Can You Trust NileRed?

[@fatman9644]

Now we need a third chemistry youtuber to see, whether we can trust Chemiolis

[@skyethebi]

That Chemist sort of did that

[@craigstephenson7676]

@@skyethebinow we need NileRed to see whether we can trust That Chemist

[@skyethebi]

@@craigstephenson7676 I think NileRed should see whether we can trust Sir Humphry Davy. Check to make sure that strontium and potassium really exist.

[@JaredBrewerAerospace]

I vote that we have NurdRage moderate all of this!

[@serenitybysaf]

this aged well

[@Wielorybkek]

in chemistry we don't copy video ideas, we REPRODUCE them

[@Chico_Julio]

In all fields of science is done. And is a CRUCIAL step to theory develelopment, as a validation process.

[@Wielorybkek]

@@Chico_Julio true, it just looks funny from the content creation perspective :p

[@gizmothepiefaceman3062]

@@Wielorybkekonly kinda. While in creation you typically want to do what’s popular, and will get you more sales. In chemistry it’s more about what get you results

[@lynianore7891]

And then we use clickbait titles

[@trustmeimabiochemist3929]

peer review

[@walli6388]

Better Question: Can we trust NileGreen?

[@GAFUKIS]

True

[@informalchipmunk5775]

You can

[@MaC_MoNeY415]

Can we trust Nile Blue?

[@staskielkowski2797]

Phsss its mister now

[@xenajin6827]

I'll do you even better: who's NileGreen

[@vsGoliath96]

Honestly, the point where Nile tried to make cherry flavoring and accidentally created a war crime was one of *the* chemistry moments of all time.

[@devoosdude9809]

He is Canadian so it’s kinda expected

[@itsTyrion]

He what?

[@vsGoliath96]

@@itsTyrion He uh... he miscalculated some things on his recent video where he tried to turn paint thinner into cherry soda flavoring and accidentally created a gas that is banned by the Geneva Convention because it was used as a dispersion weapon during WWI.

[@omgdodogamer4759]

@@itsTyrion he made mustard gas or something

[@vaeger2947]

If you take in to account his heritage it’s even funnier

[@blastron]

off-handedly describing the chromyl chloride cleanup as "I then cleaned it all with water" when NileRed has an entire video documenting his own disastrous cleanup is just a little bit cruel

[@Truth-And-Freedom]

But nile is a creepy little pee drinker

[@Truth-And-Freedom]

​@@nontrashfire2shush with your childish nonsense dear. You don't get to pick what other people call you ......

[@marcellvarga410]

my bad dude, it wont happen again man@@nontrashfire2

[@craigstephenson7676]

@@nontrashfire2 assume deez nuts

[@nenben8759]

Self admittedly Nigel kinda did Make it a bit hard for himself on that cleanup 🤣 Drill vs chromium waste Glass dish looses.

[@mlv3999]

“As a creator, I understand why he left out the yield. As a chemist, fuck you.” 😂

[@129140163]

12:35 😂

[@TheBearInTheChair]

Science and Medicine, one of the few places left in Academia where they throw hands😂

[@TheBearInTheChair]

​@@129140163You are a gentleman and a scholar.

[@Atetrigrams]

That made me laugh because everything else was so subtle or just a bit backhanded😭

[@isaarunarom7830]

came to the comments to check for this before i wrote it myself, not dessapointed to see it as the 5th comment listed.

[@AKATenn]

Nile red wouldn't want you to trust him, he'd want you to look at the source material, and others work too, same as he did.

[@zandaroos553]

I don’t think Nile trusts himself let’s be real here

[@AKATenn]

@@zandaroos553 True, how many scientist got themselves mamed, irradiated, killed tho... seems to be a risk they all take... i think tho, nobody should try this stuff unless they have the right equipment and know how to use it all, and actually know how to do the math... it's chemistry, not alchemy...

[@royk7712]

@@zandaroos553 that's why he always drop and smash a lot of things, he's so frustrated by the reaction so he doesnt even trust himself

[@CoincidenceTheorist]

@@royk7712he’s a showman. He understands the mob

[@gersonrendon2188]

Nile Red is just great. He's huge because he is honest and humble and incredibly committed to improving the quality and variety of his content. You may complain that his videos are not that instructional but then again he's pretty much the only person in the world who can practice chemistry at that level just for fun. I think we should celebrate we live in a period of time in which that is possible.

