C-Reactive Protein (CRP) | Inflammation | Acute phase reactant

[@soufianeelhabachy8171]

CRP is a marker of inflammation c protein is an inhibitor of factor 8 and 5 in the coagulation process c peptide is a chain of amino acides produced in beta cells of the pancreas , it comes from the clivage of proinsulin .

[@MedicosisPerfectionalis]

Excellent

[@timlee8823]

Don't get crp test is you had a vaccine, injury, cold,etc. Wait until you feel OK to get accurate results

[@newdaV1D001]

@@MedicosisPerfectionalis You refer to CRP in your video as an "active" compound of the immune system, hence the "reactive". Therefore and for my understanding, and from what I can read in the literature, CRP is far from a mere "biomarker". It can be used as one, but the classification is wrong by your own statements in the video. TroponinT is a biomarker, as it is part of cardiomyocytes. It is released into the blood stream after heartmuscle damage and can be measured as a sure indicator of myocardial infarction and dying cardiomyocytes. CRP in contrast is a pentraxine, just like antibodies, and has the capability of detecting "foreign to the body", as you said, like bacteria, and non-physiologic, like necrotic cells. Even further it is able to not just recognize necrotic, therefore already dead cells, but also dying cells (that may become necrotic and would be posing a threat to be body in the future by becoming septic), that still have the capability to regenerate. Wherein lies the problem of CRP not being able to differentiate between already dead and gone cells or cellmembraneparts, bacteria and not yet dead cells. COVID-19 was the best example for a viral infection, with a massive uptake of CRP-Synthesis right before patients with pneumonia would ventilators and eventually died later on. The publication here descibes the active role of CRP in the cause of illness and cell damage. I highly recommend it: www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.630430/full

[@benwearne542]

Your sarcasm helps me remember everything

[@MedicosisPerfectionalis]

Awesome 👏

[@holden2966]

C peptide is a component of preinsulin, which binds two alpha chains of insulin molecule. C peptite test is done to differentiate type 1 DM from type 2, because c peptide is available in the body only if there's endogenous insulin secretion

[@aimz_med]

CRP is an acute phase protein C peptide is part of the proinsulin which is cleaved off before release Protein C is an anticoagulant in blood 😊

[@DurdyD91]

This is the first vid I am watching from this channel and I am only 7 minutes in and I already love this guy! Funny and educational! Defo subcribing. Thank you!

[@MedicosisPerfectionalis]

Thank you so much 😊 I am honored! Can you please help me by sharing?

[@jayking2762]

Agree 100%. he is humorous and very educational. 2 thumbs up!

[@ShamuAdism]

greetings from Indonesia im a HLAB 27 autoimmune patient, have a high number in my CRP been diagnosed since 2002 , love this channel

[@lilchadzy121]

Currently in the process, still awaiting my hla b27 results but it turns in my fam. My crp was moderately high and my symptoms are looking like ankylosing spondolitis. Hope you're doing well!

[@ibrahimbashimam9149]

this is hilariously educational

[@MedicosisPerfectionalis]

Awesome 👏

[@cabdallahcabdallah4717]

@@MedicosisPerfectionalis is crp 10 normal with thyroid problem? Thanks and Esr 7 mm

[@sanjanathapa8078]

@@MedicosisPerfectionalis जकगजजथकगकगकगंकगंदजथ

[@chuckhoffman8680]

@@MedicosisPerfectionalis😅😅😅😅😅

[@yasseral-ghabra9518]

C-Reactive Protein is acute phase reactant / Protein-C is innate anticoagulant / C-peptide is a part of preinsulin

[@MedicosisPerfectionalis]

Cool 😎. How would you differentiate between fictitious hypoglycemia and hyperinsulinism?

