7. Enzyme -Inhibition- 1.Reversible (competitive,noncompetitive), 2. Irreversible inhibition

[@mishganfatima2930]

Youre the reason i like biochemistry ❤

[@stayK1]

True

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Br.........

[@noorulshabika5619]

True

[@sudhatiwari1767]

And my school teacher are the reason I hate bio , chemistry , physics....

[@gurlinkaur5833]

​@@sudhatiwari1767 why do you hate pcb? Why are you even watching this? Itzzz for mbbsss dude

[@fatimaqasim7001]

Sir inhibitor binds with enzymes not to substrate.you mentioned inhibitor binds with substrate Lecture is very clear

[@primecoremedicos]

Sir I am mbbs 1st year student I want to say you just one thing Very very big thanks for these classes Thanks a lot from me and my batchmates 🥰🥰

[@bhoomikumat9976]

21:55 21:55 21:55

[@vidhathrisharma2278]

The way he is trying to explain the topics in his own words is just excellent ! Sir you are so better and awesome than compared to all those lectures who talk everything in English! Hats off to you for explaining and trying your best to explain the topics😎🙌 You explain So well ! easiest explanation ever!! keep up the good work!👏👏

[@125bbna8]

Thnx sir u made it easy keep uploading more and more

[@Rajesh_Jambhulkar]

Thank you

[@abhishekbhattacharjee1012]

U clear the basic concepts of biochemistry ur lectures helped me to score a good marks in biochem

[@dhanyaganesan1105]

Sir during reversible and irreversible inhibitors u sid that inhibitors bind to substrate..but I think inhibitors bind to enzyme

[@parmargopal1143]

Thanks you sir in first year student complete thair biochemistry with help of your lactur

[@faizanulhaq7285]

Sir u are true legend i like biochemistry bcz of u ❤

[@muneebaumar7173]

thanks alot sir from PAKISTAN ❣❣

[@drsandiplambe]

Wonderful and easy illustration of a difficult topic... Great Sir...

[@Rajesh_Jambhulkar]

Thanks dear

[@Maadurgaeducationshorts...]

Thank you sir ..all concept is clear

[@mathematicshub_latest9788]

Sir thank you so much ,sir aapke lecture se study m bhut madad hui

[@sayedsajid2529]

I watched this with the playback speed of 2x but... it's much informative 😊😊 Masha Allah 😊❤️

[@rashmimandave5054]

Sir plzz make a video on isoenzymes and its diagnostic importance

[@pratapgouli9439]

sir your lectures has helped us a lot during this lockdown thank u very much

[@AbbasKhan-sb1xo]

Teaching method is good sir g 😊😊

[@abrahamdeuapiok3497]

Thank u so much Doctor❤️❤️❤️, u make everything simple to understand

[@chaplainkim6219]

U always make fall in love wit Biochemistry

[@chestapant1406]

Thank you so much sir coming up with so many lecture series of biochemistry 🤩🙏👍👍👍

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An Absolute pure Lctr and easy understanding ❤

[@krishnatomar5944]

Excellently explained..thank you so much sir for helping the needy ones.. May god bless u.

[@rabibaali1051]

really your lectures are.....so helpful sir thank you.

[@Mediksam8]

3:09 inhibitor will bind to the ENZYME rather than substrate by non covalent interaction in reversible inhibition...

[@mihirmakwana9012]

Yes right he said like that 2-3 times .. He said inhibitor binds with substrate but inhibitor binds with enzyme

[@AdwaitRunkar]

One of the best biochemistry channel I have ever came across . Sir , you made this topic crystal clear . Thank you so much sir 😊😊 And Happy Diwali 🎉🎉🎊🎊❣️

[@atharvakokaje5818]

Really good explaination sir🤩🙏🏼 Thanx a lot

[@jennalyndonjagroop5809]

Thank you Professor☺️. You make Biochemistry so easy for me

[@nehasultana1415]

Thank uh so much sir dis has helped me alott to clear my doubts regarding enzyme inhibition

[@Priyanshuplayzzzz]

Hi neha

[@unknown-xf5rw]

Sir you're god for me 🙏🙏🙏🙏thank you very much sir.