[@zpbeats3938]

Preach bro 🤙

[@kIngshufle]

De tantos idiomas decidiste hablar factos

[@thehipsterhamster1929]

Factos, jajaja el espanglish xd

[@loll0l114]

Upvote

[@lisaisa]

right because even if he gave us a step by step i’d probably end up killing myself LOL.. i am not a chemist

[@Arcanist_Gaming]

To be fair, he's not doing things to make effective processes, he's just kind of shitposting lmao (and he usually _does_ mention his yields, including those of less than satisfactory runs)

[@Crawfishness]

His videos are largely for shits and giggles, and entertainment. If he was trying to make legitimate tutorial/educational videos, I trust he'd be more professional.

[@izzydo3494]

Especially when half his videos are of him dropping things on the floor

[@Arcanist_Gaming]

@@izzydo3494 He _does_ love to drop things on* the floor lmao. Who doesn't, though?

[@chidori0117]

@@RoastCDuck Do you mean to say there was no established synthesis fpr Benzaldehyde so he had to create one? In which case no there are multiple and he did not have to create one ... if you are talking about another vid why would this be relevant here?

[@samuestos6908]

"I wasn't even trying" To be fair, he deserves to not be appreciated by the chemistry community. To receive disdain from thorough chemists that don't have the attention he has. Nilered is a wonderful magnet to transform normies into amateur chemists. I love him for that reason.

[@wefyb2]

With hindsight, things look messier than they ought to. It is a lot easier to break down a process and make improvements when you have a well edited, 30 minute video to follow to recreate and improve a synthesis. Creators like Nigel are a brilliant resource for providing followable, reproducible processes that are extremely atypical. You can find a million videos of people making "typical" synthesis, but as far as I know, nearly nothing that Nigel has done on his channel is provided elsewhere at any where near the same level of clarity. His videos on Aerogel and ferrofluid are quite literally one-of-a-kind public resources.

[@jsalsman]

It kind of makes you wonder why professional academic chemists don't typically produce video content to go with their synthesis and analysis papers.

[@ExarchGaming]

if nile has a problem, it's laziness. Not doing things properly because he doesn't feel like it. which is totally fine, but it does harm the educational purity of what he's doing. Sometimes I feel like he's lost his spark to create the content, as taking like 8 months to do a single set of reactions is wild. There are chemtubers that make weekly or at least monthly content doing the exact same thing that nile does. Thought Emporium has the same kind of problem, but i think he's a content creator second and a scientist first. at least as far as i'm aware. Nile happens to be the most entertaining, I feel though, E&F is as well, but he's even lazier than nile is, and he could really really do with some upgraded videography.

[@dalfifran7572]

Not doing things properly when the guy using safety equipment and procedure rivaling many uni lab and far outstrip many youtube home chemist is a wild claim. As for taking months for project, i do agree it's slow, not sure about it's "lazy" since we don't know how many multiple project he have, what equipment/resource he need and wait, etc... @@ExarchGaming

[@drewbabe]

@@ExarchGaming fwiw, not necessarily agreeing or disagreeing with you, but he's mentioned in his videos that his content creation pipeline has lots of things happening in parallel, and he often tries to make a video on something, fails, and scraps it. That's pretty common for any content creator who does stuff that requires lots of effort and/or time to make. With that said, most creators who do this have a period where they release stuff infrequently as their pipeline expands, but eventually they kind of "catch up" and are able to put out content regularly, it'll just be content that has been in the works for several months at a minimum. He's been like this for a while, so I can only guess that there are more reasons to it than simply just not having hit a good stride yet. Could be lack of ideas that are working out, lack of motivation or some other kind of burnout, over-focus on his side channels and tiktok/youtube shorts, or any number of other reasons. Only he and the people he's close to really know

[@theexchipmunk]

@@ExarchGaming You are making one really big assumption. That his video are educational in the first place. They really are not, they are generally entertainment. Like how most historical sewing videos are also no intruction, but showing a process thats interesting to some, but mostly with the goal of entertaining and showing what you can do.

[@hukaman88]

I don't trust him to bake cookies thats for sure

[@GigsTaggart]

that was the duumbest waste of money. he's really gone downhill. money made him dumb

[@error-4518]

@@GigsTaggart I bet he earned the money back tenfold, so not really waste of money in that sense lol. But yea money makes creators less creative overall I think.

[@GigsTaggart]

@@error-4518 sure but that's part of the problem. If he can get revenue and patron for doing dumb stuff why would he even bother doing chemistry.