[@ahmed621989]

@@MedicosisPerfectionalis in hyperinsulinaemia, c-peptide is also elevated, but not in factitious hypoglycaemia

[@MedicosisPerfectionalis]

What if the patient with fictitious hypoglycemia is abusing sulfonylureas instead of insulin. How would you differentiate between fictitious hypoglycemia and hyperinsulinism due to tumor?

[@yasseral-ghabra9518]

@@MedicosisPerfectionalis Levels of C-peptide

[@MedicosisPerfectionalis]

How come?

[@Nat524Ricci]

I love your videos. But also, knowing your love for complex conditions, I would LOVE to know your thoughts on my lab results! I am a very complicated and rare individual, and am finally getting the proper health care that I’ve needed for the past 15 years. Keep doing what you are doing - your passion radiates though your videos and I appreciate the stable and confidence source of knowledge that you share!

[@MedicosisPerfectionalis]

Hey! You can send me an email: [e-mail]

[@Nat524Ricci]

@@MedicosisPerfectionalis awww! Thank you! I will. 💜

[@MedicosisPerfectionalis]

Thank you 🙏

[@dknc7393]

@@MedicosisPerfectionalis I think you said you are "no doctor" and I understand the "liability", but I've been trying to help my mom with her unintended weight loss the past 2 years and then I stumbled across your channel. I have learned and ordered tests outside that her medical doctor would not do or don't have and they could not find out why and reported as idiopathic weight loss. Seeing this other person's request, I wonder if I can also send you some lab results to get to the bottom of the mystery. I greatly thank you in advance. ❤ 🙏

[@dawnmarcelisbendig2667]

I have learned so much from your videos. I am trying to be more active in my health care dealing with my connective tissue disease and your videos have helped me understand my lab results. Thank you.

[@MedicosisPerfectionalis]

My pleasure 😇 Keep fighting the good fight! Good luck 🍀

[@aprildooley8457]

"I will diagnose you on your crp..said no doctor ever" except my husband's rheumatologist. BTW, he was bit by a tick, his ANA was 1:40, and she prescribed Methotrexate. I said no, no, no prescribe him doxycyline. 3 days on doxycyline and he went from bedridden to ready to go dancing.

[@SalilTV]

This is edutainment at its best ! Great video - explanation as well as graphics ! Thanks.

[@MedicosisPerfectionalis]

My pleasure 😇

[@MSmusic65]

So good. I love this. Subscribed because you are educational and funny. Those boring teachers at uni just lost their job to you!

[@MedicosisPerfectionalis]

Wow 🤩 Anna, you are the best! Thank you so much 😊

[@VKell]

Love it :-) I am BSN-RN and currently taking FNP. thanks for the info. you made the lecture fun.

[@18ignat]

CRP and ESR are not markers of INFECTION BUT OF INFLAMMATION! Just a reminder :) Great video, cheers man!

[@sabasiddiqui429]

But infections cause inflammation, right? In tuberculosis there is inflammation because of infection. So it can be both.

[@user-sq3ls6sj7i]

​@sabasiddiqui429 inflammation is more general, not every inflammation means infection

[@jayking2762]

Excellent, style, and delivery, bravo!! you are very gifted!

[@MedicosisPerfectionalis]

Thank you 🙏

[@rachelx1379]

Thank you for the video very informative as I had no idea what it all meant! I’ve just had a blood test & my CRP is 5.57. No fever or pain etc. Heart disease and strokes in my family so have made an app with my gp.

[@MedicosisPerfectionalis]

Making an appointment is the right decision...Don’t think about lab result without thinking about the whole picture.

[@ahmedtzaki4476]

‏‪3:49‬‏ By the way, I have found some difference between pneumonia and pneumonitis! "Pneumonitis (noo-moe-NIE-tis) is a general term that refers to inflammation of lung tissue. Technically, pneumonia is a type of pneumonitis because the infection causes inflammation. Pneumonitis, however, is usually used by doctors to refer to noninfectious causes of lung inflammation." (- Mayo Clinic)

[@tiazadobbs7475]

Mine was 3.30. Icu for pneumonia and two pulmonary embolism. Thank you Covid.

