why!

[@annak29]

You can have blood testing for immunoglobulin reactivity to foods. Commonly dairy, sulpha, nut proteins, but also salicylates in fruit remain toxic in the body due to lacking enzymes to break down in the gut. Part of the genetic differences.

[@kareeseboone6011]

Study the Adults that were missed during childhood!! It makes no sense to me to put all your effort in new developing brains when you could study the connections .. Markers .. and commonality's in adults who can COMMUNICATE for the youth who can't! If there truly is common markers and patterns they will be fully developed in adults and identifiable.. Which will also allow for better services all around

[@kareeseboone6011]

@@GeneralSocietyInc To me its common sense.. If the medical community really wanted to make a difference they would. But its all about $$ .. I lost faith in them long time ago

[@Breakthebinarybby]

I would wager that it has more to do with the brain development. As you grow your brain changes. If you can capture the brain information closer to the age of development for a developmental condition then the data would be more accurate. The adult brain would serve as comparative but I think the youth brain is very important as well to understand the core. I’d love to capture my brain and be part of a study but I know from childhood to now many factors have contributed to changes that would have to be factored into a study. Like exclusions and all that. I could be wrong but that’s my hypothesis on the matter

[@irish_deconstruction]

Yes, but one of their goals is to try and see if they can diagnose children with autism earlier than the age of 4.

[@irish_deconstruction]

@@kareeseboone6011 How do you know the medical community cares about nothing _but_ money? You don't know that, and if you say otherwise you are dishonest, because you cannot possibly know the collective intent of the medical science community.

[@josephinejeffery]

@@LyricsAndDistortionthis! I agree with everything you’ve said. I feel like I don’t know who I am anymore, what is my trauma and what is my autism since I’m being diagnosed at 48. It’s a huge existential crisis 😅

[@librarian1701-D]

To clarify (from 8:46), from my research, yes we 'may' all have some degree of autistic traits, but we are not all on the spectrum. Neurotypicals are not on the spectrum/ASD. I am female in my fifties w/ASD...just recently discovered...also diagnosed w/other disorders that I always knew were not true (as so many females have). Anyway I sometimes feel upset when a neurotypical says we're all somewhere on the spectrum, because I feel like they don't understand and trying to write it off, ignore my needs etc instead of understanding there is a neurological difference in how i am in the world. It is isolating tbh, because it says they don't want to see me. I suppose from what she is saying 'above a certain threshold' lies the difference, but caution should be held in this kind of statement.

[@juliahart8593]

"We're all autistic!" "Autism has a prevalence of 1 in 59" which is it lady

[@murielbilly4296]

It makes me upset too. I don't feel understood. Some ' 'autistic' traits in neurotypicals are very far away from how we, neurodivergents, are struggling on a daily basis. How could a specialist believe it? I'm a woman diagnosed at 39. I'm 55 and I 'm very upset.

[@marthamurphy3913]

I was recently diagnosed as autistic at age 75. The way I look at the brain differences is: Every single individual human has differences in brain structure. Autism diagnosis is somewhat subjective. Each autistic person has a different profile (spectrum) of symptoms. For example, I have relatively few sensory issues. As long as we don't have any "hard data" determinants of autism, how can we know people we think of as neurotypical are not "on the spectrum"? For 75 years, nobody that I know of (including myself) thought of me as autistic. It's only in retrospect that I can say, "Oh, yeah. That was probably because of autism." The psychologist who did my diagnosis said she had to get agreement between several of the psychologists in her agency to diagnose me as autistic. It wasn't until I shared my results on the "Reading the Mind in the Eyes Test (RMET), which I had taken online, that she was sure I am autistic. Social interaction is the worst part of autism for me, and yet I making eye contact is not a big part of my problem.

[@abelquinones3646]

This lecture was very interesting. I have autism and I've been looking into it from a microscopic deep scientific point of view. (Science is my favorite subject). What I enjoyed about the video was when you went into the neurons in the brain at 18:00. The beginning was also very interesting when Dr. Robertson stated that there is no core to the diagnosis of Autism at 5:45 and how it touches all parts of sensory in human behavior at 6:15. Thank you Dr. Robertson for this lecture.

[@annak29]

Please read research in "neuroimmunology" and "psychoneuroimmunology", yes, these are research areas very fruitful for autism related disorders. Astrocytes & glial cells are responsible for the development of neurons & synapses. They are also immunomodulatory! Interesting how immune system function is not discussed in the autism-sphere...look who funds the funders and you will know why!

[@micheletaylor3941]

​@@annak29is it autism speaks, who funds this study?

[@4fgs34]

​@@annak29who is funding the funders?

[@photoniccannon2117]

This is one of the best summaries on this topic I've ever seen. I've been researching this for a while. This video is spot on and encapsulates much of what literally required me to read HUNDREDS of studies to learn (there is a lot of conflicting information out there, many researchers are struggling to grapple with how unique different autistic brains are from each other. This video addresses this and hits the nail on the head.)