[@maximianocoelho4496]

Its like a new mr. beast, he know what the platform wants, not what chem enthusiast appreciate. I wont deny that he started the chemistry movement in youtube, him and fire&explosions, but I no longer what his stupid videos, I mean, where is the use in cola made from gloves? I really miss when he worked in his parents garage, those videos helped me a lot in college lab (specially the caffeine extraction). Its an equipment for each video and it isnt used anymore. I see him releasing a video in after months, I wonder how the patreons feel about that.

[@oohshiny8713]

Ann Reardon had a look at that, big issues were (1) the chocolate Nile used was 100% cocoa (most commercial dark chocolate is 80% cocoa, 20% sugar); and (2) the flour he used was "hard red spring wheat" - which is quite bitter - but also the flour was packaged in 2013. Using stale bitter flour and no sugar in the chocolate - there was nothing wrong with the recipe itself - the choice of ingredients is what killed it.

[@AquibMohammedAyman]

Well I do not trust him with my life, but otherwise I think he is okay

[@EvanBoyar]

I'd trust more people with my life than I would trust to not finish my fries.

[@AquibMohammedAyman]

@@EvanBoyar but can you trust a person with your life who DOES NOT finish his/her fries?

[@saba-rr8dw]

​@@AquibMohammedAymanyes, because those leftover fries are becoming mine.

[@malcolmhein1858]

I wouldn't trust him with my wife, either.

[@TheTrueForbidden]

"Turning AquibMohammedAyman into Grape Chewy Gummy Candy"

[@seyd5912]

Name a more iconic duo than Chemiolis and the short-path Vacuum destillatilation apparatus . I'll wait.

[@chuckcrunch1]

explosions and fire and plastic cups

[@kaboom4679]

ChemicalForce and the stuff of our collective nightmares .

[@ravencrovax]

​@@kaboom4679i was going to say ChemicalForce and way too many unnecessarily long slow motion shots.

[@jerrysanchez5453]

Extractions and ire and tar

[@mbainrot]

@@jerrysanchez5453 Explosions and Fire AND Extractions and Ire and Orange Chemistry

[@ContemporaryAlchemist]

"...requires advanced knowledge of chemistry acquired through many years of suffering" hit WAY too close to home for me. Ow.

[@prdprdprdprdprdel]

"As a chemist, fuck you" came so far out of the left field.. Great one..

[@129140163]

12:38 Those little things are what makes these videos so entertaining! 😂

[@thecountrychemist2561]

That got me laughing. Same though. I need to know

[@skyethebi]

That Chemist: “Can we trust Chemiolis?” Chemiolis: “Can we trust NileRed?” NileRed: “Can we trust Sir Humphry Davy?”

[@BackYardScience2000]

Now it's turning into "can we actually trust That Chemist?".

[@TK-en2hq]

"trust is mostly irrelevant to science" Spoken like a man who has never blindly replicated a lab experiment from the 70's. Trust is like, 90% of not dying during experimental replication.

[@draggy76]

by how much shit he has to look up and how little he most likely knows about science, i'd say you hit the nail on the head there.

[@IAOIceland1984]

​@@draggy76​ do you think science is just experimenting wildly using your intuition? Just look at a scientific paper mate, we back up each and every sentence with a paper justifying the information in the sentence. You should not trust your memory in science, look shit up and confirm what process is best for each step of a reaction as well as possible reaction paths.

[@mozarteanchaos]

@@draggy76 sorry, do you think scientists actually just hold all information relevant to their field in their heads at all times or something? they're people, not computers.

[@FullThrottleRacing535]

@@draggy76 Stupid reply to be honest.

[@kev3d]

"Don't put that potassium in your mouth! it's extremely reactive!" "I don't trust you."

[@FriedEgg101]

To be fair to NileRed, he kind of makes a thing about not being that scrupulous with his method; like a soft-core edgyness. And I guess that's part of the appeal? But he appears to freely admit to cock ups, and from someone with just chemistry a-level (me) he seems to explain the chemistry well too. I see no reason not to trust him, at the level that I need to trust him. This video was also interesting though. Can't complain at more chemistry content.

[@ashrowan2143]

Yeah I definitely don't have a high enough understanding of Chem to reproduce any of his tests myself but from the stuff I do know his science is solid he screws around and uses tools he doesn't need to for the fun of things so I trust that he's creating what he says he is to the level I need to which is fun science man who's making things for the hell of it

[@nickpekor4450]

First Explosions&Fire and now NileRed. Who's the next target for Chemiolis to start chemistry beef with?

