Can B-Complex be Harmful?

I'v see your channel is very good. More people need to know your content!

[@Jana-lv6re]

Thank you again for the great content Dr. L. Could the issue of source of B6 play a role too? Many supplements have inactive form which is pyridoxine not the active one (pyridoxal-5-phospate). And I read that B6 pyridoxine can lead to B6 toxicity..

[@Dr.WenliLiu]

Thank you. PLP is dephosphorylated before its absorption. As a replacement method, PLP is not necessarily superior. B6 is easily available in food sources. Supplementation is very rarely needed.

[@claudiafarcas8135]

Very good 🎉🎉🎉

[@fiery.mercaba]

One thing sadly lacking from this presentation is what forms of the named B Vitamins were entailed in each of the studies, as well as a laying forth of what are the benefits & known or possible downsides of each. For example, there is the B12 form called cyanocobalamin & it is not only inferior to methylcobalamin by being synthetic, but cyanocobalamin is comprised of cyanide & implicated in bad outcomes from taking it, & yet it is what many food manufacturers & the pharmacuetical industry's majority of entities gravitate towards for ingredient in their products. The type of B Vitamins must be a part of the examinations & discussions, for sure.

[@Dr.WenliLiu]

Thank you for your comment. The most common form of over the counter vitamin B12 supplement is cyanocobalamin. I have not seen any RCTs comparing health effects of different forms of B12. If you know any, please share.

[@fiery.mercaba]

Hi, @@Dr.WenliLiu, & you are welcome. And thank you again for your video on which I commented. It is just that the information lacked any mention of the different forms of Vitamin B12, but you acknowledge this now, I think, & I suppose I will also say the lack of mention was somewhat occasioned by the lack of mention & differentiation in the conducted researches which you cited. That is odd & tremendously unfortunate that the researchers failed to mention & make the necessary remarks of distinguishing one from the other, wouldn't you agree? I wonder how they managed to let that happen. Well, as you may gather from my further answer, no, I myself am not aware of any studies that have been conducted wherein it is one Vitamin B12 form implicated in the matter of having a connection to cancer occurring in a user of it rather than the other form being implicated, but, & I am being redundant, I think it is extremely negligent of those who did do research to not have indicated which form was or which forms were implicated. If ever I come across studies that take these things into consideration, I will do my best to revisit here to let you know, though. In the meantime, you probably can check out, say, Dr. Eric Berg's channel, for I know he has before spoken about the two forms I mentioned, & he may very well have mentioned whatever studies he cited to make his remarks. By the way, as I noted in my initial post, yes, indeed, I know cyanocobalamin is indeed unfortunately the form of choice for making most food products & pharmacuetical products wherein vitamins are added, & Vitamin B12 is indicated as being in. Anyway, all the best, & thanks again for your reply. Be blessed.

[@Dr.WenliLiu]

Thank you. @@fiery.mercaba

[@noone7138]

Thank you for the video. I just cut my supplement list thanks to you.

One mora important video!

[@davelawson2564]

typical foolish conclusion . study used very high vit B supplement of just 3 of the vit B. wrongly concluded vit b supplement causes more cancer deaths ?! Typical "educated " Fools