Рет қаралды 145,101
Subscribe to Curiosity Stream and start exploring the world around you! bit.ly/CuriosityStreamChemiol...
In this video I am making and self-testing the molecule Capsazepine (albeit crude), a molecule that blocks access to the receptor activated by the spicy-molecule capsaicin, thus removing its ability to cause you the spicy feeling. There is no known literature on its use on humans, it is used to study the TRPV1 ion-channel (spicy/heat receptor) but only in biology or biochemistry.
For the azepine: onlinelibrary.wiley.com/doi/1...
For the isothiocyanate I used a general procedure from: scihub.se/doi.org/10....
For the final coupling: sci-hub.se/doi.org/10...
Support my channel with patreon:
/ chemiolis
Check out @LabCoatz_Science who notified me of this molecule.
This video is sponsored by Curiosity Stream.