[@Yiiino]

Chemdelic? 🤔

[@quint3ssent1a]

Prussian Blue. I bet Chemiolis will have a cardiac arrest once he catches a whiff of what this mad lad is cooking.

[@T3sl4]

Heck with that, where's Greeniolis at??

[@foxyfoxington2651]

Chemiolis takes down himself in a long, weird, recursive beef that loops until it eventually collapses in on itself and forms a black hole from which no views or likes or comments can escape. Make it happen!

[@BillAnt]

I trust Chemiolis more than the other guys, this dude is good... really good.

[@gempio2634]

To be fair, Nile always says that he isn't doing his experiments with yield in mind. Just wants to take the quickest route to getting the substance so yeah... Not really mad that his yields are shit. The man admits it himself

[@isocle]

The clickbait we all deserve

[@vincenzo5816]

>Want to fix errors of others >Handles dangerous chems with exposed arms

[@abnorc8798]

Safety violations increase engagement via the comment section, which is far more important.

[@aiexzs]

@@abnorc8798 i'm so so so sure you're thinking too far into it

[@nathanlamaire]

​@@abnorc8798💀

[@abhaybhatt4286]

It balances out with NileRed pouring the most dangerous shit without a funnel

[@muffinconsumer4431]

@@abhaybhatt4286 Pour like you mean it

[@cypherusuh]

He's chemist with high-grade equipment and safety measurement. But we don't watch his channel for just science, but because he's entertaining us with actual science. It's called Edutainment, not online class.

[@Yahya98]

Exactly. Well said. We don't watch his channel for science, but to fall asleep 😂

[@platty9237]

I think that’s implied. This seems more like a challenge to see if the experiment is somewhat reproducible.

[@Stahlwollvieh]

00:13 "...even if we do trust him - trust is mostly irrelevant to science. Instead, we should use the most important pillar of science: reproduction." *proceeds to open pornhub*

[@aqua-bery]

I thought this was gonna be a compliment for a hard hitting code

[@michael9679]

What the f-

[@hotketchup100]

Today, I had my first analytic chemistry lab. It was only orientation, and going over sylabus, but I still managed to have a look around the (really old, like waaaaay too old) lab, and I saw a 2L bottle full of chromyl chloride (full), and as I leaned in, to read the label (wanted to know the year, and it was 1987), the teacher just came over to me, and just told me to keep away from that cabinet, as it was actually filled with a lot of other solutions, including some dichromates, and other. Let's just say, I'll be extra careful, not to knock anything over, as I will be working pretty close to it. The best part is, that the cabinet isn't even locked. And neither are the labs (why? I have no idea).

[@urazon9465]

In my city there is a research institute which is the merge of several smaller labs. When they moved in their new, big and fancy lab, they lost some uranium rocks like ten years ago, nobody knows where those are to this day.

[@xenajin6827]

Same in my college too😂. They haven't locked the cabinets and have some starting products to make explosives like trinitrotoluene💀

[@moonik665]

The reason it's not locked is because it can defend itself.

[@hendraibaraki]

Maybe for safety reason... If for any reason.. any of that chemical storage exploded.. fall or anything.. it will be easy to evacuate out of the lab.. instead locked in

[@dangoldbach6570]

I was installing a fume hood in a lab and the ancient cabinet next to me had to move over. I opened the door and find a 1kg. Bottle of potassium cyanide smiling at me. Gently closed door, Backed out of room.

[@carterpochynok4874]

Its really cool that you chem KZbinrs seem to be teaming up to test each other's methods and demonstrate peer-review to your audience in the form of entertainment. Keep it up!

[@barfbot]

just seeing two chemist (amateur or otherwise) doing the same procedures can be very enlightening when it comes to lab techniques

[@outcastatsabre]

But why wouldn't you taste test something prepared with carbon tet and hexavalent chromium??😮

[@EddieTheH]

Also known as "Detroit mineral water" 😁

[@foxyfoxington2651]

That's what always got me about the original video: Making soda using the most carcinogenic and toxic route humanly possible and then drinking it for views.

[@EddieTheH]

@@foxyfoxington2651 Confidence in the chemistry.

[@justsomeguy5628]

Exactly. Any imperfections just add unique flavor that you will almost certainly remember for the rest of your life.