[@annak29]

Please read research in "neuroimmunology" and "psychoneuroimmunology", yes, these are research areas very fruitful for autism related disorders. Astrocytes & glial cells are responsible for the development of neurons & synapses. They are also immunomodulatory! Interesting how immune system function is not discussed in the autism-sphere...look who funds the funders and you will know why!

[@liamdc1227]

what do you mean by this@@annak29

[@watchingthebees]

I’m autistic and I love how inclusive this is. Thank you for making it sensory friendly and including autistic people, I know it should be common sense but it really isn’t. I really appreciate it 😊

[@creeddax5132]

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[@kamryncoen1534]

@Creed Dax instablaster :)

[@creeddax5132]

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[@creeddax5132]

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[@kamryncoen1534]

@Creed Dax No problem =)

[@richiepropster4313]

There are various behavioral symptoms that can be spotted as early as day one. For instance, a lack of eye contact and emotional response can be seen extremely early. However, there are cases in which autism develops seemingly sporadically at some point in early life. Each case is different. Often, individuals are not diagnosed for various reasons. Sometimes, diagnosis can be curtailed due to familial dynamics or a lack of resources. Other times, diagnosis is not able to be made due to coping mechanisms and the wide display of symptoms. The history of autism will explain it as a male disorder. Yet, there is reason to believe that the differences in how we raise young males and females and perceive the male or female role can exhibit different expressions of autism. This brings the possibility that we are diagnosing not the true disorder but it's expression in accordance to a lack of social skills support.

[@scarletsletter4466]

Females are socialized differently and ASD (& ADHD, learning disorders, & even some mood disorders) are less likely to be diagnosed in females. The reality is that parents exhibit greater concern about certain ASD behaviors exhibited by a son. For example, a son is far more likely than a daughter to be taken to the pediatrician if he has emotional outbursts & fails to engage in school activities/ lessons. The daughter is more likely to be characterized as "dramatic," "sensitive" & a "daydreamer."

[@jlllx]

normal human behaviors relabeled as autism.

[@charlyheather1822]

I've been trying to learn about the neuroscience of autism for a while now, and until now every talk I found was very ... invalidating and patronizing towards the autistic community, so I am very glad to have found this speech and this research initiative. I would totally volunteer as a research subject as well, but I live nowhere near the USA, so ... Thank you for the awesome presentation of information!

[@lanceg3208]

Thank you for this, Caroline

[@bertinii]

Excellent presentation!Looking forward for future research on this topic by you guys.

[@diegos.8705]

Awesome presentation. Great job, thanks for sharing

[@RoseA.Dewine]

Very helpful to be able to visualize these differences! Thank you!

[@leam6371]

Loved this! Thank you!

[@menosproblemos6993]

Got atypical autism and an interest for neuroscience. This was awesome! Splendid! WELL done! 😄 And THANK YOU

[@NoahLoftier]

Autisitic person here! I've always been fascinated by psychology and its direct connection with neuroscience. Thanks for this presentation! We greatly don't understand a lot of stuff in our brains, humans in general, of course, and every connection neuroscience has to do with a lot of other fields, such as physics, philosophy and conciousness, chemistry, etc.. I find that inspiring.

[@RohitPant04]

Well presented. I am impressed by the work that Dr. Robertson has presented here and also by the work that she has carried out. Autism is a really bright field for every budding Neuroscientist out there!

[@annak29]

It's a new industry for "big pharma", created by them. Look into glyphosate teratogenic and multigenerational genetic effects. Please read research in "neuroimmunology" and "psychoneuroimmunology", yes, these are research areas very fruitful for autism related disorders. Astrocytes & glial cells are responsible for the development of neurons & synapses. They are also immunomodulatory! Interesting how immune system function is not discussed in the autism-sphere...look who funds the funders and you will know why!

[@ammogan]

I have a solution to your misunderstanding problem. Have people with Asd study people with Asd. Allistics will never understand us. We are alien to you. Please include us, not only as subjects but as researchers. Very many of us are highly intellegent and would make major breakthroughs in these studies.

[@nowie4007]

That actually is a good proposal tbh

[@f.u.c8308]

Great point. Check out the Monotropism theory of autism if you haven't already. It was created by autistic people.

[@charithadissanayake3304]

Love her ♥️

[@rutharunasalam1349]

brilliant

[@neoncatmedia]

Gret talk - I'd love to watch something this good about ADHD as someone with ADHD

[@bjorntheviking6745]

This feels like Eugenics to me.. she stated that they want to diagnose early in life, which clinically generally means in utero. I am level 1 borderline 2 autistic, I have a PhD and have assisted in my chosen field to further science, but I could have just been an abortion, I am the face of autism as are many others born with this..

[@ADHDologia]

Same, I'm autistic with a PhD, too. I cringed every time she said "with autism" instead of "autistic". The work is valid but the framing of it reflects Simon Baron-Cohen's ableist take on autism - and I believe it's no coincidence, as she studied under him as stated in the beginning of this recording.

