Calcium Homeostasis and Parathyroid Hormone - PTH

Anatomy and Physiology. This video covers the regulation of blood calcium especially when blood calcium decreases. Including Parathyroid Hormone PTH signaling and its target organs like bones, kidneys and intestines.

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[@celestea3407]

Basically: Parathyroid detects ca+ is low and sends PTH to help get it back up into blood stream. 1) PTH robs calcium from bone, stimulating osteoclast activity while decreasing osteoblast activity(can lead to osteopororsis fyi). 2) PTH tells kidney not to urinate and send it back to blood. 3) PTH and Kidney work together. Kidney releases activated Vitamin D(calcitrion) to convince small intestine not to poop out the calcium. PTH is like a dark hero.

[@Juicy71320]

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[@basalsoon2]

what happens when blood contains too much calcium? hypercalcemia

[@chriss.1511]

When calcium is elevated then PTH levels decrease. This signal (or lack of signal) tells the kidneys to excrete more calcium in the urine (less reabsorption) also calcitriol (active vitamin D3) decreases which would reduce the absorption of dietary calcium in the small intestine. These responses should help return calcium to normal. Also lower PTH has effects on the bones too. Another hormone Calcitonin would increase, this could help reduce calcium too.

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