[@TS-jm7jm]

​@@justsomeguy5628lol, for however long that ends up being

[@NickGarcia1519]

Peer review and reproduction are two very different and very important processes in science. Peer review is when experts read and critique articles before they are published. Reproduction is when other labs try to reproduce the same results, like with lk99

[@Shorty50]

Nile red has a very advanced home lab and I think sometimes he over does very simple steps in procedures which more than likely impacts his yields :)

[@gi7892]

I think this exact thing whenever he touches anything that resembles a tool.

[@ExarchGaming]

he's lazy, that's all. that's why his yields get fubared. it's part of his charm, same with Explosions and Fire.

[@JaredBrewerAerospace]

Have you seen his new lab? He offhandedly has a tube furnace and an NMR that he's used once. It's far from a home lab.

[@JaredBrewerAerospace]

@@ExarchGaming I feel that Nile tries hard to be a real chemist. E&F is a super smart dude and does it for fun, which is where I find the entertainment value.

[@thejohnkaufman]

​@@JaredBrewerAerospaceE&F is also technically a physicist, which makes his chemistry shitposting in a shed even funnier

[@MegaBrokenstar]

The quality of science on KZbin is increasing constantly and I’m loving it. Peer review, reproduction, formal scientific disputes, it’s amazing. A whole new venue for scientific research, funded by the curiosity of viewers rather than the potential for industrial profit.

[@birblover6423]

Im loving it honestly, never did i think i would see someone peer review nile red and its been 2 times now! Both incredibly done and educational as well :)

[@Dr_Mario2007]

I just generally like watching NileRed, as well as the other chemists including Chemiolis as well, as I like to see how they put chemicals together to make something, including my favorite, fluorescent chemistry.

[@Vile_Entity_3545]

He makes very entertaining videos.

[@mookinbabysealfurmittens]

You might like ChemicalForce (lots of glowing, sparks, etc. & nice shots) and StyroPyro (more into lasers & engineering but is a chemist proper, and lots of glow!)

[@Vile_Entity_3545]

@@mookinbabysealfurmittens He makes the best. That video nearly a year or so ago that looked like a mini nuke was the bees knees.

[@mookinbabysealfurmittens]

@@Vile_Entity_3545 I like Styropyro's little squirrel pal. And his newest full video (not short) is pretty impressive. There's more than one mushroom cloud!

[@Isissa125]

im a tar chemistry man myself

[@skotdude]

You forgot the part where he actually makes his videos entertaining.

[@chinjunsi7752]

You are asking can we trust nilered but I'm now asking can we trust YOU?!?

[@kaiying74]

I'm a Computer Scientist with bad High School chemistry, I have no idea what either you or Nile are talking about. I still watch fascinated at you guys doing what looks like magic to me.

[@Peter_Lustik]

Man, you should really be a bit more careful when distilling ether. The Setup at 11:03 screams for a fire. I've heard of many cases where ether fumes ignited on a hot plate, its really not fun. Make sure to use a roundbottom next time. D:

[@MichaelLapore-lk9jz]

D-i-stilling! Not destilling!

[@Peter_Lustik]

@@MichaelLapore-lk9jz fixed!

[@phobos1963]

Finally some drama in the youtube chemistry community (don't touch prussian blue you will end up finding a pipe bomb in your next delivery)

[@logancontracier7125]

I think that’s what’s crazy to me about chemistry is that there is so many different ways to try to get the same product but with varying results

[@magiclegume]

Sure NileRed had a lot of screwups and this video does seem like he’s better and cleaner but let’s remember that this is a second attempt. As all things in experimentation goes, the 1st attempt usually gets most of the erroneous paths. Ergo, the 2nd has a much more straightforward way of getting it right, and in a cleaner way too.

[@Salamandra40k]

A big explanation for how and why Nile seems to have his videos always be chaotic is just...how he is. Go watch him try to make anything that isnt necessarily chemistry- the "making my own chocolate" and "making a bismuth knife" videos are great examples of how you can see he reacts to things normally...as in, he really has no idea what hes doing, and just makes guesses, which usually turn out sliiiightly wrong, but mostly right. Not to say he isnt smart, at all, I'm simply saying he has no patience and can be disorganized

[@SubmarineCommander]

I feel like this is just a wizard insulting another wizard.

[@fire-ballmc9741]

This is genius! Make videos in a very similar way to nilered a channel who uploads like 3 times a year and then make a video with a clickbait title about him that would make nilered viewers curious so you get allot of his audience and because of the similar style allot will probably stay! edit: This is not meant to sound negative.

[@victoralvarez2956]

"As a creator, I understand that he left out the yield... As a chemist, FK YOU!" Damn! That was personal 💀💀

[@dahat1992]

So, "amateur chemist in their 20s is inefficient and make mistakes" is somehow news now?