[@isabellopez6755]

Oh what a great video! I also love Latin! Thank you for the videos !!!

[@1rrrrrrrrrrr544f]

I love the opening theme

[@MedicosisPerfectionalis]

Thank you!

[@itsqueenbeautiess9552]

My CRP Value is : 1.70 mg/dL My labs Standard Range

[@subashp9663]

Great explanation

[@MedicosisPerfectionalis]

Thank you 🙏

[@gelsayedpt]

To the point man, love how you make it ssssso ssssssimple

[@MedicosisPerfectionalis]

Thank you 😊

[@faridaakbari7591]

Heeeey! I think, it's first time that i watch your channel it was outstanding and motivational! Loveed! Subscribed🧡

[@MedicosisPerfectionalis]

Thank you 🙏

[@thelostvoicedieverlorenest8487]

You are a genious! and you help me with analyzing the problems Covid creates.

[@MedicosisPerfectionalis]

Thank you!

[@haqzahoorul]

Wonderful teacher. 👏👏👏

[@MedicosisPerfectionalis]

Thank you 🙏

[@lyzeldyan1507]

information and sarcasms? ICONIC DUO

[@JK20..]

The intro of the video is on point😂😂😁

[@Photoguy15]

Listening at 2X speed to you is hilarious ;)

[@MedicosisPerfectionalis]

😂😂😂

[@mohemmedmohsen3225]

Maaan, I love these videos

[@MedicosisPerfectionalis]

Thank you 🙏

[@mariocesarbenitez5552]

Thanks so much

[@MedicosisPerfectionalis]

You're welcome!

[@fatemaabbas1861]

Hi interesting video thankyou for educating us. Just a question im a female 30. My ESR was just by 2 points high at 22 but was recovering from a cold. But CRP was normal 2.2 Does that mean anything?

[@eliascorrea8573]

Great also for immunology! go watch the video and stop reading comments.

[@MedicosisPerfectionalis]

Haha 😂

[@bushmechanicadventures3356]

Mine is at 188mg/L, had high fever and joint pains for 5 Days, just had 3 days of strong antibiotics, tested again today and still at 188mg/L, doc says the infection is in my lungs. Lungs feel completely fine

[@samrafarooq830]

How are u doing now Mine is high too

[@abc_cba]

9:25 that was the girliest voice I've heard ! Funny :) thanks for the videos.

[@HadleyandRachelrun]

What if you always have a high CRP? My CRP is check about every three months and is always high. When does the acute inflammatory marker become a chronic inflammatory marker?

[@rawanalzehair4714]

Hello sir , thank u so much, I have question, Is CRP increase in both viral and bacterial?

[@trustinalqadir2982]

Nice vedios. And method was great. Today my Mother's ESR IS 25mm/1hr. And Eosinophils 08% I am confused to which Dr we should consult.She is sleeping to much.drowsiness feeling is also please suggest me

[@simonbreidert5683]

Great! Would love to see more about preventive biomarkers!

[@MedicosisPerfectionalis]

Like what?

[@simonbreidert5683]

@@MedicosisPerfectionalis in-depth mechanisms of all pro-inflammatory markers and maybe how anti-inflammtory cytokines counteract.

[@chrismallory1167]

I met active lipid at Purdue. She was 235 lbs

[@alaamincr]

thank you so much , it's amazing, very helpful in learning and refreshing medical memory , it's great way to get both basic and advanced med knowledge , the best way to be addicted with CME . excuse me I've a question : CRP : its role in the evaluation and monitoring disease activity , or flaring of SLE ? because we have been learned that high CRP in SLE (only SLE ) means there's a possible comorbidity or infection and we should rule out it ?!, or the negative CRP in SLE means nothing ? may you give me your explanation and opinion ? thanks

[@alaamincr]

the age of patient divided by 2 plus 5 =the normal range of ESR , so do you agree with me or it's not accurately method ?