[@Nour_missaoui]

Very helpful. Thank you❤

[@towzone]

It's not a disorder, it's a state of being that gives humanity a chance to advance, despite the inability of typicals to have original thoughts. When we were raised by the village, there was the ability to format our autistic brains to be useful to the situations present in the village. Today, a child's job is to be a child raised in a bubble with inadequate stimulation and opportunities to build a useful autistic condition. Without proper opportunities the autistic brain can go haywire very early in life.

[@kimyuwurandom]

I was diagnosed with autism last year (I'm 29 years old) and since I started suspecting I was autistic, I've been more interested in learning about it (it always caught my attention, but from the last 3 or 4 years that curiosity has been increasing exponentially). The foundings she exposed are fascinating! I would love to participate in DARI studies, testing, or anything they may need for research, but I'm from Chile 😢 I would love to see you expanding

[@prismaticspace4566]

Very interesting introduction, makes me curious about Autism again.

[@emilyf.170]

Thank you so much for sharing! Having studies illustrated where a layperson may be able to understand them is very meaningful.

[@josephmartin1540]

Bravo!

[@nataliefoxmartin9764]

OK, right off the bat, can I just say… Starting her lecture by letting everybody know that it was sensory friendly? QUEEN. Literal QUEEN.

[@lindaclairesartori]

What the f... does that mean?? "QUEEN. Literal QUEEN." what????

[@nataliefoxmartin9764]

@@lindaclairesartori it means that she is awesome for starting the lecture off by letting people know that it’s sensory friendly, what the “f” do you think it means? Clearly this woman who studies autism is aware of autistic peoples’ needs and that’s extremely encouraging because many researchers and educators aren’t. It’s just really nice to see as an autistic person with sensory issues.

[@jonaskoelker]

@@nataliefoxmartin9764 Maybe Linda Sartori tends to take things literally and thus needed an explanation?

[@coldlogic800]

No female is a queen just like no man is a king. I did strongly appreciate her concern

[@coldlogic800]

Just do not engage in SIMP or ego inflative behavior. If she is competent or consider it call it for what it is. Conflating your admiration to the irrational does no good.

[@michaeltownsend429]

I’m a bit lost about something here. At 22:13 there is mention of drug therapy. Why would drug therapy be an aim? I love being Autistic. I wouldn’t change me at all. I don’t suffer by being Autistic. I do suffer because of other humans whose concept of normal isn’t expanded enough to include atypical, natural (and hence normal) variance in human thinking, perceiving, relating and learning - but that’s a function of their choice, which is frequently a function of what they have been taught, which is frequently a function of peer pressure from dead people. That’s vastly less of an entitlement than my entitlement to be my authentic, natural, very normal and colourfully atypical self. Don’t forget that difference is variance around a norm - we are very f***ing talented at many things too, and that continues to be a great asset to our societies. You can keep your therapies thanks. I’m good.

[@Moving_Forward247]

Fascinating. I pray there can be interventions esp for non verbal patients. There is indeed a HUGE spectrum-we should sub classify ASD more to make the research more meaningful.

[@wickjezek1101]

I have thought this myself. I know we have level 1, 2,& 3 but I don't think that really expresses the full spectrum. Especially since removing the aspergers diagnosis in DSM-V. I don't know what features would warrant categorization, but that's for the scientists to figure out.

[@foljs5858]

@@wickjezek1101 Yeah, removing the Aspergers diagnosis only serve to make the distinction more fuzzy, rather than more illuminating

[@magda_plays]

I have been diagnosed with Asperger’s Syndrome and I wholeheartedly agree. It should absolutely have stayed subdivided, current classification makes zero sense to me.

[@RobDeManc]

Can we not say that autism is a disorder in social development caused by sensory and communication issues that encourages autistic people to gravitate towards solitary tasks that focus on specific topics? So the issues regarding fixated interests and repetitive behaviours are coping mechanisms for the disorders in social and sensory processing.

[@infinitism576]

This is neat and all, but the thing I never understood is scientists look into the blood and biology of autistic people, but have they ever talked to a autistic person that can speak?

[@bspsych-lectures4091]

Great presentation to make us understanding the ongoing research on Autism

[@cutestkittensanimalrescuep8531]

I'm sure she dumbed down this lecture down for an open audience but the thing is is we'd like to hear what sections of the brain are affected who couldn't she verbalize the sections? I've never heard of neuroscientist say the side of the brain instead of what section of the brain I didn't like it I would have liked to hear exactly the sections that were affected and in what ways.

[@ber9313]

Well she said its not so much the parts so much as the integration between parts of the brain. If parts of the brain aren't communicating she said this is the outcome that leads to trouble with processing all that is coming at us. I know I too was hoping it could be seen like other anomalies but its really complicated.

[@menosproblemos6993]

Seemingly every part of the brain can be affected. I got curious about what the names of the affected parts of the brain where, so I googled 'brain map' and found the names of the corresponding parts she'd shown.. but when she said that the parts affected are different between individuals I just dropped it, and instead checked up gamma-Aminobutyric acid on Wikipedia =)

[@cutestkittensanimalrescuep8531]

@@menosproblemos6993 Thank you.