[@TheSectric]

I like how he acts like Nile doesn't also constantly mention his method was inefficient. Like I swear one of his most said phrases in his videos is "there is probably a way better way to do this but here's what I did"

[@theprogrammer32]

"As a creator, I understand... As a chemist, fuck you." literally just sums up a lot of his content tbh

[@129140163]

12:35

[@davidestabrook5367]

The way NileRed destroys glassware, it's crass. Glassware costs money, and he's intentionally breaking it to get KZbin views, it's not a good look. It makes him come across as an entertainer, who's playing at chemistry, rather than someone who enjoys chemistry and takes it seriously.

[@General12th]

@@davidestabrook5367 If it's his own money, who cares?

[@davidestabrook5367]

@@General12th Obviously I care. There is a market for "Will it blend?" videos, and videos of people, buying brand new iPhones, then smashing them up, in front of the line of people queuing to get one. There's also a market for watching sports like boxing and American football, which cause physical injury and traumatic brain injuries. But I prefer chemistry videos, which show actual chemistry, and the equipment being treated with respect. As that's useful information, rather than content slop. NileRed intentionally dropping things, and smashing glassware is content slop, not useful information, and I do care about that.

[@IntelCorei-KProcessor-go2to]

@@davidestabrook5367 He is very obviously an entertainer, and has stated that he loves videography more so than he does chemistry. His audience are majorly non-chemist people and they like his unhinged stunts. If you follow Nile for serious chemistry you will have to just accept the fact that you're a minority.

[@LouiesLog]

He's one of the few people I would instantly trust just from personality. I know you shouldn't but he is not purposely misleading, I think he has a more enjoyable way of doing things rather that doing everything for perfection. I guess it's a good way to get views to critique a bigger KZbinr.

[@thaddeusk]

I trust him enough that I don't need to watch this video.

[@ucantSQ]

13:52 Thank you! First time I heard him casually say, "I'll run it through my NMR," I nearly spewed. How does a KZbin chemist afford an NMR? I'm glad someone else uses the chemoreceptors they were born with!

[@csmac3144a]

NileRed will probably be responsible for thousands of kids deciding to go into chemistry. Are his videos scientifically flawless? Probably not since he's doing them to entertain and educate people, not do actual research. He's popular because he's likable, unlike most of the cynical losers taking shots at him in the comments here.

[@ipiqqyfpv]

This would be really cool as a video series

[@theIargedude]

chemiolis once again proving that he's an attack chemist

[@Areavate]

10:12 From my experience is advice that acqueous phase(bottom layer) is separated using the faucet instead the organic phase(top layer) using the upper part of the separatory funnel. Since most of the time the product of interest it's in the organic phase using this method you prevent contamination with what's in the acqeous phase

[@GoodBoyAnatoly]

Two of the best Chemistry KZbinrs, I want them to colab and make met-.

[@Crawfishness]

Methyl anthranilate!

[@daltonsoutherland8836]

The way he just casually talks about using chromyl chloride and carbon tetrachloride otherwise known as the cancerous superduo 😂

[@pzyko21]

I am really curious how this channel will do in a year or two, i really like it, short, info packed, and from the looks pro safety chemistry videos. i dont understand half the things but your words make me partly understand it funny liquid man

[@giupinkfairy]

I wish I had a quarter of his equipment. Have you seen his Spectrophotometer?????? Not even my university has half of his equipment

[@mopippenger7373]

First Extractions and Ire, now NileRed... who's gonna get their villain origin story next?

[@ananteshesha5788]

I know you are dutch Chemiolis you cant hide your dutch accent from a fellow dutchman

[@defenestrated23]

"In this video, I dunk on Nigel's chemical techniques and get better yields. "

[@Tomnickles]

Since I don't watch KZbin to reproduce the video's I see, sure we can trust him.

[@m3m3sis]

I never took his videos as purely educational but playful and inspirational. I think people should take everything with a grain of salt if its not from an official governmental body and even then I'd hold a healthy amount of skepticism.

[@shimmya]

That’s fair to assume but it would be great if he added a disclaimer about that somewhere

[@mylesswanson]

I'm honestly having a hard time telling if Chemiolis likes or dislikes NileRed content. I haven't watched too much of Chemiolis stuff (yet), so I don't know if he is being legitimately critical ("as a chemist, **** you"), or if his humor comes in the form of a flat faced sarcasm. Someone enlighten me.

