Carbonic Anhydrases

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Пікірлер: 47

@sdparsons 2 жыл бұрын

I love AK lectures' videos. I've been coming back to them to years for learning or refreshing knowledge on various topics. Absolutely class content, I am grateful!

@real01s.50 5 жыл бұрын

finally someone who explains everything !

@rebekahconley895 4 жыл бұрын

fantastic. i love your style of teaching, straight forward info and detailed. thank you!

@kamelkachin7848 8 жыл бұрын

When I watch your videos, I assimilate everything, and it's crafted forever. Thank you so much.

@shafaanmaknojia4135 3 жыл бұрын

excellent video, gives a better understanding by introducing a more detailed theory

@shamimanasrin4546 4 жыл бұрын

it helps me a lot to understand the mechanism, thank u

@bentley1657 4 жыл бұрын

I dont know you..... but I love you, thank you soo much this was so helpful

@ellios5734 2 жыл бұрын

Thank you very much I love the way you explain stuff....saying what's the problem in each part and how the body faces that problem

@anitasrivastava17 3 жыл бұрын

Very informative, nicely explained

@melvinpoole9827 Жыл бұрын

Wonderfully preached, sir. Thank you!

@tommustaki166 5 жыл бұрын

You're the best teacher I've ever had! Thank you very much man God bless you

@lucrijnders2654 5 жыл бұрын

Thank you sir, I'll pass my biochemistry course with your knowledge :)

@nellyhoffman6194 8 жыл бұрын

Man your videos are so awesome !

@vinyasa748 4 жыл бұрын

SLAYYY King! I wish professors and books really broke it down the way you do!

@yashi5172 3 жыл бұрын

Thank you sir Very useful video 👍 And easily understood

@kp-mm7jk 4 жыл бұрын

Awesome lecture... thankyou sir....

@1400740 7 жыл бұрын

Amazingly explained.

@pinnastyers8282 6 жыл бұрын

My instructor needs to play your videos and talk a lot less.

@maharefaat4157 24 күн бұрын

Amazing! ,, thank YOU!

@ivannabby15 4 жыл бұрын

So helpful!! Thank you!!

@graceudoekwere3651 3 жыл бұрын

Please what is the role of specific amino acids residue in the catalysis of carbonic anhydrase

@ermiyasabebe5084 7 жыл бұрын

you are my best teacher ever///////..........................thank you

@MalinLarsson-md9me Жыл бұрын

Thank you!

@uzmayaqub710 8 жыл бұрын

very clear explanation...

@kumarirashmi8293 4 жыл бұрын

Great teaching

@jessn8700 6 жыл бұрын

Great explanation, very well done

@notjennymccarty 2 жыл бұрын

You should think about doing a video on Human Arginase, I'd really appreciate it!

@jonathandavid8932 2 жыл бұрын

Thanks man!!

@noamcabir 4 жыл бұрын

How come oxygen has 3 bond in the start (one with zinc and two with H) and he dont carry a net charge?

@yashitverma8334 3 жыл бұрын

H2O is acting like a ligand instead of forming a Covalent Bond, no need to show any charge

@valerierussell6867 5 жыл бұрын

Thanks!

@manpreetsingh-jg6cb 4 жыл бұрын

is this an example of nucleophilic catalysis by a metal ion?

@snlvl 7 жыл бұрын

Hi! I have a question. Which is the paper of the histidine at the 64th position in this process? My teacher talked about this particular aminoacid but you don't mention it so I don't understand the paper of it in the process. Thank you!!!

@kelseyreinsch7786 6 жыл бұрын

Since you wrote this a month ago, you probably found out the answer... but for anyone else who needs it: His-64 is involved in the proton shuttle, which helps regenerate the active form of the enzyme. A nitrogen in His-64 accepts a proton from the H2O molecule that has bound to the Zinc. The zinc is now bound to an OH- (this is the active form of carbonic anhydrase). The OH- goes on to attack the CO2 in a nucleophilic attack, which is what is explained in this video. The protonated His-64 donates its proton to the buffer (bicarbonate), which concludes the proton shuttle.