[@jakewilliams3523]

The big consistency is over active connectivity related to gaba transmission which is meant to inhibit activity. Because gaba function is not optimal the brain doesn’t manage stimuli well leading to many symptoms. In some of the MRIs she showed there also appeared to some connectivity issues in the prefrontal cortex area as well as the temporal lobes. According to this talk the temporal issues seem more uniform based on her findings. Another thing to keep in mind is that if the diagnostic tools (observations and assessments) are of question then you end up with a skewed sample for mri. So the clinical tools need to be really developed to validate the mri data.

[@donniedorko3336]

2:53 I teared up a little bit at this. Bless you

[@HassanSelim0]

Yes, being able to get up and walk around during a lecture, or taking a break and coming back? Where was this when I was in university?! 😢

[@birhanuasmare5468]

How can someone get you in person like me who is in deep love of neuroscience. You are my best ever.

[@johnyardley8317]

Hi, a very interesting lecture. When Dr Robertson mentions problems with filtering it might be that a suitable person with Autism/ Aspergers might be able to use their neuro difference/s to help with this. The autism community struggles with anything that doesn't involve those with Neuro Diverse perspective. Might I recommend you involve those including Temple Grandin, Tony Attwood et al. to contribute. For example, it's very interesting that identifying a paucity of Gaba in the ND brain. However this should be treated with extreme caution with considering future medication development.

[@annak29]

You may be interested in reading about the teratogenic effects of glyphosate, and multigenerational genetic variation. Chemicals are stored in human body fat. A pregnant human has a high percentage of body fat, especially in a generally overweight society. It's a toxic milieu. Please read research in "neuroimmunology" and "psychoneuroimmunology", yes, these are research areas very fruitful for autism related disorders. Astrocytes & glial cells are responsible for the development of neurons & synapses. They are also immunomodulatory! Interesting how immune system function is not discussed in the autism-sphere...look who funds the funders and you will know why!

[@quinnmk1220]

Autism is as much a disability as it's more of a difference. For example, the main "issue" is the struggles with social communication. I personally struggle a lot with this especially in environments that are over stimulating. However, even in those environments I can communicate with others with Autism just fine. Autism is a difference not a disability. The disability only is a reflection of the neurotypical society built that does not accommodate the different needs of those with autism.

[@ExistenceUniversity]

You literally just described a disorder

[@quinnmk1220]

@ExistenceUniversity Yes, but my point is that if those with Autism were the majority and society accommodated their sensitivities and social needs, then Autism would not be really labeled as a disability. Being a neurotypical would be called a disorder because they require social gratification through external factors such as social interactions to learn about others that an Autistic society would not need nearly as much. A disability is not being "able" to do something without assistance because the world does not accommodate their "difference."

[@ExistenceUniversity]

@@quinnmk1220 That's literally the description of a disorder though lol. A dis-order is a struggle to be in order with society. The fact that people have to stop behaving normally to accommodate those with disorders is merely proof that disorders exist as such.

[@YearZeroVids]

I think baclofen is similar to the GABA molecule. If given early on could it slow the overstressing damage caused to other systems?

[@scarletsletter4466]

There are many ways to increase GABA activity, including many sleeping pills, muscle relaxers like Baclofen & even alcohol, but it can lead to addiction & seizures. Baclofen isn't approved for use in children under 12, plus it directly relaxes the nervous system by mimicking GABA so it's habit forming & causes seizures upon cessation. You don't want to use a drug like that in pediatric patients since they're prone to forget a dose & could have a grand mal seizures where they choke on their tongue or drown. I'm a neuro and I consider the consolidation of the DSM category (to ASD instead of the specific diagnoses) to be the worst thing to happen to autism research & treatment. There is a huge difference in severely disabled patients who are non-verbal, sitting in a corner rocking back-and-forth & unable to make eye contact vs intellectually gifted tech execs & engineers whose only challenge is in forming/ maintaining close relationships. That's why her talk is all over the place (& in fairness, the scientific studies show tons of differentiation in ASD brains & among patients with ASD)

[@gavinwaterman5456]

That's interesting about the brain filtering out information, why only focus on the brain, what about the spine and nervous system. We have many different brains in the human body and they always talk about the cerebal one.

[@zjw5]

Synopsis: Everyone's brain is unique. Some people's uniqueness makes it harder to operate in society than others.

[@lizairvine9159]

Dynamic motion is interesting. My kids were diagnosed late, in part, because they are so agile. They are both great at dance and gymnastics, with excellent balance and grace. But faces and people are a bit of a mystery Another reason for the late diagnosis was because Autism is so prevalent in our family, that we didn't notice that anything was wrong because everything they did was normal to us Last point is on your map, there is nothing in Africa. The situation for Autistics in Africa is pretty bad. You will only get a diagnosis and treatment if you are lucky enough to live near a private center for Autism, which are very rare. Treatment is hugely expensive, so most Autistics rely on the internet to treat themselves. Thank you for an interesting speech.

[@lm380]

The lady referred to the visual perception of dynamic motion. This has nothing to do with being agile

[@wickjezek1101]

My son got diagnosed at 13 and I did at 30. My cousin is now going through the evaluation process at 35. Our family never noticed. I don't think anyone else has full-blown autism but they are DEFINITELY in the broader autistic phenotype or BAP. If you have one family member with autism chances are there are 2-3 who fit the BAP criteria if not autism.