[@lebo1999]

i love how youtube science has gone so far that (even if as a meme) we have youtubers peer reviewing youtubers 20/10 meta content

[@leelammajohnvarghese8143]

This is the way benzaldehyde is made in higher secondary school chemistry labs. Cro2cl2 vapours are passed through toluene and the mixture is poured into a freezing mixture (usually just ice and water). The presence of c6h5cho is inferred by smelling it. The bitter almond smell is positive for thr aldehyde. I saw the nile red video and i think he didnt take into consideration, concentration of reactants, temperature, the side reactions in the decomp. Of intermediate products and the actual yield of the desired product. Its fun to watch for a novice or someone interested in chem. But for someone with a higher degree in chemistry its a farce. Just reading about the reaction requirements of the etard reaction would be enough to successfully film the reaction and obtain a yield of less than 20pc) but i guess the idea behind the video was to fail a couple of times and then end the video in ambiguity.

[@benpurcell4935]

Nilered has a Bachelor’s degree and was in a graduate program for chemistry. The entire reason he makes videos is to show that chemistry isn’t all like what you experience in school. He even got a minor in pharmacology.

[@giacom312]

That chromyl chloride mechanism hurt my organic chemist's eyes and soul

[@humanbean3]

i should start a chemistry channel and just mix random liquids together and just pretend to produce some chocolate or maybe gummy bears or something

[@twosquids]

You have a promising tiktok career

[@dzhangarbadmaev1057]

Great idea, reproducibility is important

[@TonyDeBlark]

11:03 If you gonna do this, you gonna have a very bad time. Vapors are very flammable and can easily ignite from the heat

[@fmdj]

This is probably a tough question to answer but I keep asking it to myself (not a chemist): to what extent do we understand what goes on in a chemical reaction? like, say I wanna synthesise a given compound: is there in general a finite set of rules I can look up and use to eventually deduce a synthesis procedure, or will there be a lot of reaction-specific knowledge that requires a lot of trial and error?

[@JossCard42]

As I (another non-chemist) understand it, we have a pretty good idea of what's going on inside a given chemical reaction, provided we know all the materials involved. Most of early chemistry revolved around A lot of chemistry projects are 80% figuring out what is going to happen on paper long before you start adding chemicals in beakers. If you're interested, the Crash Course channel on KZbin has a series on chemistry that has helped me get a better understanding of what's actually happening inside those flasks and also briefly covers the big discoveries that led to our current understanding of chemistry.

[@MDNQ-ud1ty]

ZERO. you have zero understanding of what is going on. What you learn is not what, how, or why BUT *when*. 99% of so called scientists completely fail at having a clue what they are doing and it makes them dangerous. Like a kid that has a gun and thinks he's a gun expert or a government that has nukes and thinks they are gods gift to humanity. All science is is models of reality(*MODELS*). Science works by making those models approximate reality until they no longer work to achieve new results(which is why science is stagnating now). Statistics/repeatability is what makes things work and provides the answers for the *when*. E.g., *When* I do X and Y and then Z I get Q. All science is is statistics applied to logic for approximate the cause and effects of temporal coherency. It works quite well because the universe is relatively stable currently.

[@EddieTheH]

As with most science, it was all trial and error in the early days, when enough is discovered by trial and error for patterns to emerge, the picture gains more and more resolution, which gives us more data to make more accurate predictions. Now we have some pretty decent software to model reactions based on previously gathered data, which is more or less accurate. We can pick and choose chemical building blocks with various functional groups and how they behave (how to assemble and disassemble them), these narrow down the possible reactions to the point where organic synthesis is almost akin to Lego, only putting the blocks together isn't quite as simple. When it gets to the actual practical application, reactions are mostly predictable now, so we return to the trial and error to fine tune the synthesis. Tweaking variables one at a time until we get consistent, repeatable results. Chemistry involves a *lot* of repetition. Chemistry involves a *lot* of repetition. Chemistry involves a *lot* of repetition. 😁

[@fmdj]

very helpful thank you both!

[@MDNQ-ud1ty]

@@fmdj both doesn't include me since there are 3 replies in the last hour. I'm likely shadow banned, can you verify?

