Bioisosterism (V. Imp) | physicochemical properties (P-5) | L-7, U-1 | Medicinal Chemistry 1

In this Video we Cover,
1. physicochemical properties in relation to biological action
By @Carewell pharma
bioisosterism
bioisosterism medicinal chemistry
Lecture 7, Unit 1 Medicinal Chemistry 1, B Pharmacy 4th Semester
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Definition :-
In medicinal chemistry, bioisosteres are chemical substituents or groups with similar physical or chemical properties which produce broadly similar biological properties to another chemical compound.
In drug design ,the purpose of exchanging one bioisostere for another is to enhance the desired biological or physical properties of a compound without making significant changes in chemical structure. The main use of this term and its techniques are related to pharmaceutical sciences. Bioisosterism is used to reduce toxicity, change bioavailabilty
Classification of bioisosterism :-
1. Classical
2. Non Classical
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Ethylene diamene tetra acetic acid

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