[@annak29]

You may be interested in reading about the teratogenic effects of glyphosate, and multigenerational genetic variation. Chicals are stored in human body fat. A pregnant human has a high percentage of body fat, especially in a generally overweight society. It's a toxic milieu. Please read research in "neuroimmunology" and "psychoneuroimmunology", yes, these are research areas very fruitful for autism related disorders. Astrocytes & glial cells are responsible for the development of neurons & synapses. They are also immunomodulatory! Interesting how immune system function is not discussed in the autism-sphere...look who funds the funders and you will know why! (Listen to her grant sponsors listed by the host- scientists are not impartial to their funders).

[@patriciaanndemello4652]

I would guess that depending on what country you live in the Autistic diagnosis would be different depending on social norms. With the exception of non verbal behavior, maybe being socially awkward or displaying little eye contact is not a thing or for that matter, many symptoms associated with the lable of Autism.

[@Nekotaku_TV]

If you follow the DSM-5 it shouldn’t matter but it’s true that countries and clinics do things a bit differently. But the traits you metioned aren’t requiried traits for a diagnosis.

[@timjosling9298]

Very much an outside view and does not see things from ASD perspective. But I appreciate she is trying e.g. the sensory accommodations and the quiet room. Would have appreciated more detail on the technicals - aspies are often highly technical. Also we don't need the blather at the start of these videos.

[@Jorbz150]

Everything is an outside view. Your view is an outside view from another perspective. That's not a meaningful statement.

[@ontheodderside]

Thanks for sharing, interesting research! What strikes me is the ongoing tendency to label 'autism' based on symptoms, even though research indicates that there may be very different brain wirings at play here. I remember reading a book by Ayelet Waldman in which she describes how for the longest time she's been misdiagnosed as bipolar, while in reality, it turned out she was experiencing hormonal disbalance due to her cycle. In our desire to explain, maybe we should stop operating under the assumption that autism is 'a thing'. Then there's the second thing, which is that a great many people who would be labeled by DSM5 standards don't actually perceive that there's anything wrong with them. Sure, they have their struggles (everyone does), but their wiring also helps them accomplish amazing things. The tendency to try and 'diagnose' at a very early age and even develop drugs to influence brain wiring has many pitfalls. It's great if medication is available for those who want it, but otherwise - and I know I'm controversial here - this is akin to looking into medication to alter one's sexual preference or other personality traits.

[@jamesa55]

we can only make theories off of data if you have data that would alow this to change please provide it because right now the neurological factors are quite new and science moves slowly so the symptoms are what we currently have as concrete data.

[@petersteenkamp]

Yes, it is possible to assume that something exists as an underlying cause of external effects (like symptoms). But the existence of that underlying something is not always scientifically validated. The official term for this is reification.

[@CD-qr7ec]

I believe the research showing that monotropic thought is at the 'core' of autism is probably correct as it would explain all the seemingly unrelated aspects of it. (I have an autism diagnosis).

[@f.u.c8308]

Exactly, the Monotropism theory

[@coldlogic800]

What seems obvious to me is that there is a string of genetic code that afects multiple functions in many autistic people. Due to gaba responsiveness my experiences are that neurotypical humans are usually inferior to what I was born with. I have the obsessive traits coupled with a need to be logical. Regular people are just silly. Two points I want to make. We are not necessarily disabled and do not may not need medical correction. Secondly, don't look for a single influence. The pattern of symptoms and biology strongly implicate a group of genetic variants.

[@munireg.dedeoglu3584]

after this video i started to wonder if there is a core pattern for human behavior of people other than the ones that accepted as autistic because as i understand the result of each test varies drastically person to person so it is hard to conclude something certain so maybe it could give some different viewpoint to look at from other way, also to start, if there is a pattern other way at least we can ask why its that certain way

[@ivanaldana1030]

I'm all for research and learning more about the autistic brain, but i feel kind of down that an outcome would be drug oriented.

[@seoamazingfam]

12:44 How do you spell that region of the brain? It sounded like swaffa cortex but I’m sure I am misspelling it. 😅

[@renzoadriano2387]

It seems that the lecturer is refering to some part the Wernicke's and other from the Temporal Lobe area. Though, since she also mentions a link with dynamics perception, it may also include the Parietal Lobe.

[@michellemoony5609]

I am aspergers adhd anixaty depression hsp I don't really know much. About my self, and having cbt, therapy which I found OK, but my emotions are up and down, I care a lot and honest person, I love deeply and get hurt deeply, I don't have any friendships which last no longer than three years, I get used and because of being kind, and taken advantage of, my understanding is people talking about me and over worry, I am still learning can people with autism feel in women and why are we so kind, I don't like people shouting at me and I burst into tears, and understanding people is I struggle a word I don't know, or understand and thinking differently to my other kids who have the same but both think different to me, any help you can give me thank you cause in the UK they saying its mental health condition autism I try to understand myself, 😊😊😊

[@johnn2638]

I have high functioning Autism along with Anxiety.