[@JustAPakistaniGamer]

man what a title... as a marketer and an SEO specialist... gotta give you credits for good homework and research... !!!! know that your genius is appreciated... content is also quality !! so double thumbs up on that.... Don't stop keep it up... 1 million subs await... :) Good luck

[@meatmobile]

'no drama', clearly made to start drama

[@tanvach]

13:45 I don't know why, but seeing that tiny stir bar spin make me chuckle

[@TheBackyardChemist]

I usually dont bitch about atom efficiency, but this Étard reaction is something truly horrendous. You want to oxidize something, but your oxidant remains still mostly oxidized in the Étard complex, so you have to add a bunch of reductant to workup your oxidation reaction... What an awfully wasteful reaction.

[@NinoNiemanThe1st]

The title of this video is clickbait, just someone trying to use Nile Red's search results to get KZbin views - Chemiolis's chemistry techniques are better though the title makes it very 'climb on someones else's bandwagon' for a few extra views/cents. I like both channels.

[@Digital.Dictator]

Someone quickly inform NileRed let's get this youtube drama started.

[@silksongoutyet]

can't wait for the diss tracks

[@4shotpastas]

"As a creator, I understand why he left out the yield, as a chemist, fuck you." Poor Nigel XD

[@Lancasterlaw1175]

Huh, the sulphuric acid out of the freezer looks disturbingly refreshing.

[@bubbyguppy]

People out here in the comments literally getting mad over peer reviewing. What the heck are you people on

[@caldilworth1344]

I love this idea and hope you keep testing our NileRed's syntheses!

[@f0rtuzer0]

Funny because I literally just watched a video by `That Chemist`titled `Can we trust Chemiolis?`... lol. Who guards the guards, and all that.

[@Anumera]

Was looking for this because the same happened to me. Can't wait for the 4th in the series, since is turtles all the way down.

[@DeVoidLij]

Nilered should seriously publish a paper detailing every step he takes for his syntheses

[@maxxuel9181]

But what makes you think that we can trust you? 🤨

[@ArysenNoName]

You just opend a paradox cause… how can I trust you?

[@Manarinni]

One thing I'd like to add is that Nile is very honest and straight forward in saying that he is learning, and he is very open when things don't go his way, and you got to give him that

[@ommhatre3645]

The oxygen does not take a proton from the toluene before the double bond of the ring attacks the chromium its vice versa in my opinion cuz the oxygen isn't basic enough and the hydrogen isn't acidic enough to drive the reaction. So the double bond of the ring attacks the chromium first(which breaks a chromium oxygen bond simultaneously and an O- is formed) leading to formation of a carbocation which then pulls electrons from the carbon hydrogen bond making the hydrogen very acidic. It is then deprotonated by the O- forming the following intermediate product

[@madoba8717]

As a chemical engineer, I leave it up to the chemists

[@KlausRosenberg-et2xv]

You can't trust someone who made an entire video cooking the "most pure cookie" in the world when in fact he confused the ingredients being actually and extensively tested in laboratories for the calibration of equipments, and not aiming the products to be pure.

[@zenithparsec]

This is a chemistry diss-track.

[@thefinalkayakboss]

"As a creator, i understand that he left out yield, As a chemist.... fuck you" Im no chemist but that was some funny relatable shit.

[@ClearlyJoking]

You can definitely trust him to make something stinky

[@lautaromorales2903]

8:28 sulphite can protonate and give HSO3- without those intermediate steps. 9:05 the Cr6+ that you have there it's highly electrophilic, probably the water attacks the chromium and leaves behind the oxigen bonded to the carbon that later on attacks the carbon and expells the remaining HCrO2Cl2--. The mechanism should be symilar as metal halides hydrolysis or sulphonate ester hydrolysis.

[@Zettymaster]

"wet it with some carbon tet" bro is just casually using the ozone destroyer 9000 for wetting filter paper

[@abhaybhatt4286]

I dont get why NileRed didnt just go with the halogenation --> substitution --> oxidation pathway, looks way safer and less random in terms of regiochemistry assuming he uses some protecting groups. I think he just wanted to use kewl blood juice lol

[@Leoo___]

Next video: NileRed: can we trust Chemiolis?

[@cooldude7301]

Nobody cares what Nile red thinks. He sucks

[@alexpotts6520]

Next NileRed video: turning Chemiolis into strawberry milkshake

[@Hellooo134]

I just realized I’m watching a chemistry video… to procrastinate doing my chemistry homework

[@awli8861]

but can we trust you?

[@Jofoyo]

I'm not sure we can trust this guy, might need a peer review.

[@yeoldebaccyfarm3081]

sensory analysis. my favorite analytical method.

[@topsunnn]

I love NileRed. Can't wait for his uploads

[@sinecurve9999]

12:43 Geeez dude! You're taking this waaay too personal.