[@RamanDeep-sz1mf]

U teaching is perfect

[@kowsalyakowsi2478]

Thanks u sir your teaching is very good and easy to understand 👍

[@atikaananna8754]

Thanks a lot sir from Bangladesh 🇧🇩

[@medico5496]

DFP nerve gas = (-) serine proteases and Ach Disulfiran - used in ethanol addiction Bcoz it inhibits Ac.DH and leads to accumulation of Acetaldehyde.

[@shristisingh354]

Very nice 👌 explanation sir

[@KamalKhan-r8f5s]

First I hate biochemistry but when then I see your lecture now I love biochemistry

[@Rajesh_Jambhulkar]

Good to hear that Thank you 😊

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good work sir..nice video plz uploaded more video from biochem...

[@robertbingo8405]

I have really enjoyed the lecture 😊😊😊

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U can make it easy the biochemistry some difficult topics also we can understand nicely all credits goes to u only sir😁

[@sauravpurushothaman4808]

U are simply awesome sir

[@sumanbhunia4836]

Thank You Sir, Radhe Radhe Radhe-Shyam, 🙏।

[@hashman2145]

5:16 pe is it weak or beak enzyme

[@ujjwalbhardwaj9788]

Jai mata di

[@ashwinijantikar2327]

Very precise and accurate explanation sir....👏 👌 🙌

[@harshitapandey2924]

Great work sir.. Please carry on🙏🙏🙏

[@KSANGA-m5z]

Nice work sir keep making videos like these

[@sumans2884]

It was really helpful sir... Thanks a.lot sir...Sir can u plz make a video on regulation of enzyme activity

[@Mediksam8]

Thanks alot sir for your great effort ,due to your work sir we're able to absorb the concepts.

[@kunchalachandrika6172]

Thank you so much sir for spending your valuable time to us. It has helped me a lot

[@ishuadhikari7085]

Thank you sir..greatly appreciable video💙

[@nidhiparikh6359]

Sir one query, non competitive inhibition is a type of irreversible inhibition right? As even on increasing the substrate it's not going to have any reversible effect ...

[@bee3348]

Yaa i was thinking the same

[@asha.k5336]

It is really a helpful one Thank u sir U made this easy

[@Rajesh_Jambhulkar]

Thanks

[@sankarm8983]

hi

[@vidyak7440]

Gd mng sir. Non competitive inhibition is reversible or orreversible. Some text book it noted irreversible.

[@Balugoud1008]

👌👌👌👌👌👌👌👌👌👌

[@rishigupta5792]

Respected sir, In vasudevan, non competitive inhibition is given in irreversible and also written that inhibitor combines with enzymes by forming a covalent bond. Sir please clarify it. Thank you

[@Rajesh_Jambhulkar]

Content is taken from Tietz textbook of Biochemistry. Non-competitive inhibition is sometime irreversible. In some books Competitive and Non-competitive mentioned while in some non-competitive is mentioned under reversible inhibition. Vasudevan is good book. Just follow any one book for this topic.

[@ajayfacts81]

That's a flaw of research. Scientists are divided in two groups regarding this

[@shilpaaswal6469]

This video is so helpful for me ...thnku Sir

[@welcometosagnicksworld3894]

Sir inhibitors binds to the enzyme or substrate?

[@jwalantkumaragravat32]

Sir I have 1 question regarding non competitive and uncompetitive inhibition Why km value is not changed in non competitive inhibition because when inhibitor binds with ENZYME or ES complex ( binding site for I and S is Different) but inhibitor will not decrease the affinity for substrate, because it cause some conformational changes at catalytic site ???

[@Rajesh_Jambhulkar]

In noncompetitive inhibition Inhibitor does not affect the binding of substrate to the enzyme. It's efficiency to convert the substrate into the product is decreased.

[@jwalantkumaragravat32]

@@Rajesh_Jambhulkar Thanks for the answer

[@nirvabaria6142]

❤️❤️ great explanation ❤️

[@noroz1900]

You do Great work for Students

[@priyasany8184]

Thank u so much sir....it is very helpful😇😇

[@maheshswami5226]

Sir mixed inhibition and suicidal inhibition par bhi video upload kijiye please 👍👍👌

[@adithyashetty1868]

Make a video on enzymes used in diagnosis u r super 😉

[@mayanksharma7504]

very good lecture. Thanks sir ji. now my concepts on enzyme are clear.