[@AnatolKukula]

great lecture. 🎉 but can we find autistic audio technicians. so sound would be normalized, no echo, and reduce sensitivity for sounds like swallowing

[@internetfasting80085]

Presumptive inquiry, has no one realized that most increases in "disabilities" is a direct byproduct of the advancements in civilization? Like, cities arent natural, and humans didnt "evolve" to live in municipalities (with automation & commercialism). Maybe adapting to city life, but at best the last 500-1000 years was just a "transition" phase for a star trek future out of the mad maxx colonial periods.

[@felixwallace5041]

Diagnoses of high empathy/masking autism at 30; was born a woman but became a man at 22; i don't know that i would ever have been diagnosed if i had not transitioned- would love to see more research on my brain

[@edwardb7811]

What is the treatment if any?

[@matth3569]

Any clue on original cause of the malfunctions in the sensory and wiring to the brain other than genetic related?.. Possibly any environmental causes? Anything that might be causing brain damage in modern society from a young age? Any research into rehabilitation or cure? Any successful change in autistic folk?

[@psychedelictacos9118]

Nice to see a video on autism that actually delves deeper into the neurobiological mechanisms that underlie autism instead of just stating the characteristics and traits of autism!

[@yvn_ent4964]

Would you say that's why they show signs of OCD when they're little? Because they learn things in a certain order I reckon it's because they have no instant click For example someone is perceiving these colours and shapes however they remember it in a certain order so they have to line them up and that certain order?

[@sophiemcinnes5435]

How can I cite this? :)

[@hasanmahmmud9716]

Bangladesh must be deserver Neuroscience University

[@NG-cx1mm]

I miss food as a possible factor of influence. Our gut influences our behavior too?

[@marciamarquene5753]

G e muito muito muito boa noite e muito obrigada por ter vindo aqui e muitas alegrias sempre felicidades e muito obrigada pela atenção e muito obrigada pela informação e muitas alegrias sempre vcs estão fazendo as crianças e muitas alegrias sempre vcs estão e muito obrigada pela informação e muito obrigada pela informação e muitas alegrias sempre vcs merecem ser feliz por e muito

[@antoniopena3254]

This was amazing, i fell asleep not 2 minutes in! Finna give up the sleeping meds, thank you!

[@EverythingIsDivine]

There is most certainly a heart diagnosis for autism ..its quite simple...an autistic person speaks through the heart, and most of society speaks through belief systems. I know this becaise im autistic, and i dove into "why" i have communication differences...its because im speaking with an ignorant society of confusion...not to say that i dont have any problems...but atleast i live in the moment, and i think and feel whats going on "now, and not troubled by the past and the future. The soul sits in the heart, and thats what autism is...simply one who speaks yhrough the heart.

[@Wild4lon]

We definitely are a long way off. These results are *far* from conclusive and I think the main benefits of things like moving the diagnostic age from 4 to 2 is really not that important. It is far better if we can comprehensively map out what genes lead to what biological brain development signatures.

[@z0uLess]

If it has no essence, then the problem is not in the thing itself, but the backdrop of the thing -- the ground to the figure, if you will. Sociologically, we could possibly say that its a newly developed field from the development of expert systems and the overstructuring of society breaching into new demands on the structure of individual brains. It is not a problem in itself, but a problem of the questions we have decided to start asking ... its the cultural development and cultivation of individual emotional safety on the backbone of neoliberal ideology run amuck.

[@attacephalotes8892]

What about teaching people to be more open and less discriminative instead of searching meds to make us „less autistic“…?

[@oseadeniyi]

On medication, I seriously think it should only be with the approval of the individual upon discovery and development. Great insight and lecture, thank you. This was very helpful.

[@kanatsizkanatli]

Autism is a disorder of awareness ...as an autistic person who is aware of his lack of (or sometimes hyperactive) awareness, the answer is obvious to me now...but it has taken me 38 years to work out what was wrong with me. i knew something was wrong, i even got through medical school and 10 years of clinical practice yet to work it out! ... i think autism is a general disorder of the human mind that is primarily multi genetic (rater than a single inherited gene), I see many family links both personal but also links in the wider patient groups and the general public. There may be an epigenetic environmental connection too but my intuition is that no specific environmental agent will be found despite the obvious desperate attempts to find such a link such as vaccine cause etc...people don't want to think it's genetic for various psychological reasons but would rather think it's something external done to their kids. We should look at populations where autism is much more common and study these populations without prejudice.

[@f.u.c8308]

Look up the monotropism theory of autism, it's almost like you have figured it out

[@marciamarquene5753]

D fui dormir aqui agora tô falando w se for por causa dos meus amigos e muitas alegrias sempre felicidades e muito obrigada pela informação sobre as crianças e muitas alegrias e muitas alegrias e muitas alegrias e muitas alegrias e muitas alegrias e muitas e muitas alegrias sempre vcs merecem ser

[@Emotionallyattachedtorocks]

4:08

[@KupcakeKitty]

Have done research on adult brains that undiagnosed as child?