[@ysllin9635]

well done and so entertaining at the same time ! good partner for quarantine! LOL

[@MedicosisPerfectionalis]

Thank you so much ☺️ Stay safe!

[@debbiegorsalitz1539]

You are amazing! Thank you.

[@MedicosisPerfectionalis]

My pleasure 😇

[@lenaalsaleem3769]

I loved your explanation, keep up the good work!

[@MedicosisPerfectionalis]

Thanks 🙏

[@musangilaiebalanga6040]

The 3 are different and are not correlated. C peptide is the remaining product after insuline is realised from the storage center in pancreas. It insulin is linked with c peptide while on storage in the pancreas. Protein c is bleeding factor

[@NiRioMas3]

“I hate myself” 🤣. Nice video. In Latinamérica we say “traUma” 🤓

[@sujatasood9991]

Thanks for v .good video I am 32 plus and diagnosed with ibs along with celiac since one year now in the month of this March my crp was 14.80mg/L and lymphocytes 3.50 (X10A3/uL) plz do reply is it dangerous sign as i feel continuous cramp inspite of all precautions of eating but doctor did not told me any thing ?

[@anaraquelmendoza4087]

Hello friend, firs of all great video. I would like to know if C- Reactive Protein, Quant is the same?

[@radouanek7708]

Does CRP also rise in response of viral infections/ viral induced inflammation ?

[@lajwantishahani1225]

Love your video and subscribing to learn more from you. My CRP report today had the value at 7.35 which I get is high but not too high, but while the report doesn't seem to cover ESR other parameters like creatinine and uric acid are high, and for the first time cholesterol is all over the place. Previous tests have reported some injury to the kidneys. Could you please explain that to me? Btw, I recovered from Stage Zero bladder tumor almost five years ago. Will be doing my pelvic ultrasound within a week so hopefully that can throw some more light so that I can get a better handle at how to clear this new inflammation. Or did it ever go away?

[@deepashriramesh51]

Hello sir,lots of love from India,your videos are absolutely amazing. Just one doubt, crp Half life is 18h right?

[@suzana.h.h]

Amazing 😍

[@MedicosisPerfectionalis]

Thanks!

[@DoniyorToraqulov-pl6pk]

Great i love your channel

[@Scrubsandscreens]

Difference between crp and crp quantitative

[@elianastone7124]

"Go to hell bacteria!" Love this video, educational and engaging! Keep up the good work!!

[@daph9843]

i love your hilarious approach HAHAHA thank you!

[@MedicosisPerfectionalis]

You're very welcome 😊

[@zach110]

This guy is HILARIOUS! Haha keep up the great work!

[@MedicosisPerfectionalis]

Thank you 🙏

[@منىعبدالخالق-م2ذ]

Thaaaaanks for your usual amazing explanation 🌸🌸🌸🌸

[@MedicosisPerfectionalis]

My pleasure 😇

[@intuitknit]

Could the obstetric complication be preeclampsia? In that case their is supposedly inflmmation in the placental attachment blood vessels.

[@shrisharma7355]

That's super informative and you're really witty. :D I was wondering, what does it signify when esr levels don't fall down post covid recovery? I've been tested positive twice since last year. And ever since that, esr and CRP levels never returned to normal range. I'm not facing any physical discomfort whatsoever. Yet the readings. Should I be worried?

[@CaptainVelveeta]

I'm no doctor but no, you shouldn't be worried. There are all kinds of labs that may read high but are not treated because the patient is asymptomatic. Throw in the fact that we know nothing about how Covid-19 works, lives and plays, as long as you're not symptomatic then there's no need to worry. I would, however, advise increasing activity to strengthen the lungs. That's always a good idea regardless of the condition.

[@sillypantses]

Would using DHEA lotion put people at similar risk to the contraceptive pills?

