Carolyn Larabell - Quantitative Imaging of Nuclear Organization

Carolyn Larabell is professor and vice chair of the Department of Anatomy at the University of California, San Francisco. She holds a joint appointment at the Lawrence Berkeley National Laboratory, where she is an advanced light source professor, director of the National Center for X-ray Tomography, and head of the cellular and tissue imaging department. She received her PhD from Arizona State University.
Larabell is a cell biologist with an extensive background in light and electron microscopy and a long history of developing and implementing new imaging technologies. For the past two decades, she has developed biological soft x-ray tomography to image cellular structures in the near-native state. To image molecules with respect to cell structures, her lab developed cryo fluorescence tomography. This technology enables localizing specific molecules using cryo fluorescence tomography and placing them in the context of native-state structures in the same cell seen with cryo soft x-ray tomography.
This talk was given at the 2023 Symposium on Physical Genomics at Northwestern University, sponsored by the Center for Physical Genomics and Engineering and the Robert H. Lurie Comprehensive Cancer Center.