[@jlllx]

they have, they're the same. they found neurotypical brains don't exist.

[@jamescah9230]

The diversity of the autistic community, symptoms, and the differences mentioned here would imply that autism is more of a broad term for a number of "disorders." This was hinted at when talking about connectivity, and does not mean that there aren't universal factors. I have struggled my entire life. So I understand the desire for treatment, and why the term "disorder" is used. The term "disorder"ostracizationrecommended Other thoughts impoverished Certain peoples may not be as prone to autism as others. Despite the political landmine it is, especially right now, abnormalities like this can be useful. So koccurring Really not meant to be an insult, and likely has more to do with the recording, but their is a claim to be sensory friendly but didn't bother speaking at an octave that doesn't make me want to scream. High pitch is like being punched in the ear to me. It was a very rough half hour.

[@benjaminschooley3108]

My bro, people can't help how they sound, why not next time just hit the closed caption button.

[@jamescah9230]

@@benjaminschooley3108 I am certain it was the quality of the recording and was not meant to be an insult

[@Nekotaku_TV]

All autistic people share a few common traits.

[@BasedZoomer]

03:27 that color yellow is not sensory friendly to me. Why must they use such saturated colors? ugh

[@ChallengeTheNarrative]

Do they know you require a different colour?

[@johnvallsater4499]

I can't believe I am one of those she is talking about.

[@erika9353]

15:50 is why marijuana helps autistic people. Less connectivity between the different parts of the brain in autistic people, while marijuana increases connections between different regions of the brain. Yes I'm autistic and I smoke weed once a month. It helps me understand humans

[@awakenedsoul]

What else have you discovered?

[@stvbrsn]

I think it’s pretty simple, actually. I believe we (autistic individuals) are a genetic holdover from the preliterate cultures (think hunter/gatherer) that spanned this globe prior to written language, agriculture and cities. When the human genome project completed their genome mapping they announced that we had roughly 4% Neanderthal DNA. Well, that’s a spectrum too. What if autism is simply a phenotypic expression in those individuals whose genetics is comprised of higher levels, maybe closer to 10% Neanderthal genetics? In the parlance of our times... Jus’ sayin’

[@stvbrsn]

Paxton oops, I forgot to provide this link: www.nature.com/articles/453562a

[@MichaelShor]

@@stvbrsn What does pre-literacy have to do with autism? I am struggling to understand the connection you are making and the source of your hypothesis.

[@MichaelShor]

@O.o LOL exactly, and, for example, arguably dogs would be a good example. They appear to be able to read human body language, and they certainly can learn effective non-verbal communication with humans that allow them to get physical and emotional needs met.

[@deadsoon]

how would this hold up for people with no Neanderthal ancestry, such as native american, asian or african, that can still present ASD criteria? still an interesting observation i suppose.

[@cyndihall120]

Her pen clicking was driving me crazy

[@meufilhoautista2060]

Ready good study , if any one is watching this video In 2021 let get in touch . Send a reply I’ll send my contact we need more studies I’m a mother of 4 yrs autistic child and he been label as an autistic not giving chances as other kids. He is very very smart start read very early and understanding thing much better then many others adults and kids. We should get together

[@simonehanrath5991]

Lovely lecture, however: if the claim to start off with is that autism is a spectrum occurence, that is, that everyone on this planet is in one degree or another autistic. Then doesnt it make perfect sense that findings are not showing a single brain infradtructure that pin points "the autistic brain"? Im no scientist but it seems kinda logical that different studies with different people (both scientists who define the "authistic" group over the "control" group as well as the persons involved in tje experiments) get very conflicting results. It must be an incredibly complex task to make a consistent claim

[@JamieHumeCreative]

Overabundance?~ That's not negative bias at all...apparently this approach has a problem with saying more than usual. Heaven forbid that we have an advantage here!!! I see both the forest and the trees, the trees and the forest. Also, a forest isn't simply a bunch of trees. I love my brain.

[@tayday424]

I just came from Nancy's lectures on the human brain! I guess the neuroscience community is small.

[@jeice13]

What we call autism isnt necessarily one condition. It covers such a range of symptoms that it would make sense if the contradiction around 16 minutes is actually three seperate types of autistics

[@jlllx]

it's all cptsd. it's all caused from poor parenting.

[@jeice13]

@@jlllx that wouldnt necessarily explain the older cases that seem to have been passed down through family lines. Im pretty sure a lot of the symptoms result from the actual effects changing life experiences though

[@jeice13]

@@jlllx also when it starts extremely young trauma is a poor explanation

[@cutestkittensanimalrescuep8531]

If she happens to read this can she tell us what sections of the brain are affected instead of just showing us pictures and saying on the side behind the ear

[@davidgeorge4621]

I agree and looked this up. It is the posterior parietal cortex. It guides movement in space using the somatory sensory, auditory and visual sensory system inputs.