[@gregd4391]

What is ESR is normal, but CRP is 13. Is a higher CRP expected for a high-level, competitive power lifter?

[@drmukeshpatel1348]

Best video nice teaching way ever..really appreciate

[@MedicosisPerfectionalis]

Thanks, dear :)

[@MA-dd9dd]

Very informative

[@MedicosisPerfectionalis]

Thank you 🙏

[@dr.labanizaman55]

You said half life of CRP is 7 hours but in Davidson it is 18 hours. Could you pls clear the confusion??

[@leonardops09]

Hahaha gracias amigouu gringou, love from Peru! Great videos!!!

[@davidcobb7047]

I needed this information. Loved it.

[@TheseAreShapes]

Just got tested at 65.7 mg/L - yes I wrote that right! 😱 hopefully my doctor will explain it to me

[@MedicosisPerfectionalis]

Best of luck! Don’t jump to conclusions based on one lab test! Talk to your doctor!

[@piaakasyapa]

What was the result and treatment you hve taken...tell me

[@TheseAreShapes]

@@piaakasyapa ulcerative colitis- prednisone 40mg daily

[@TheseAreShapes]

@@MedicosisPerfectionalis yes, if you're curious the result was ulcerative colitis

[@paulg9229]

@@TheseAreShapes for how long do you need to take?

[@umamaheswari6699]

Nice sir.. Moreover we are looking forward to some of the microbiology topicss

[@kaitsakey6495]

My PCP seemed to get jealous today that my naturopath ordered c reactive protein. So they ordered ESR. This made me laugh

[@RodrigoOshiro]

i have chronic urticaria for over 7 months, my allergist tested crp and erp and they were both low, 0.34mg/L and 2mm/1st h so it puzzles me how crp is low with so many itches on my skin and sometimes swollen lips.

[@purplestar299]

Hi! I know that you posted this 2 years ago but did you ever get any answers? I am also suffering from chronic uticaria and i do get swollen lips at times. However my CRP is high

[@DrReginaldFinleySr]

Great video. Thank you for sharing!

[@MedicosisPerfectionalis]

My pleasure 😇

[@dimaria8029]

So much thanks🙏🏼😊

[@MedicosisPerfectionalis]

My pleasure 😇

[@mdemonchy3099]

CRP- Result 3.00 Normal Value 6.00 Any problem sir

[@MedicosisPerfectionalis]

We can’t confirm or rule out any diagnosis based on CRP alone...You need to see a good doctor, get a history, physical exam, and maybe other labs. Good luck 🍀

[@jarraies4939]

@Md:Emon Chy was your crp value 3 and normal value was 6.this was what you meant in your sentence.i am really sorry english is not my first language.That's why I am asking you

[@arifmarwat5973]

Please correct cystic fibrosis is autosomal recessive not Dominent

[@sphesihleidentical2334]

your jokes makes me enjoy and understand your lecturer " shup-up"

[@MedicosisPerfectionalis]

Wow 🤩 Thank you 😊

[@shahabuddin6149]

Great lecture thanks alote sir

[@MedicosisPerfectionalis]

My pleasure 😇

[@paulojustinianookubo]

I have high crp 10.9.. my symptoms are joint pain headaches abdominal burning pelvid burning. I have been tested for everything under the sun and everything comes normal. I am lost on why is very high.

[@osawaruenorense1596]

Have you visited your urologist. Get a PSA testing.

[@osawaruenorense1596]

Or better still try another laboratory for another blood test.

[@manarmaz1843]

C reactive 12.20 what does it mean?

[@tanyailoveny1176]

Mine 18 . Went up from 10 two weeks ago.