[@studyholicmedico1582]

Thankyou so much sir. I only follow you and vasudevan book , not my professor :P.. :)

[@marymargaretfreeman8115]

Can you possibly do an introductory tutorial on Enzyme and Protein interaction? I am trying to understand the basics and this is a little bit too advanced for me right now.

[@GauravDash007]

❤❤ Celebrity Teacher

[@alokraman5368]

Sir is Lippincott good for enzyme activity

[@footballmaniac777]

Thanks Sir...From Pakistan ❤️

[@93-suchetaghosh76]

Thank you a lot sir.Because of your videos biochemistry is getting crystal clear to me.

[@Mehaktyagi03]

Sir please make a video on myocardial infarction it is very much needed!!

[@jitinsahni2441]

Sir 3 types are there 3rd one is allosteric inhibition you told only 2

[@rashmimandave5054]

Thank u so much.. Plzz keep uploading biochemistry vie

[@souravghosh7173]

Nice video. Just one correction- the L-W plot for noncompetitive inhibitor is to be corrected.

[@Rajesh_Jambhulkar]

Yes, thank you for correction. Not noticed yet. Always welcome

[@sankarm8983]

what is mean L-W@sourav ghosh

[@souravghosh7173]

@@sankarm8983 lineweaver burk plot

[@sankarm8983]

thank u @sourav ghosh

[@sankarm8983]

what u doing bro

[@kiranraut5207]

Very useful video sr

[@Wanizeeshan786]

Sir I have a bit doubt..... fluoride inhibits enolase...is this non competative or irreversible inhibition???? Rest Thank you for your generosity ❤️

[@bee3348]

Noncompetitive

[@Wanizeeshan786]

@@bee3348 thank you

[@virajhajare6914]

Ethanol is food drug and poison ..... depending upon the concentration

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sir , I think we are prepared in u. satyanarayana biochemistry book.

[@Rajesh_Jambhulkar]

thank u for giving ur valualble time, not getting u,plz specify

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Sir does dietary cholesterol inhibit cholesterol synthesis?

[@goldenlion902]

Sir I want to ask that many lines u said verbally like u said about metabolites so do we have to note that too ?

[@Asquare369]

Awesome😍😍😍

[@wasifullahdawar6962]

Inhibitor bind with enzyme not with substrate in reversible and irreversible reaction

[@Rajesh_Jambhulkar]

Yes

[@Ss-cy4rr]

Very well taught sir

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Super explaiation sir ❤️❤️

[@iloveroronoazoro1316]

Sir do you have any physiology channels you would recommend??

[@raotanzeel8715]

Thank you very much sir 💕

[@gomathisendhil2496]

Non competitive is irreversible, ....

[@chatlawarhanmandlu7384]

Sir y vmax remains unchanged in competitive inhibitor

[@man-ios34]

thabnk for help to over come my exam sir

[@tashmiyatanweer3999]

Thank u soo much sir🙏🙏

[@aqsashah6238]

Great Job Sir 😊❤

[@k.vishwateja7204]

Please use dark sketches it is not appearing

[@NAVEENKUMAR-xe1nl]

I have only 15 days to go for exam.......15 days enough for prepration of biochemistry ? Will my preparation be completed in 15 days?

[@Rajesh_Jambhulkar]

Yes,do it. Best luck

[@rajyashreebanerjee5033]

How non compititive inhibition is called reversible though they are not overcome the inhibition in case of increasing the concentration of substrate....????

[@rahulmooshahari4772]

Sir my answer is-- (a)- Alcoholic liver disease. Is it right sir?

[@Jimmy25442]

You're awesome Sir.

[@nainak8699]

Sir fluoride bulbs means?

[@maheshswami5226]

Lecture was awesome

[@kanhaiyasharma893]

Sir you provides written note also ??

[@apoorvadixit1974]

sir kindly reduce the no. of ads per video

[@satendersewal8119]

Very helpfull 🙏🙏