[@marciamarquene5753]

G e muitas felicidades sempre e muito muito lindo c BB BB GG e muito e muito obrigada por favor se ET r e muitas felicidades e muitos é muito difícil e muito obrigada por ter vindo as coisas ai

[@marciamarquene5753]

R viu e muitas alegrias e felicidades sempre e sempre vcs merecem muito difícil e muito muito muito é muito muito é só r e muitas felicidades sempre e sempre vcs estão lindos né amiga é só r e muitas felicidades e muito muito anos muitos DJ e muito muito anos atrás e se for por causa disso né se fala comigo e muito obrigada por ter

[@carriemyshkin362]

This is so concerning. I kind of wish I hadn't randomly come across it. Paying lipservice to "nothing about me without me" and peppering the language with reference to "differences" does little to distract from the fact that this talk consistently refers to autism as a "disorder" and in terms of "symptoms" (which is pathologising). It is bewildering that people with backgrounds in philosophy would do so little to consider what they're doing from a wider perspective (they aren't seeing the forest for the trees, diving straight in with the assumption that autism is a disorder and going - ever more wrong - from there). Research into "causes" of autism is unsettling and raises questions in regards to eugenics. Autistic people already experience disadvantages in society without that. Casually aiming for early "diagnosis" to facilitate earlier behavioural "interventions" (without, seemingly, making any sort of case for why that would be a good thing), is similarly chilling. Very young children can't choose to opt out of these "interventions". Adult survivors of behavioural "interventions" have spoken out about their experiences of them. The "double empathy problem" isn't referred to. Non-autistic people are erroneously told they all have autistic symptoms. And this person is being *paid* to say all these things, and to do the harm they're doing. This was 5 years ago. Hopefully things have moved on from here.

[@Monjagetitonya]

I have a question? How many women took an antibiotic before giving birth because of a vaginal bacteria? My daughter took this antibiotic and I’ve read that it’s thought that the antibiotic keeps the natural bacteria that covers a baby while coming thru the birth canal keeps brain synapses from being trimmed normally. Any thoughts? Thank you!

[@ChallengeTheNarrative]

Can women just apply yogurt?

[@KatherineVVE]

7:45. Where is data on Russia, Africa, India? Large population 🤔

[@RepublikSivizien]

5:35 those examples are not that simple either…not at all

[@marciamarquene5753]

C BB BB GG e GG GG GG e GG e GG e GG e muito muito muito lindo esse vídeo é muito muito muito lindo e muito muito lindo e muito muito lindo e maravilhoso

[@margueriteoreilly2168]

Mu son was Serverly Autistic non verbal Until age 9 half His Protocol now has him talking All symptoms gone A few stimms to bad foods He has Autism With no symptoms We are changing his his Cells Turning on his Michondria As they need twice as much Oxgyen than normal cells

[@alquinn8576]

when will people learn that long introductions are boring and tedious. can't we just assume the person invited is a credentialed non-crackpot and get on with it?

[@shvonned.burkemsncrnpagpcn619]

What if those with Autism don’t want to be ‘fixed’ or medicated ? Because they don’t think they’re broken, simply because they don’t fit in to a pre-determined structure.

[@josetavares9573]

I think in due time that the essence of Neuroscience will have a breakthrough Analysis on how to deal and cure Autism, especially in Children who suffer from this Neurological disorder disease.

[@JamieHumeCreative]

What I hear is that you want to dull us down rather than help our nerves. I love that extra information. OMG it would be horrible not having that. NTs may think they see the forest, but NDs. know what it is. It's a treed ecosystem not just a bunch of trees. We can understand both, Simplicity is at the root of every complexity. If you eliminate Autism, you will be left with predictable computers and will never have an Einstein again. The neuroscience is fascinating, but this is not a disorder. I love my Autistic brain the way it is. My ADHD and Tinnitus are disabling despite ADHD having assets which I love. I would never want to be NT. Not interested in Eugenics.

[@Jorbz150]

You have no right to dehumanize other people as "predictable computers" and then claim that those disagreeing with you are eugenicists.

[@ladystardust2008]

IT'S COMPLETELY MISLEADING TO SAY THAT EVERYONE IS ON THE SPECTRUM TO SOME EXTENT. JUST WRONG AND INCORRECT. REALLY WISH YOU HADN'T SAID THAT. THAT'S THE SINGLE MOST STUPID THING PEOPLE SAY TO ME. YOU KNOW NOTHING ABOUT IT UNLESS YOU ACTUALLY ARE AUTISTIC. THAT MAKES ME DISCOUNT THIS VIDEO AND EVERYTHING IN IT BECAUSE THAT'S A STUPID REMARK.

[@platynowa]

Sensory friendly, but the sound suddenly goes up. And no, thank you, for your behavioural interventions and drugs. This so boring froth filled lecture.

[@SamanthaSweetAnne]

56 hours of labor I addition to 12 hours of pain killers during labor plus vaccine damage caused my son to be nonverbal. I am autistic but verbal. Not everyone can process all those man made chemicals like folic acid found in cereal. We need folate! Why is folic acid put in everything!?! We have the MTHFR gene mutation. Our brain patterns are different because there is brain damage in certain areas to the point the brain has to reroute and therefore rearrange it's route. My son was born with a cone head. The result of local brain damage from surviving the contractions in their mom's womb. I also a c section baby.