[@dragnsmeldy3566]

I am a minor, still in high school, so if I sound like an idiot, please forgive me. For around a month now I have been having intense pain around the nerve root near t6 or something like that, and the pain has been moving. I have been In a lot of pain as I breathe, sometimes the spots it hurts to breathe change. In the last week, I have been experiencing unexplained nausea and vomiting, which has been a nightmare. In a very recent blood test, it was shown that I have inflammation and/or high crp ( I don't believe they told us the exact number though) and my doctor has ordered an MRI with contrast. We still haven't been called back for the appointment to be made, but it has been approved by the insurance company. I am honestly a bit overweight, and I do have hypothyroidism, which is being treated, but everyone is telling me it is not my fault. I'm scared in all honesty. Do you have any advice for me and what I can do to help the stress of it all?

[@MedicosisPerfectionalis]

I think you should listen to your doctor; Do the MRI and wait for the results.

[@dragnsmeldy3566]

👍

[@oneseeker2]

Viral Pericarditis? Pleural Decisions in lungs? Dr could have seen this in X-Ray!

[@nasrinrastegar980]

Man you are fantastic!

[@m.janusiga1825]

Can you tell me my crp level is 3mg/dl(reference range is more than 8mg/dl is slight inflammation).but my esr is 43mm/hr.my doctors are confused.

[@susannahwhite7561]

Excellent!

[@GoodFilmStudio]

1:21 Ain't things other than proteins like katecholamines, androgens, T3, or Platelet ACTIVating Factor also active?

[@tanyatanya8808]

Did my blood test nd my crp was 3.5 MG dl And my cholesterol was little high too Should I be concerned nd go to a doctor or should change my diet for a month nd den go to doctor

[@AryanKhan-zc4lh]

Sir mera CRP test 6mg/L TLC(WBC)4000.....11000 C/mm 4700. aya h kya ye high h ya normal plzzzz btaye Sir

[@ghizlanet8276]

first thank you for your video !! but i got a question. Are cancers always accompanied by an increase of CRP? because cancer progress is generally silent, the cardinal signs of inflammation are not always there.

[@MedicosisPerfectionalis]

Good question! Not always

[@b.i.k.i.b.i.k.i]

@@MedicosisPerfectionalis Gotta say I loved your video! I chuckled… I never chuckle whilst watching medical videos 😄 If I may ask, can a person with a CRP result of 1 have cancer? TIA You have a new subscriber 👍🏻

[@davidcunningham2984]

very funny. would love to see you cover more general health topics such as heart disease diabetes covid 19 etc.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@kcc531]

I enjoyed watching this so much. You're hilarious mate.

[@MedicosisPerfectionalis]

Thank you 🙏

[@kashifafridi4974]

My Crp is 24mg/L what should i do? I have severe pain in my Left Foot ankle and Toe Joint?

[@cherrrriii]

why did u mention "Quelling reaction"? couldnt link it to the definition 😭😭

[@mjrosales5986]

Is this dangerous? I have 30.18 crp

[@victoriamattiello7090]

I love your intro and your videos, thank you!

[@MedicosisPerfectionalis]

My pleasure 😇 Thank you so much for watching!

[@timlee8823]

Vaccine can raise crp levels. My shingrix vaccine was on Sunday, and Tuesday my crp was 19. Yes 19. Next month it was rechecked as was esr, results, my crp

[@dh6320]

My score is 6 and i recently caught covid and then went ahead and got the vaccine about 3 weeks afterwards. I wonder if thats why my score is 6. Ill retest in a couple months and see if there is any improvement

[@TheBohoSol]

My level is 34. I had Covid two months ago and not sure if that’s why

[@manarsmaan2624]

losing your mind right now is better than losing 🤣 in the test . I agree

[@MedicosisPerfectionalis]

😊😊

[@rozacielo7792]

love your informative videos ... but please do slow down , its not easy understanding you when you speak so fast. Thank you

[@MedicosisPerfectionalis]

Thanks-dear-for your feedback

[@runalong]

You can click the little gear/cog setting button on KZbin, and adjust the playback speed to .75 or .5 x and that will slow things down 25% or 50%.

[@manjup1807]

CRP test is Negative. What it is showing? Please explain